ExosomenStudienlage & Dosis
Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.
Studienlage in Zahlen
- Studien gesamt
- 1.000
- Mit Abstract
- 47
- Meta / Systematic / RCT
- 0
- Häufig zitiert
- 1
- Erscheinungsjahre
- 1999–2026
Exosomen im Kontext von Longevity
Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.
Zur Welt LongevityTop-Studien zu Exosomen
Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.
Therapeutic Potential of Extracellular Vesicles (Exosomes) Derived From Platelet-Rich Plasma: A Literature Review.
J Cosmet Dermatol2025n=12review40 einflussreiche ZitationenBACKGROUND: There are exciting advances in the field of exosomes research as a potential regenerative therapy. Platelet-rich plasma represents an abundant source of exosomes. AIM: To present evidence on the use of platelet-rich…
A synergistic strategy involving reverse-adaptation and engineered MSC exosomes against ferroptosis in osteoarthritis
Biomaterials20261 einflussreiche ZitationenOsteoarthritis (OA) progression is driven by persistent oxidative stress and ferroptosis, which erode chondrocyte viability and extracellular matrix integrity. Although mesenchymal stem cell-derived exosomes (MSC-EXO) hold regenerative…
Synergistic regeneration of cartilage and bone using synovial fluid-derived MSCs and exosomes: A novel therapeutic strategy for osteoarthritis
Colloids and Surfaces B: Biointerfaces2026n=30Osteoarthritis (OA) is the most common and progressive joint disorder, characterized by the slow breakdown of cartilage and the underlying bone. The leading cause of OA is age-related wear and tear of joint cartilage, often worsened by…
ADMSC-derived exosomes promote diabetic wound healing by inhibiting neutrophil extracellular traps formation through delivering miR-92a-1-5p
Archives of Biochemistry and Biophysics2026Adipose-derived mesenchymal stem cell-derived exosomes (ADMSC-ex) have demonstrated remarkable efficacy in promoting diabetic wound healing. However, the underlying mechanisms remain largely elusive. In this study, we showed the healing…
A prognostic exosome-related mRNAs risk signature correlates with the immune microenvironment in breast cancer.
Discover oncology2026EBreast cancer (BC) represents one of the most prevalent malignancies among women worldwide. Despite substantial advances in diagnostic and therapeutic modalities and pharmacological interventions in recent years, the accurate assessment of…
Human umbilical cord mesenchymal stromal cells-derived exosomes from MSCs pretreated with inflammatory factors attenuate renal injury of diabetic mice by regulating macrophage polarization.
Clinical science (London, England : 1979)2026EDiabetic nephropathy (DN), a major complication of diabetes mellitus (DM), is characterized by severe clinical manifestations, impaired quality of life, and a high risk of progression to end-stage renal disease, underscoring the urgent…
Intelligent plant exosomes synergize miRNAs and cisplatin for spatiotemporally precise multimodal treatment for TNBC with high safety
Bioactive Materials2026Triple-negative breast cancer (TNBC) lacks common receptors and exhibits aggressive behavior, limiting treatment options due to drug resistance and systemic toxicity. TNBC chemotherapy is hindered by poor tumor targeting, drug resistance,…
CircEif3c/miR-96–5p/PHF20L1/MEOX2 axis in perivascular preadipocyte exosomes mediates fibroblast dysfunction and vascular remodeling
Non-coding RNA Research2026<h4>Background</h4>Diabetes mellitus is a major modifiable risk factor for atherosclerotic cardiovascular disease and pathological vascular remodeling. During chronic hyperglycemia, exosomes serve as essential nanocarriers that coordinate…
Milk exosomes delivery of KPT-330 alleviates gastrointestinal adverse reactions and provides effective anti-diffuse large B-cell lymphoma therapy
Colloids and Surfaces B: Biointerfaces2026The FDA granted accelerated approval to KPT-330 (selinexor) for the treatment of patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL). However, 80% of patients experienced gastrointestinal toxicity. Milk exosomes…
Plant-derived exosomes: Structure, isolation, biological functions, and therapeutic potentials
Tissue and Cell2026Exosomes are small extracellular vesicles that play a role in intercellular communication by transporting bioactive lipids, proteins, and nucleic acids. While animal- derived exosomes have been extensively studied, plant-derived exosomes…
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Weitere Themen in Longevity
Zone 2
Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.
Rapamycin
mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.
AMPK Activators
Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.
ApoB
Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.
Autophagie
Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.
Berberin
Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.
Biologisches Alter
GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.
Caloric Restriction
CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.
Krebsfrüherkennung
Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).
Zelluläre Seneszenz
„Zombie-Zellen", SASP, Senolytika-Ansätze.
Kollagen
Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.
Demenz-Prävention
Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.
DEXA-Knochendichte
DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.
Epigenetische Uhren
Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.
Epigenetik
DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.
Genetiktests
Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.
Glucosamine
Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.
Glycin
Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.
Griffkraft
Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.
Hallmarks of Aging
Genomische Instabilität, Telomer-Verkürzung, epigenetische Veränderungen, etc.
Verwandte Themen aus anderen Welten
Zyklus-Tracking
Menstruationszyklus, Symptome, Fertilität — Apps und Wearables.
Nierenwerte
Kreatinin, Harnstoff, eGFR, Cystatin C — Nierenfunktion bewerten.
VO2max
Maximale Sauerstoffaufnahme — stärkster Longevity-Prädiktor.
Cortisol Management
HPA-Achse, Stress-Kurve, Adaptogene und gesunder Tagesrhythmus.
Freies Testosteron
Bioverfügbares T, SHBG-Einfluss, klinische Relevanz.
Hormonsystem
Endokrine Drüsen, Hormonachsen, Feedback-Loops — wie Hormone Verhalten und Stoffwechsel steuern.