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Longevity

InflammagingStudienlage & Dosis

Chronisch niedriggradige Entzündung im Alter — Treiber und Gegenmaßnahmen.

Studienlage in Zahlen

Studien gesamt
971
Mit Abstract
49
Meta / Systematic / RCT
0
Häufig zitiert
12
Erscheinungsjahre
1993–2026

Inflammaging im Kontext von Longevity

Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

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Top-Studien zu Inflammaging

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

  1. Nonuniversality of inflammaging across human populations.

    Nature aging2025145 einflussreiche Zitationen

    Inflammaging, an age-associated increase in chronic inflammation, is considered a hallmark of aging. However, there is no consensus approach to measuring inflammaging based on circulating cytokines. Here we assessed whether an inflammaging…

  2. Inflammaging as a target for healthy ageing.

    Age Ageing2023review120 einflussreiche Zitationen

    Life expectancy has been on the rise for the past few decades, but healthy life expectancy has not kept pace, leading to a global burden of age-associated disorders. Advancing age is accompanied by a chronic increase in basal systemic…

  3. Age-related bone diseases: Role of inflammaging.

    Journal of autoimmunity2024108 einflussreiche Zitationen

    Bone aging is characterized by an imbalance in the physiological and pathological processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis, resulting in exacerbated bone loss and the development of age-related bone…

  4. The 3 I's of immunity and aging: immunosenescence, inflammaging, and immune resilience.

    Front Aging2024review100 einflussreiche Zitationen

    As we age, our immune system's ability to effectively respond to pathogens declines, a phenomenon known as immunosenescence. This age-related deterioration affects both innate and adaptive immunity, compromising immune function and leading…

  5. Inflammaging and Brain Aging.

    International journal of molecular sciences202498 einflussreiche Zitationen

    Progress made by the medical community in increasing lifespans comes with the costs of increasing the incidence and prevalence of age-related diseases, neurodegenerative ones included. Aging is associated with a series of morphological…

  6. Mechanisms Underlying Vascular Inflammaging: Current Insights and Potential Treatment Approaches.

    Aging and disease202444 einflussreiche Zitationen

    Inflammaging refers to chronic, low-grade inflammation that becomes more common with age and plays a central role in the pathophysiology of various vascular diseases. Key inflammatory mediators involved in inflammaging contribute to…

  7. Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives.

    Cell reports. Medicine2025D40 einflussreiche Zitationen

    Both aging and systemic inflammation are major risk factors for cardiovascular disease. This review summarizes the interrelationship of aging and inflammation-known as inflammaging-and the consequences for cardiovascular health. We discuss…

  8. Autophagy Controls Acquisition of Aging Features in Macrophages.

    Journal of innate immunity201539 einflussreiche Zitationen

    Macrophages provide a bridge linking innate and adaptive immunity. An increased frequency of macrophages and other myeloid cells paired with excessive cytokine production is commonly seen in the aging immune system, known as…

  9. Exploring the complex relations between inflammation and aging (inflamm-aging): anti-inflamm-aging remodelling of inflamm- aging, from robustness to frailty.

    Inflammation research : official journal of the European Histamine Research Society ... [et al.]2008E24 einflussreiche Zitationen

    "Inflamm-aging" denotes the up-regulation of certain pro-inflammatory cytokines at older ages, and associated chronic diseases. It is well known that blood levels of cortisol also increase with age, an increase commonly considered to be…

  10. Immunosenescence and inflammaging: Mechanisms and modulation through diet and lifestyle.

    Frontiers in immunology2025D23 einflussreiche Zitationen

    Aging is associated with profound alterations in the immune system, characterized by immunosenescence and inflammaging, which together compromise host defense, promote chronic low-grade inflammation, and contribute to the development of…

Weitere Themen in Longevity

Zone 2

Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.

Rapamycin

mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.

AMPK Activators

Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.

ApoB

Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.

Autophagie

Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.

Berberin

Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.

Biologisches Alter

GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.

Caloric Restriction

CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.

Krebsfrüherkennung

Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).

Zelluläre Seneszenz

„Zombie-Zellen", SASP, Senolytika-Ansätze.

Kollagen

Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.

Demenz-Prävention

Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.

DEXA-Knochendichte

DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.

Epigenetische Uhren

Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.

Epigenetik

DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.

Exosomen

Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.

Genetiktests

Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.

Glucosamine

Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.

Glycin

Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.

Griffkraft

Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.

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