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GHRP-2Evidence & Dosage

GH releaser, older generation, appetite stimulation as a side effect.

Evidence at a glance

Total studies
1,000
With abstract
50
Meta / Systematic / RCT
0
Highly cited
50
Publication years
1968–2026

GHRP-2 in the context of Peptides

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Top studies on GHRP-2

Ranked by influential-citation count and publication year.

  1. Neuroendocrine control of growth hormone secretion.

    Physiological reviews1999138 influential citations

    The secretion of growth hormone (GH) is regulated through a complex neuroendocrine control system, especially by the functional interplay of two hypothalamic hypophysiotropic hormones, GH-releasing hormone (GHRH) and somatostatin (SS),…

  2. Structure-function studies on the new growth hormone-releasing peptide, ghrelin: minimal sequence of ghrelin necessary for activation of growth hormone secretagogue receptor 1a.

    Journal of medicinal chemistry2000114 influential citations

    The recently discovered growth hormone secretagogue, ghrelin, is a potent agonist at the human growth hormone secretagogue receptor 1a (hGHSR1a). To elucidate structural features of this peptide necessary for efficient binding to and…

  3. The effects of 10 years of recombinant human growth hormone (GH) in adult GH-deficient patients.

    The Journal of clinical endocrinology and metabolism1999n=1079 influential citations

    The long term effects of GH replacement in adult GH-deficient (GHD) patients have not yet been clarified. We studied 21 GHD adults who originally took part in a randomized, double blind, placebo-controlled trial of GH treatment in 1987.…

  4. Serum levels of insulin-like growth factor I in 152 patients with growth hormone deficiency, aged 19-82 years, in relation to those in healthy subjects.

    The Journal of clinical endocrinology and metabolism1999n=24757 influential citations

    Serum insulin-like growth factor I (IGF-I) levels within normal range for age have been reported to be common in adults with GH deficiency (GHD). Therefore, serum IGF-I levels were determined in 152 consecutive patients (71 women and 81…

  5. A 2024 Update on Growth Hormone Deficiency Syndrome in Adults: From Guidelines to Real Life.

    Journal of clinical medicine202450 influential citations

    <b>Background:</b> Adult growth hormone deficiency (GHD) has been recognized since the late 1980s. The clinical manifestations of adult GHD are often nonspecific, and diagnosis relies on GH stimulation tests, which are intricate, costly,…

  6. Pituitary and testicular function in growth hormone receptor gene knockout mice.

    Endocrinology199936 influential citations

    The role of GH in the control of pituitary and testicular function is poorly understood. GH receptor gene knockout (GHR-KO) mice were recently produced. As these mice are good experimental animals to assess the influence of the effects of…

  7. Jointly amplified basal and pulsatile growth hormone (GH) secretion and increased process irregularity in women with anorexia nervosa: indirect evidence for disruption of feedback regulation within the GH-insulin-like growth factor I axis.

    The Journal of clinical endocrinology and metabolism199934 influential citations

    Anorexia nervosa (AN) is associated with multiple endocrine alterations. In the majority of AN patients, basal and GHRH-stimulated serum GH levels are increased. The metabolic effects of GH are known to be related to its pulsatile…

  8. Growth hormone-releasing peptide (GHRP)

    Cellular and Molecular Life Sciences (CMLS)199832 influential citations

    Growth hormone-releasing peptides and non-peptides (GHRPs. GHRP-GHS) are a new chemical class of GH secretagogues with a chemistry that ranges from small synthetic peptides to peptidomimetics. They release GH in animals and humans by a…

  9. Influence of sex, age and adrenergic pathways on the growth hormone response to GHRP‐6

    Clinical Endocrinology1993n=1231 influential citations

    <h4>Objective</h4>His-dTrp-Ala-Trp-dPhe-Lys-NH2 (GHRP-6) is a synthetic compound that releases GH in a dose-related and specific manner in several species including man. To further characterize the effects of GHRP-6 on GH secretion in…

  10. Identification of a Pituitary Growth Hormone-Releasing Peptide (GHRP) Receptor Subtype by Photoaffinity Labeling

    Endocrinology199830 influential citations

    Hexarelin, an analogue of GHRP-6, in which D-Tryptophan has been replaced by its 2-methyl derivative, is known to release growth hormone (GH) in vivo and in vitro by direct action on receptors present in anterior pituitary cells.…

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