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Longevity

KollagenStudienlage & Dosis

Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.

Studienlage in Zahlen

Studien gesamt
1.000
Mit Abstract
38
Meta / Systematic / RCT
0
Häufig zitiert
4
Erscheinungsjahre
1950–2026

Kollagen im Kontext von Longevity

Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Longevity

Top-Studien zu Kollagen

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

  1. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus.

    American journal of ophthalmology2003n=22200 einflussreiche Zitationen

    <h4>Purpose</h4>In animal eyes, a significant increase in corneal biomechanical stiffness has been found after collagen crosslinking by combined riboflavin/ultraviolet-A (UVA) treatment. The aim of the present study was to evaluate the…

  2. Metabolic dysregulation and adipose tissue fibrosis: role of collagen VI.

    Molecular and cellular biology2009200 einflussreiche Zitationen

    Adipocytes are embedded in a unique extracellular matrix whose main function is to provide mechanical support, in addition to participating in a variety of signaling events. During adipose tissue expansion, the extracellular matrix…

  3. The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis.

    Proceedings of the National Academy of Sciences of the United States of America2000132 einflussreiche Zitationen

    The therapeutic potential of cannabidiol (CBD), the major nonpsychoactive component of cannabis, was explored in murine collagen-induced arthritis (CIA). CIA was elicited by immunizing DBA/1 mice with type II collagen (CII) in complete…

  4. Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro.

    Proceedings of the National Academy of Sciences1986

    Transforming growth factor type beta (TGF-beta), when injected subcutaneously in newborn mice, causes formation of granulation tissue (induction of angiogenesis and activation of fibroblasts to produce collagen) at the site of injection.…

  5. Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

    Journal of Biological Chemistry1986

    We have examined whether the extracellular matrix is a biochemical target for transforming growth factor-beta (TGFbeta). We find that TGFbeta increases the expression of the major extracellular matrix proteins, fibronectin and collagen.…

  6. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels

    Cell1982

    The differentiated phenotype of rabbit articular chondrocytes consists primarily of type II collagen and cartilage-specific proteoglycan. During serial monolayer culture this phenotype is lost and replaced by a complex collagen phenotype…

  7. Electrospinning of Collagen Nanofibers

    Biomacromolecules2002

    Electrospinning is a fabrication process that uses an electric field to control the deposition of polymer fibers onto a target substrate. This electrostatic processing strategy can be used to fabricate fibrous polymer mats composed of…

  8. The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

    Biomaterials2009

    In the literature there are conflicting reports on the optimal scaffold mean pore size required for successful bone tissue engineering. This study set out to investigate the effect of mean pore size, in a series of…

  9. Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility

    The Journal of Cell Biology1997

    Decorin is a member of the expanding group of widely distributed small leucine-rich proteoglycans that are expected to play important functions in tissue assembly. We report that mice harboring a targeted disruption of the decorin gene are…

  10. Collagen density promotes mammary tumor initiation and progression

    BMC Medicine2008

    <h4>Background</h4>Mammographically dense breast tissue is one of the greatest risk factors for developing breast carcinoma. Despite the strong clinical correlation, breast density has not been causally linked to tumorigenesis, largely…

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Weitere Themen in Longevity

Zone 2

Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.

Rapamycin

mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.

AMPK Activators

Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.

ApoB

Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.

Autophagie

Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.

Berberin

Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.

Biologisches Alter

GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.

Caloric Restriction

CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.

Krebsfrüherkennung

Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).

Zelluläre Seneszenz

„Zombie-Zellen", SASP, Senolytika-Ansätze.

Demenz-Prävention

Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.

DEXA-Knochendichte

DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.

Epigenetische Uhren

Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.

Epigenetik

DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.

Exosomen

Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.

Genetiktests

Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.

Glucosamine

Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.

Glycin

Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.

Griffkraft

Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.

Hallmarks of Aging

Genomische Instabilität, Telomer-Verkürzung, epigenetische Veränderungen, etc.

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