Kognition

PhosphatidylserineStudienlage & Dosis

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Studien zuletzt aktualisiert 18. Mai 2026

Studienlage in Zahlen

Studien gesamt: 620
Mit Abstract: 50
Meta / Systematic / RCT: 47
Häufig zitiert: 50
Erscheinungsjahre: 1983–2026

Phosphatidylserine im Kontext von Kognition

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Top-Studien zu Phosphatidylserine

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology.
Journal of lipid research2019D200 einflussreiche Zitationen
Exosomes are a type of extracellular vesicle released from cells after fusion of multivesicular bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM, glycosphingolipids, and phosphatidylserine. Lipids not…
Biomimetic exosome harnessing exosomal lipidomics and functional proteins for PEDF-pDNA delivery in high altitude pulmonary edema intervention.
Journal of controlled release : official journal of the Controlled Release Society2025E51 einflussreiche Zitationen
In the realm of gene therapy, given the exceptional performance of native exosomes, researchers have redirected their innovative focus towards exosome-mimetic nanovesicles (EMNs); however, the current design of most EMNs relies heavily on…
Phosphatidylserine and the human brain.
Nutrition (Burbank, Los Angeles County, Calif.)2015n=127D50 einflussreiche Zitationen
The aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted…
Phosphatidic acid plays key roles regulating plant development and stress responses.
Journal of integrative plant biology2018D49 einflussreiche Zitationen
Phospholipids, including phosphatidic acid (PA), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidylserine (PS) and phosphoinositides, have emerged as an important class of cellular messenger…
Annexin-V stabilizes membrane defects by inducing lipid phase transition.
Nature communications2020n=20E47 einflussreiche Zitationen
Annexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca2+-dependent manner. During cell injuries, the entry of extracellular Ca2+ activates the annexin membrane-binding…
Effects of phosphatidylserine in age-associated memory impairment.
Neurology1991n=149Clinical Trial43 einflussreiche Zitationen
We treated 149 patients meeting criteria for age-associated memory impairment (AAMI) for 12 weeks with a formulation of phosphatidylserine (100 mg BC-PS tid) or placebo. Patients treated with the drug improved relative to those treated…
Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke.
Stroke2025E43 einflussreiche Zitationen
Activating glutamatergic neurons in the ipsilesional motor cortex can promote functional recovery after stroke. However, the underlying molecular mechanisms remain unclear. Clarifying key molecular mechanisms involved in recovery could…
Phosphatidylserine-incorporated exosome mimetics encapsulating CXCR3 antagonist alleviate osteoporosis.
Advanced functional materials2024E40 einflussreiche Zitationen
Exosomes derived from mesenchymal stem cells are an active area of research due to their therapeutic potential in treating osteoporosis. To further harness their therapeutic performance in modulating bone resorption, we have equipped…
Nicotinamide loaded functionalized solid lipid nanoparticles improves cognition in Alzheimer's disease animal model by reducing Tau hyperphosphorylation.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2018E39 einflussreiche Zitationen
Nicotinamide is considered to be effective in halting the Alzheimer's disease progression. The body could absorb a limited amount of nicotinamide at a time, requiring multiple doses through a day. To overcome such an obstacle which reduces…
Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study.
Oncotarget2017n=44RCT33 einflussreiche Zitationen
There are no suitable screening modalities for ovarian carcinomas (OC) and repeated imaging and CA-125 levels are often needed to triage equivocal ovarian masses. Definitive diagnosis of malignancy, however, can only be established by…

Häufige Fragen

Welche Dosierung wurde in den Studien untersucht?

• Exogenous phosphatidylserine (PS) (300-800 mg/d)

Gibt es Sicherheitshinweise zu Phosphatidylserine?

• Exogenous PS was reported as safely absorbed in humans. • Dose range mentioned was 300-800 mg/d. • No adverse events were described in the abstract. • Minimally invasive blood draw only; no treatment exposure.