Longevity

Demenz-PräventionStudienlage & Dosis

Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.

Studienlage in Zahlen

Studien gesamt: 1.000
Mit Abstract: 43
Meta / Systematic / RCT: 5
Häufig zitiert: 28
Erscheinungsjahre: 1968–2026

Demenz-Prävention im Kontext von Longevity

Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Longevity

Top-Studien zu Demenz-Prävention

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial.
Lancet (London, England)2015n=1.260200 einflussreiche Zitationen
<h4>Background</h4>Modifiable vascular and lifestyle-related risk factors have been associated with dementia risk in observational studies. In the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability…
An active and socially integrated lifestyle in late life might protect against dementia.
The Lancet. Neurology2004200 einflussreiche Zitationen
The recent availability of longitudinal data on the possible association of different lifestyles with dementia and Alzheimer's disease (AD) allow some preliminary conclusions on this topic. This review systematically analyses the published…
Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease.
Archives of neurology2005n=1.449200 einflussreiche Zitationen
<h4>Background</h4>Vascular risk factors play a role in the development of dementia, including Alzheimer disease (AD). However, little is known about the effect of body mass index and clustering of vascular risk factors on the development…
Trial of the MIND Diet for Prevention of Cognitive Decline in Older Persons.
The New England journal of medicine2023n=1.929200 einflussreiche Zitationen
<h4>Background</h4>Findings from observational studies suggest that dietary patterns may offer protective benefits against cognitive decline, but data from clinical trials are limited. The Mediterranean-DASH Intervention for…
Association of Factors With Elevated Amyloid Burden in Clinically Normal Older Individuals.
JAMA neurology2020n=4.486159 einflussreiche Zitationen
<h4>Importance</h4>The Anti-Amyloid Treatment in Asymptomatic Alzheimer disease (A4) Study is an ongoing prevention trial in clinically normal older individuals with evidence of elevated brain amyloid. The large number of participants…
Japan-Multimodal Intervention Trial for the Prevention of Dementia: A randomized controlled trial.
Alzheimer's & dementia : the journal of the Alzheimer's Association2024n=531143 einflussreiche Zitationen
<h4>Introduction</h4>We examined the efficacy of a multidomain intervention in preventing cognitive decline among Japanese older adults with mild cognitive impairment (MCI).<h4>Methods</h4>Participants aged 65-85 years with MCI were…
Association of Daily Step Count and Intensity With Incident Dementia in 78 430 Adults Living in the UK.
JAMA neurology2022n=430135 einflussreiche Zitationen
Importance Step-based recommendations may be appropriate for dementia-prevention guidelines. However, the association of step count and intensity with dementia incidence is unknown. Objective To examine the dose-response association…
Physical activity and exercise for the prevention and management of mild cognitive impairment and dementia: a collaborative international guideline.
European geriatric medicine202399 einflussreiche Zitationen
Background Physical activity and exercise have been suggested as effective interventions for the prevention and management of mild cognitive impairment (MCI) and dementia, but there are no international guidelines. Objectives To create a…
Fruit and vegetable juices and Alzheimer's disease: the Kame Project.
The American journal of medicine200696 einflussreiche Zitationen
<h4>Background</h4>Growing evidence suggests that oxidative damage caused by the beta-amyloid peptide in the pathogenesis of Alzheimer's disease may be hydrogen peroxide mediated. Many polyphenols, the most abundant dietary antioxidants,…
Advances in the prevention of Alzheimer's disease and dementia.
Journal of internal medicine2014n=30.00084 einflussreiche Zitationen
<h4>Background</h4>Definitions and diagnostic criteria for all medical conditions are regularly subjected to reviews and revisions as knowledge advances. In the field of Alzheimer's disease (AD) research, it has taken almost three decades…

Häufige Fragen

Welche Dosierung wurde in den Studien untersucht?

• multidomain intervention (diet, exercise, cognitive training, vascular risk monitoring)

Gibt es Sicherheitshinweise zu Demenz-Prävention?

• Adverse events occurred in 46 (7%) participants in the intervention group compared with six (1%) participants in the control group; the most common adverse event was musculoskeletal pain (32 [5%] individuals for intervention vs no individuals for control).