PhosphatidylserineEvidence & Dosage
Cortisol reduction, memory and dementia studies.
Evidence at a glance
- Total studies
- 620
- With abstract
- 50
- Meta / Systematic / RCT
- 47
- Highly cited
- 50
- Publication years
- 1983–2026
Phosphatidylserine in the context of Cognition
This topic is part of our "Cognition" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to CognitionTop studies on Phosphatidylserine
Ranked by influential-citation count and publication year.
Exosomal lipid composition and the role of ether lipids and phosphoinositides in exosome biology.
Journal of lipid research2019D200 influential citationsExosomes are a type of extracellular vesicle released from cells after fusion of multivesicular bodies with the plasma membrane. These vesicles are often enriched in cholesterol, SM, glycosphingolipids, and phosphatidylserine. Lipids not…
Biomimetic exosome harnessing exosomal lipidomics and functional proteins for PEDF-pDNA delivery in high altitude pulmonary edema intervention.
Journal of controlled release : official journal of the Controlled Release Society2025E51 influential citationsIn the realm of gene therapy, given the exceptional performance of native exosomes, researchers have redirected their innovative focus towards exosome-mimetic nanovesicles (EMNs); however, the current design of most EMNs relies heavily on…
Phosphatidylserine and the human brain.
Nutrition (Burbank, Los Angeles County, Calif.)2015n=127D50 influential citationsThe aim of this study was to assess the roles and importance of phosphatidylserine (PS), an endogenous phospholipid and dietary nutrient, in human brain biochemistry, physiology, and function. A scientific literature search was conducted…
Phosphatidic acid plays key roles regulating plant development and stress responses.
Journal of integrative plant biology2018D49 influential citationsPhospholipids, including phosphatidic acid (PA), phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidylglycerol (PG), phosphatidylserine (PS) and phosphoinositides, have emerged as an important class of cellular messenger…
Annexin-V stabilizes membrane defects by inducing lipid phase transition.
Nature communications2020n=20E47 influential citationsAnnexins are abundant cytoplasmic proteins, which bind to membranes that expose negatively charged phospholipids in a Ca2+-dependent manner. During cell injuries, the entry of extracellular Ca2+ activates the annexin membrane-binding…
Effects of phosphatidylserine in age-associated memory impairment.
Neurology1991n=149Clinical Trial43 influential citationsWe treated 149 patients meeting criteria for age-associated memory impairment (AAMI) for 12 weeks with a formulation of phosphatidylserine (100 mg BC-PS tid) or placebo. Patients treated with the drug improved relative to those treated…
Enhancing Neuron Activity Promotes Functional Recovery by Inhibiting Microglia-Mediated Synapse Elimination After Stroke.
Stroke2025E43 influential citationsActivating glutamatergic neurons in the ipsilesional motor cortex can promote functional recovery after stroke. However, the underlying molecular mechanisms remain unclear. Clarifying key molecular mechanisms involved in recovery could…
Phosphatidylserine-incorporated exosome mimetics encapsulating CXCR3 antagonist alleviate osteoporosis.
Advanced functional materials2024E40 influential citationsExosomes derived from mesenchymal stem cells are an active area of research due to their therapeutic potential in treating osteoporosis. To further harness their therapeutic performance in modulating bone resorption, we have equipped…
Nicotinamide loaded functionalized solid lipid nanoparticles improves cognition in Alzheimer's disease animal model by reducing Tau hyperphosphorylation.
Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences2018E39 influential citationsNicotinamide is considered to be effective in halting the Alzheimer's disease progression. The body could absorb a limited amount of nicotinamide at a time, requiring multiple doses through a day. To overcome such an obstacle which reduces…
Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study.
Oncotarget2017n=44RCT33 influential citationsThere are no suitable screening modalities for ovarian carcinomas (OC) and repeated imaging and CA-125 levels are often needed to triage equivocal ovarian masses. Definitive diagnosis of malignancy, however, can only be established by…
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