Back to Recovery
Recovery

Cold PlungeEvidence & Dosage

3–15 min in <15°C — anti-inflammatory, but can blunt hypertrophy.

Studies last updated

Evidence at a glance

Total studies
452
With abstract
48
Meta / Systematic / RCT
136
Highly cited
50
Publication years
1987–2026

Cold Plunge in the context of Recovery

This topic is part of our "Recovery" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

Go to Recovery

Top studies on Cold Plunge

Ranked by influential-citation count and publication year.

  1. Prediction of good neurological outcome in comatose survivors of cardiac arrest: a systematic review.

    Intensive Care Med2022n=37Systematic Review154 influential citations

    <h4>Purpose</h4>To assess the ability of clinical examination, blood biomarkers, electrophysiology or neuroimaging assessed within 7 days from return of spontaneous circulation (ROSC) to predict good neurological outcome, defined as no,…

  2. Hypoxic-Ischemic Encephalopathy: Pathogenesis and Promising Therapies.

    Mol Neurobiol2025Systematic Review151 influential citations

    Hypoxic-ischemic encephalopathy (HIE) is a brain lesion caused by inadequate blood supply and oxygen deprivation, often occurring in neonates. It has emerged as a grave complication of neonatal asphyxia, leading to chronic neurological…

  3. Neurologic Prognostication After Cardiac Arrest Using Brain Biomarkers: A Systematic Review and Meta-analysis.

    JAMA Neurol2022n=10,567Meta-Analysis87 influential citations

    <h4>Importance</h4>Brain injury biomarkers released into circulation from the injured neurovascular unit are important prognostic tools in patients with cardiac arrest who develop hypoxic ischemic brain injury (HIBI) after return of…

  4. Effects of Cold-Water Immersion Compared with Other Recovery Modalities on Athletic Performance Following Acute Strenuous Exercise in Physically Active Participants: A Systematic Review, Meta-Analysis, and Meta-Regression.

    Sports Med2023n=28meta77 influential citations

    BACKGROUND: Studies investigating the effects of common recovery modalities following acute strenuous exercise have reported mixed results. OBJECTIVES: This systematic review with meta-analysis and meta-regression compared the effects of…

    Finding: Cold-water immersion was superior to other recovery methods for recovering from muscle soreness.

  5. Established focal therapy-HIFU, IRE, or cryotherapy-where are we now?-a systematic review and meta-analysis.

    Prostate Cancer Prostatic Dis2025n=49Meta-Analysis76 influential citations

    <h4>Introduction</h4>Focal Therapy (FT) is a treatment option for the treatment of limited volume clinically significant prostate cancer (csPCa). We aim to systematically review outcomes of established FT modalities to assess the…

  6. Cryotherapy following total knee replacement.

    Cochrane Database Syst Rev2023n=183systematic69 influential citations

    BACKGROUND: Total knee replacement (TKR) is a common intervention for people with end-stage symptomatic knee osteoarthritis, resulting in significant improvements in pain, function and quality of life within three to six months. It is,…

  7. Comparison of cooling methods to induce and maintain normo- and hypothermia in intensive care unit patients: a prospective intervention study.

    Critical care (London, England)2007n=5067 influential citations

    <h4>Background</h4>Temperature management is used with increased frequency as a tool to mitigate neurological injury. Although frequently used, little is known about the optimal cooling methods for inducing and maintaining controlled…

  8. Effects of cold water immersion after exercise on fatigue recovery and exercise performance--meta analysis.

    Front Physiol2023n=419systematic63 influential citations

    Cold water immersion (CWI) is very popular as a method reducing post-exercise muscle stiffness, eliminating fatigue, decreasing exercise-induced muscle damage (EIMD), and recovering sports performance. However, there are conflicting…

  9. The effects of cold exposure (cold water immersion, whole- and partial- body cryostimulation) on cardiovascular and cardiac autonomic control responses in healthy individuals: A systematic review, meta-analysis and meta-regression.

    J Therm Biol2024n=27meta62 influential citations

    BACKGROUND: Cryostimulation and cold-water immersion (CWI) have recently gained widespread attention due to their association with changes in cardiovascular and cardiac autonomic control responses. Therefore, the aim of the present…

  10. Clinical outcomes of mild versus moderate hypothermic circulatory arrest with antegrade cerebral perfusion in adult aortic arch surgery: A systematic review and meta-analysis.

    Perfusion2024n=305Meta-Analysis57 influential citations

    <h4>Objectives</h4>In adult aortic arch surgery, moderate hypothermic circulatory arrest (HCA) with selective antegrade cerebral perfusion (SACP) (MoHACP) is widely used, but the application of mild HCA with SACP (MiHACP) is still…

Frequently asked

What dosage was studied?
• Clinical examination, blood biomarkers, electrophysiology, or neuroimaging assessed within 7 days after ROSC • Hypothermia therapy; drug therapy and stem cell therapy discussed as adjunctive treatments (not reported) • Bloodborne brain injury biomarkers for neurologic prognostication (neurone-specific enolase, S100B, GFAP, neurofilament light, tau, UCH-L1)
Which population does the evidence apply to?
Most studies investigated: unknown; patient.
Are there safety considerations for Cold Plunge?
• Not reported • Hypothermia is described as the current standard therapy and only partial neuroprotection is noted. • No adverse events of drug or stem cell adjuncts are reported in the abstract. • Not reported in abstract

Related articles

More topics in Recovery

Related topics from other worlds