IGF-1Studienlage & Dosis

Top-Studien zu IGF-1

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

1. 01

   Growth Hormone and IGF-1 Actions in the Brain and Neuropsychiatric Diseases

   Physiology·202680 einflussreiche Zitationen

   Growth hormone (GH) is secreted by the anterior pituitary gland under the control of hypothalamic neuroendocrine neurons that express somatostatin or growth hormone-releasing hormone (GHRH). Ghrelin, originating primarily in the stomach,…

2. 02

   IGF-1R Inhibitor IBI311 for the Treatment of Active Thyroid Eye Disease in Chinese Patients

   JAMA Ophthalmology·2025·n=5432 einflussreiche Zitationen

   <h4>Importance</h4>Thyroid eye disease (TED), a disfiguring and potentially sight-threatening condition with racial phenotypic variations, currently has limited effective treatments. Insulin-like growth factor 1 receptor (IGF-1R)…

3. 03

   Insulin-like growth factor I (IGF-I) and IGF binding protein-1 modulate prostate cancer cell growth and apoptosis: possible mediators for the effects of diet and exercise on cancer cell survival.

   Endocrinology·200325 einflussreiche Zitationen

   Previous studies showed that serum from men consuming a low fat diet and undergoing exercise intervention (DE) reduced LNCaP cell growth and induced apoptosis in vitro. DE also decreased serum IGF-I and increased serum IGF binding…

4. 04

   The regulation of insulin-like growth factor binding protein (IGFBP)-1 during prolonged fasting.

   Clinical endocrinology·199319 einflussreiche Zitationen

   <h4>Objective</h4>Insulin-like growth factor binding protein (IGFBP)-1 levels increase overnight, being inversely related to changes in insulin. With prolonged fasting IGFBP-1 levels increase further. In animal studies high IGFBP-1 levels…

5. 05

   Epigallocatechin gallate ameliorates oxaliplatin-induced peripheral neuropathy via upregulation of IGF-1 signaling and suppression of neuroinflammation

   Neuropharmacology·20253 einflussreiche Zitationen

   Chemotherapy-Induced Peripheral Neuropathy (CIPN) is a severe neurological complication characterized by persistent pain and sensory dysfunction. This study investigated the role of Insulin-like Growth Factor-1 (IGF-1) signaling in the…

6. 06

   IGF-1 regulates cancer cell immune evasion in prostate cancer

   Scientific Reports·20253 einflussreiche Zitationen

   Insulin-like growth factor-1 (IGF-1) is associated with prostate cancer (PCa) development and lethality and exhibits immunosuppressive properties in other models. We investigated IGF-1's tumor-intrinsic immune effects in PCa to understand…

7. 07

   Low-Intensity pulsed ultrasound enhances paracrine secretion of IGF and VEGF by bmscs, promoting osteogenesis and angiogenesis

   BMC Musculoskeletal Disorders·20253 einflussreiche Zitationen

   <h4>Background</h4>Low-intensity pulsed ultrasound (LIPUS) is an effective therapy for craniofacial bone regeneration. Paracrine signaling from mesenchymal stem cells (MSCs) plays a critical role in bone repair, but the impact of LIPUS on…

8. 08

   IGF-1R promotes pain-like behavior in rats with myofascial pain syndrome via the PI3K/AKT pathway

   Scientific Reports·20253 einflussreiche Zitationen

   Myofascial pain syndrome (MPS) is a common chronic pain condition characterized primarily by the presence of myofascial trigger points (MTrPs). While the insulin-like growth factor-1 receptor (IGF-1R) is known to be upregulated in injured…

9. 09

   Insulin-like Growth Factor 1 (IGF-1) in Hair Regeneration: Mechanistic Pathways and Therapeutic Potential

   Current Issues in Molecular Biology·20252 einflussreiche Zitationen

   IGF-1 (insulin-like growth factor 1) is a growth factor primarily secreted by dermal papilla cells on hair-bearing skin that stimulates hair follicle proliferation and vascularization, and promotes the transition to the anagen growth phase…

10. 10

    Modulatory Action of Insulin-like Growth Factor I (IGF-I) on Cortical Activity: Entrainment of Metabolic and Brain Functions

    Cells·20252 einflussreiche Zitationen

    Insulin-like growth factor I (IGF-I) is a neurotrophic factor that regulates neurogenesis, synaptogenesis, and neuronal survival. It also enhances neuronal activity and facilitates synaptic plasticity. Additionally, IGF-I plays a critical…