Back to Peptides
Peptides

DihexaEvidence & Dosage

Angiotensin derivative, cognitive/neuroplasticity signals in animal models.

Evidence at a glance

Total studies
20
With abstract
19
Meta / Systematic / RCT
0
Highly cited
1
Publication years
2011–2025

Dihexa in the context of Peptides

This topic is part of our "Peptides" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

Go to Peptides

Top studies on Dihexa

Ranked by influential-citation count and publication year.

  1. Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors.

    Nature2011147 influential citations

    The generation of functional hepatocytes independent of donor liver organs is of great therapeutic interest with regard to regenerative medicine and possible cures for liver disease. Induced hepatic differentiation has been achieved…

  2. The Brain Hepatocyte Growth Factor/c-Met Receptor System: A New Target for the Treatment of Alzheimer's Disease

    Journal of Alzheimer's Disease2015

    Alzheimer's disease (AD) is a progressive neurodegenerative disease increasing in frequency as life expectancy of the world's population increases. There are an estimated 5 million diagnosed AD patients in the U.S. and 16 million worldwide…

  3. Expansion and differentiation of human hepatocyte-derived liver progenitor-like cells and their use for the study of hepatotropic pathogens.

    Cell research2019n=7,459

    The study of pathophysiological mechanisms in human liver disease has been constrained by the inability to expand primary hepatocytes in vitro while maintaining proliferative capacity and metabolic function. We and others have previously…

  4. Scalable production of tissue-like vascularized liver organoids from human PSCs

    Experimental & Molecular Medicine2023

    The lack of physiological parity between 2D cell culture and in vivo culture has led to the development of more organotypic models, such as organoids. Organoid models have been developed for a number of tissues, including the liver.…

  5. Evaluation of Metabolically Stabilized Angiotensin IV Analogs as Procognitive/Antidementia Agents

    Journal of Pharmacology and Experimental Therapeutics2012

    Angiotensin IV (AngIV: VYIHPF)-related peptides have long been recognized as procognitive agents with potential as antidementia therapeutics. Their development as useful therapeutics, however, has been limited by physiochemical properties…

  6. Pluripotent stem cells to hepatocytes, the journey so far

    Biomedical Reports2017

    Over the past several years, there has been substantial progress in the field of regenerative medicine, which has enabled new possibilities for research and clinical application. For example, there are ongoing efforts directed at…

  7. Small‐Molecule‐Directed Hepatocyte‐Like Cell Differentiation of Human Pluripotent Stem Cells

    Current Protocols in Stem Cell Biology2016

    Hepatocyte‐like cells (HLCs) generated in vitro from human pluripotent stem cells (hPSCs) provide an invaluable resource for basic research, regenerative medicine, drug screening, toxicology, and modeling of liver disease and development.…

  8. Development of a rapid screen for the endodermal differentiation potential of human pluripotent stem cell lines

    Scientific Reports2016

    A challenge facing the human pluripotent stem cell (hPSC) field is the variability observed in differentiation potential of hPSCs. Variability can lead to time consuming and costly optimisation to yield the cell type of interest. This is…

  9. Hepatocyte-like cells derived from human induced pluripotent stem cells using small molecules: implications of a transcriptomic study

    Stem Cell Research & Therapy2020

    Background Hepatocyte-like cells (HLCs) derived from human induced pluripotent stem cells (iPSCs) hold great promise in toxicological applications as well as in regenerative medicine. Previous efforts on hepatocyte differentiation have…

  10. Robust expansion and functional maturation of human hepatoblasts by chemical strategy

    Stem Cell Research & Therapy2021

    Background Chemically strategies to generate hepatic cells from human pluripotent stem cells (hPSCs) for the potential clinical application have been improved. However, producing high quality and large quantities of hepatic cells remain…

More topics in Peptides

Peptides Overview

Peptides, BPC-157, TB-500, safety and the state of the evidence.

Administration Routes

Subcutaneous, intramuscular, nasal, oral, topical — bioavailability and safety.

Autoimmunity Risk

Immune modulation can both promote tolerance and tip into dysregulation.

BPC-157

Peptide for tissue regeneration, healing, and athletic recovery.

Cerebrolysin

A pig-brain peptide mix, stroke studies, not approved in Germany.

CJC-1295

GHRH analog, half‑life variants and pulse patterns.

GHK-Cu

Copper peptide for skin health, anti-aging, and wound healing.

GHRP-2

GH releaser, older generation, appetite stimulation as a side effect.

GHRP-6

GH releaser with a strong appetite component.

GLP-1 Rebound

Weight regain after stopping without lifestyle anchors.

GLP-1 Side Effects

Nausea, gastric emptying, muscle loss, pancreatitis risk.

Hexarelin

GH releaser, fast tolerance build-up, cardiac signals.

IGF-1 LR3

Modified IGF-1 with a long half-life — hypertrophy, the cancer-risk debate.

Immune Modulation

Automatisch via Trend Scout entdeckt. Supplements targeting inflammation and immune resilience remain a central research area.. PubMed: 11956 Ergebnisse.

Injection Safety

Sterile technique, bacteriostatic water, skin disinfection — a medical topic.

Ipamorelin

Selective GH releaser, cortisol‑sparing, and stack combinations.

KPV

An alpha-MSH fragment — anti-inflammatory, gut, skin, early research.

Liraglutide

First-generation GLP-1 for diabetes/obesity — daily, smaller effect size.

LL-37

Antimicrobial peptide, wound healing, immune modulation, early research.

MK-677

Ghrelin mimetic, not strictly a peptide — sleep, appetite, glucose risk.

Related topics from other worlds

Hormones

IGF-1

Insulin-like growth factor — growth, anabolism, the longevity trade-off.

Hormones

PCOS

Polycystic ovary syndrome — insulin resistance, androgens, lifestyle.

Hormones

Receptor Sensitivity

Up-/downregulation, tolerance, hormone resistance as a phenomenon.

Hormones

Thyroid Function

Thyroid function for metabolism, energy, and mental clarity.

Cognition

Bacopa Monnieri

Memory, Bacosides, Long-term Effect and Tolerance

Cognition

Deep Work

Focused, distraction-free work as a trainable skill.