Biologisches AlterStudienlage & Dosis
GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.
Studienlage in Zahlen
- Studien gesamt
- 908
- Mit Abstract
- 37
- Meta / Systematic / RCT
- 1
- Häufig zitiert
- 7
- Erscheinungsjahre
- 1947–2027
Biologisches Alter im Kontext von Longevity
Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.
Zur Welt LongevityTop-Studien zu Biologisches Alter
Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.
Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging.
Proceedings of the National Academy of Sciences of the United States of America2001n=1.189200 einflussreiche ZitationenAllostatic load (AL) has been proposed as a new conceptualization of cumulative biological burden exacted on the body through attempts to adapt to life's demands. Using a multisystem summary measure of AL, we evaluated its capacity to…
Accelerated biological aging and risk of depression and anxiety: evidence from 424,299 UK Biobank participants.
Nature communications2023200 einflussreiche ZitationenTheory predicts that biological processes of aging may contribute to poor mental health in late life. To test this hypothesis, we evaluated prospective associations between biological age and incident depression and anxiety in 424,299 UK…
A metabolomic profile of biological aging in 250,341 individuals from the UK Biobank.
Nature communications2024n=95.372134 einflussreiche ZitationenThe metabolomic profile of aging is complex. Here, we analyse 325 nuclear magnetic resonance (NMR) biomarkers from 250,341 UK Biobank participants, identifying 54 representative aging-related biomarkers associated with all-cause mortality.…
Dietary flavonoids intake contributes to delay biological aging process: analysis from NHANES dataset.
Journal of translational medicine202388 einflussreiche ZitationenBackground Diet may influence biological aging and the discrepancy (∆age) between a subject’s biological age (BA) and chronological age (CA). We aimed to investigate the correlation of dietary flavonoids with the ∆age of organs (heart,…
Systemic inflammation and biological aging in the Health and Retirement Study.
GeroScience2023n=3.11376 einflussreiche ZitationenChronic, low-level systemic inflammation associated with aging, or inflammaging, is a risk factor for several chronic diseases and mortality. Using data from the Health and Retirement Study, we generated a continuous latent variable for…
Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis.
J Gerontol A Biol Sci Med Sci2017n=220RCT58 einflussreiche ZitationenBiological aging measures have been proposed as proxies for extension of healthy life span in trials of geroprotective therapies that aim to slow aging. Several methods to measure biological aging show promise but it is not known if these…
Adverse events in both childhood and adulthood are associated with molecular, clinical and functional markers of ageing.
BMC medicine2026EAdverse events across the lifespan have been linked to poorer health outcomes, but the biological mechanisms remain unclear. The aim of this study was to quantify the independent and joint associations of adversity experienced in childhood…
Synergistic impact of rest-activity circadian rhythms and physical activity on all-cause and cardiovascular mortality.
The journals of gerontology. Series A, Biological sciences and medical sciences2026n=6.621EThis study investigated the independent and joint associations of rest-activity circadian rhythms (RACRs) and physical activity (PA) with all-cause and cardiovascular mortality, and explored the potential role of accelerated biological…
Depression and biological aging: Unexpected vulnerability in relatively advantaged social risk profile group.
Acta psychologica2026n=18.787<h4>Background</h4>Depression has significantly associated with biological aging. Although lower social status is generally linked to increased vulnerability to aging, the biological impact of depression may differ according to social…
Epigenetic Age Feedback as a Catalyst for Sustained Lifestyle Change: One-Year Results from the EU iHelp Study.
Epigenomes2026n=178<h4>Background</h4>Sustaining long-term lifestyle change remains a major challenge in preventive health. Epigenetic clocks offer a dynamic, modifiable measure of biological ageing that may enhance motivation when returned to…
Häufige Fragen
Gibt es Sicherheitshinweise zu Biologisches Alter?
Weitere Themen in Longevity
Zone 2
Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.
Rapamycin
mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.
AMPK Activators
Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.
ApoB
Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.
Autophagie
Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.
Berberin
Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.
Caloric Restriction
CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.
Krebsfrüherkennung
Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).
Zelluläre Seneszenz
„Zombie-Zellen", SASP, Senolytika-Ansätze.
Kollagen
Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.
Demenz-Prävention
Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.
DEXA-Knochendichte
DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.
Epigenetische Uhren
Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.
Epigenetik
DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.
Exosomen
Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.
Genetiktests
Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.
Glucosamine
Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.
Glycin
Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.
Griffkraft
Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.
Hallmarks of Aging
Genomische Instabilität, Telomer-Verkürzung, epigenetische Veränderungen, etc.
Verwandte Themen aus anderen Welten
Beetroot / Nitrate
NO-Synthase-Bypass, Ausdauer und Höhenanpassung.
EAAs / BCAAs
Muskelproteinsynthese, Anti-Catabolisch und Leucin-Schwellenwert.
Hypertrophie
Muskel-Wachstumsmechanismen, Volumen/Intensität/Frequenz, Protein-Timing.
Periodisierung
Linear, undulierend, blockweise — strukturierte Trainingsplanung.
Schnellkraft
Power, Plyometrics, Olympic Lifts — Trainingsprinzipien.
Warm-up
RAMP-Protokoll, dynamisches Dehnen, neuronale Aktivierung.