InflammagingStudienlage & Dosis
Chronisch niedriggradige Entzündung im Alter — Treiber und Gegenmaßnahmen.
Studienlage in Zahlen
- Studien gesamt
- 971
- Mit Abstract
- 49
- Meta / Systematic / RCT
- 0
- Häufig zitiert
- 12
- Erscheinungsjahre
- 1993–2026
Inflammaging im Kontext von Longevity
Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.
Zur Welt LongevityTop-Studien zu Inflammaging
Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.
Nonuniversality of inflammaging across human populations.
Nature aging2025145 einflussreiche ZitationenInflammaging, an age-associated increase in chronic inflammation, is considered a hallmark of aging. However, there is no consensus approach to measuring inflammaging based on circulating cytokines. Here we assessed whether an inflammaging…
Inflammaging as a target for healthy ageing.
Age Ageing2023review120 einflussreiche ZitationenLife expectancy has been on the rise for the past few decades, but healthy life expectancy has not kept pace, leading to a global burden of age-associated disorders. Advancing age is accompanied by a chronic increase in basal systemic…
Age-related bone diseases: Role of inflammaging.
Journal of autoimmunity2024108 einflussreiche ZitationenBone aging is characterized by an imbalance in the physiological and pathological processes of osteogenesis, osteoclastogenesis, adipogenesis, and chondrogenesis, resulting in exacerbated bone loss and the development of age-related bone…
The 3 I's of immunity and aging: immunosenescence, inflammaging, and immune resilience.
Front Aging2024review100 einflussreiche ZitationenAs we age, our immune system's ability to effectively respond to pathogens declines, a phenomenon known as immunosenescence. This age-related deterioration affects both innate and adaptive immunity, compromising immune function and leading…
Inflammaging and Brain Aging.
International journal of molecular sciences202498 einflussreiche ZitationenProgress made by the medical community in increasing lifespans comes with the costs of increasing the incidence and prevalence of age-related diseases, neurodegenerative ones included. Aging is associated with a series of morphological…
Mechanisms Underlying Vascular Inflammaging: Current Insights and Potential Treatment Approaches.
Aging and disease202444 einflussreiche ZitationenInflammaging refers to chronic, low-grade inflammation that becomes more common with age and plays a central role in the pathophysiology of various vascular diseases. Key inflammatory mediators involved in inflammaging contribute to…
Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives.
Cell reports. Medicine2025D40 einflussreiche ZitationenBoth aging and systemic inflammation are major risk factors for cardiovascular disease. This review summarizes the interrelationship of aging and inflammation-known as inflammaging-and the consequences for cardiovascular health. We discuss…
Autophagy Controls Acquisition of Aging Features in Macrophages.
Journal of innate immunity201539 einflussreiche ZitationenMacrophages provide a bridge linking innate and adaptive immunity. An increased frequency of macrophages and other myeloid cells paired with excessive cytokine production is commonly seen in the aging immune system, known as…
Exploring the complex relations between inflammation and aging (inflamm-aging): anti-inflamm-aging remodelling of inflamm- aging, from robustness to frailty.
Inflammation research : official journal of the European Histamine Research Society ... [et al.]2008E24 einflussreiche Zitationen"Inflamm-aging" denotes the up-regulation of certain pro-inflammatory cytokines at older ages, and associated chronic diseases. It is well known that blood levels of cortisol also increase with age, an increase commonly considered to be…
Immunosenescence and inflammaging: Mechanisms and modulation through diet and lifestyle.
Frontiers in immunology2025D23 einflussreiche ZitationenAging is associated with profound alterations in the immune system, characterized by immunosenescence and inflammaging, which together compromise host defense, promote chronic low-grade inflammation, and contribute to the development of…
Weitere Themen in Longevity
Zone 2
Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.
Rapamycin
mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.
AMPK Activators
Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.
ApoB
Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.
Autophagie
Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.
Berberin
Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.
Biologisches Alter
GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.
Caloric Restriction
CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.
Krebsfrüherkennung
Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).
Zelluläre Seneszenz
„Zombie-Zellen", SASP, Senolytika-Ansätze.
Kollagen
Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.
Demenz-Prävention
Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.
DEXA-Knochendichte
DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.
Epigenetische Uhren
Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.
Epigenetik
DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.
Exosomen
Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.
Genetiktests
Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.
Glucosamine
Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.
Glycin
Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.
Griffkraft
Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.
Verwandte Themen aus anderen Welten
DHEA
DHEA als Vorläuferhormon für hormonelle Balance und Vitalität.
GLP-1
Glucagon-like Peptide 1 — Inkretin, Sättigung, Blutzucker, Semaglutid-Wirkmechanismus.
IGF-1
Insulin-like Growth Factor — Wachstum, Anabolismus, Longevity-Trade-off.
PCOS
Polyzystisches Ovarial-Syndrom — Insulinresistenz, Androgene, Lifestyle.
Rezeptorsensitivität
Up-/Downregulation, Toleranz, Hormonresistenz als Phänomen.
Thyroid Function
Schilddrüsenfunktion für Stoffwechsel, Energie und mentale Klarheit.