Longevity

BerberinStudienlage & Dosis

Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.

Studien zuletzt aktualisiert 15. Mai 2026

Studienlage in Zahlen

Studien gesamt: 1.000
Mit Abstract: 49
Meta / Systematic / RCT: 135
Häufig zitiert: 50
Erscheinungsjahre: 1960–2026

Berberin im Kontext von Longevity

Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

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Top-Studien zu Berberin

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Berberine is a novel cholesterol-lowering drug working through a unique mechanism distinct from statins.
Nat Med2004Clinical Trial200 einflussreiche Zitationen
We identify berberine (BBR), a compound isolated from a Chinese herb, as a new cholesterol-lowering drug. Oral administration of BBR in 32 hypercholesterolemic patients for 3 months reduced serum cholesterol by 29%, triglycerides by 35%…
Efficacy of berberine in patients with type 2 diabetes mellitus.
Metabolism2008n=84rct160 einflussreiche Zitationen
Berberine has been shown to regulate glucose and lipid metabolism in vitro and in vivo. This pilot study was to determine the efficacy and safety of berberine in the treatment of type 2 diabetes mellitus patients. In study A, 36 adults…
Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipemia and hypertension.
J Ethnopharmacol2015n=256meta133 einflussreiche Zitationen
ETHNOPHARMACOLOGICAL RELEVANCE: Berberine, extracted from Coptis Root and Phellodendron Chinese, has been frequently used for the adjuvant treatment of type 2 diabetes mellitus, hyperlipidemia, and hypertension in China. Safety and…
Treatment of type 2 diabetes and dyslipidemia with the natural plant alkaloid berberine.
J Clin Endocrinol Metab2008n=116rct119 einflussreiche Zitationen
CONTEXT: Berberine, a natural plant alkaloid, is usually used as an antibiotic drug. The potential glucose-lowering effect of berberine was noted when it was used for diarrhea in diabetic patients. In vitro and in vivo studies have then…
Berberine and health outcomes: An umbrella review.
Phytother Res2023n=11systematic103 einflussreiche Zitationen
Berberine is a plant extract widely used in clinical practice. This review aimed to summarize and to grade the available evidence on the association between berberine consumption and health-related outcomes. The PubMed, Cochrane Library,…
The clinical efficacy and safety of berberine in the treatment of non-alcoholic fatty liver disease: a meta-analysis and systematic review.
J Transl Med2024n=811Meta-Analysis103 einflussreiche Zitationen
<h4>Background</h4>Non-alcoholic fatty liver disease (NAFLD) is becoming increasingly prevalent worldwide, emerging as a significant health issue on a global scale. Berberine exhibits potential for treating NAFLD, but clinical evidence…
Berberine lowers blood glucose in type 2 diabetes mellitus patients through increasing insulin receptor expression.
Metabolism2010rct93 einflussreiche Zitationen
Our previous work demonstrated that berberine (BBR) increases insulin receptor (InsR) expression and improves glucose utility both in vitro and in animal models. Here, we study the InsR-up-regulating and glucose-lowering activities of BBR…
Combined berberine and probiotic treatment as an effective regimen for improving postprandial hyperlipidemia in type 2 diabetes patients: a double blinded placebo controlled randomized study.
Gut Microbes2022n=365rct86 einflussreiche Zitationen
Non-fasting lipidemia (nFL), mainly contributed by postprandial lipidemia (PL), has recently been recognized as an important cardiovascular disease (CVD) risk as fasting lipidemia (FL). PL serves as a common feature of dyslipidemia in Type…
Berberine Ursodeoxycholate for the Treatment of Type 2 Diabetes: A Randomized Clinical Trial.
JAMA Netw Open2025n=113rct83 einflussreiche Zitationen
IMPORTANCE: Few of the available therapies for type 2 diabetes (T2D) comprehensively address disease burden beyond glycemic control. Examining whether berberine ursodeoxycholate (HTD1801), a first-in-class gut-liver anti-inflammatory…
A systematic review of the anticancer properties of berberine, a natural product from Chinese herbs.
Anticancer Drugs2009Systematic Review79 einflussreiche Zitationen
Natural products represent a rich reservoir of potential small chemical molecules exhibiting antiproliferation and anticancer properties. An example is berberine, a protoberberine alkaloid widely distributed in medical plants used in…

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Welche Dosierung wurde in den Studien untersucht?

• Berberine (Not stated in excerpt; metformin comparator dose 0.5 g t.i.d.) • Berberine (alone or combined with lifestyle intervention/oral hypoglycemics/oral lipid-lowering drugs/oral hypotensor) (Not reported)

Gibt es Sicherheitshinweise zu Berberin?

• 20 (34.5%) patients had transient gastrointestinal adverse effects. • No functional liver damage was observed. • No functional kidney damage was observed. • No serious adverse reactions were reported across 27 trials.

Studienlage in Zahlen

Berberin im Kontext von Longevity

Top-Studien zu Berberin

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