Acute vs Chronic InflammationEvidence & Dosage

Top studies on Acute vs Chronic Inflammation

Ranked by influential-citation count and publication year.

1. 01

   Accelerated vs Step-Up Endoscopic Treatment for Pancreatic Walled-Off Necrosis: A Randomized Controlled Trial (ACCELERATE)

   Clinical Gastroenterology and Hepatology·202629 influential citations

   <h4>Background & aims</h4>Endoscopic step-up treatment with ultrasound-guided drainage and necrosectomy has become the gold standard treatment of pancreatic walled-off necrosis (WON); however, the length of stay (LOS) in hospital of…

2. 02

   Risk-Adjusted Outcomes of Reoperative vs Primary Coronary Artery Bypass Grafting

   The Annals of Thoracic Surgery·20261 influential citations

   <h4>Background</h4>Coronary artery bypass grafting (CABG) is a mainstay of therapy for advanced coronary artery disease. The proportion of reoperative CABG has declined to ∼3% to 7% of all CABG procedures; however, redo operations remain…

3. 03

   Long-Term Outcomes of Repeated Transcatheter Aortic Valve Replacement vs Transcatheter Aortic Valve Replacement Explantation: A Nationwide Analysis

   The Annals of Thoracic Surgery·2026·n=1,1721 influential citations

   <h4>Background</h4>Comparative durability of subsequent procedures after transcatheter aortic valve replacement (TAVR) remains unclear. This study aimed to assess long-term outcomes of repeated TAVR vs TAVR explantation for bioprosthetic…

4. 04

   Opioid-based vs. opioid-free analgesia in hip arthroplasty: A systematic review and meta-analysis

   Anaesthesia Critical Care &amp; Pain Medicine·2026

   <h4>Background</h4>Hip arthroplasty is a standard surgical procedure to decrease joint pain. Opioid-based regimens have historically been used to treat postoperative pain; however, opioid-free regimens are increasingly employed due to the…

5. 05

   Direct oral anticoagulation interruption vs continuation in patients undergoing elective invasive coronary angiography or percutaneous coronary intervention: Design and rationale of the South Limburg Myocardial Infarction Study Group Trial 2 (SLIM-2)

   American Heart Journal·2026·n=1,270

   <h4>Background</h4>The periprocedural management of elective invasive coronary angiography (ICA) or percutaneous coronary intervention (PCI) of patients using direct oral anticoagulation (DOAC) remains debated. This trial aims to evaluate…

6. 06

   2% Lidocaine Spray vs. 2% Lidocaine Viscous for Head and Neck Cancer with Chemoradiation Mucositis

   Journal of Pain and Symptom Management·2026·n=60

   <h4>Objectives</h4>The use of 2% lidocaine oral viscous is constrained by its inconvenience of portability, coupled with difficulty swallowing in some cases, and its unpleasant taste. This study aimed to compare the effects of 2%…

7. 07

   Outcomes with limus-coated vs. paclitaxel-coated balloons for percutaneous coronary intervention: An updated meta-analysis and reconstructed time-to-event analysis of randomized controlled trials

   Heart &amp; Lung·2026

   <h4>Background</h4>Paclitaxel drug-coated balloons (DCBs) are an established option for treating coronary in-stent restenosis (ISR) and small vessel disease. However, randomized controlled trials (RCTs) comparing limus-DCBs with…

8. 08

   Efficacy and safety of cyanoacrylate ablation vs endovenous radiofrequency ablation for varicose veins in chronic great saphenous vein insufficiency: A systematic review and meta-analysis

   Journal of Vascular Surgery: Venous and Lymphatic Disorders·2026

   <h4>Objective</h4>Endovenous radiofrequency ablation (RFA) and cyanoacrylate ablation (CA) are widely used for the treatment of chronic great saphenous vein (GSV) insufficiency. Compared with traditional surgery, both modalities have…

9. 09

   Interaction of basal ganglia infarction with bridging therapy vs mechanical thrombectomy on parenchymal hemorrhage: A secondary analysis of the DIRECT-MT trial

   Journal of Clinical Neuroscience·2026·n=657

   Importance Hemorrhagic transformation (HT), particularly parenchymal hematoma (PH), is a critical complication of reperfusion therapy for acute ischemic stroke, potentially offsetting the benefits of mechanical thrombectomy (MT). Whether…

10. 10

    Impact of hypofractionated radiotherapy schedules on local control in early breast cancer: A five-year study of boost vs. non-boost protocols

    Applied Radiation and Isotopes·2026·n=270

    <h4>Background</h4>Hypofractionated radiotherapy (HFRT) is a standard treatment following breast-conserving surgery (BCS) for early breast cancer, yet the role of a tumor bed boost in HFRT protocols remains underexplored, particularly in…