Lipid ProfileEvidence & Dosage

Top studies on Lipid Profile

Ranked by influential-citation count (Semantic Scholar) and publication year.

1. 01

   Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events.

   The New England journal of medicine·2002200 influential citations

   <h4>Background</h4>Both C-reactive protein and low-density lipoprotein (LDL) cholesterol levels are elevated in persons at risk for cardiovascular events. However, population-based data directly comparing these two biologic markers are not…

2. 02

   Dietary lipid predictors of coronary heart disease in men. The Framingham Study.

   Archives of internal medicine·1991·n=42036 influential citations

   The relationship between dietary lipids and the 16-year incidence of coronary heart disease (CHD) morbidity and mortality was examined in two male cohorts, aged 45 to 55 years (n = 420) and 56 to 65 years (n = 393) from the Framingham…

3. 03

   Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease

   New England Journal of Medicine·2026·n=3,0481 influential citations

   <h4>Background</h4>Despite guideline recommendations, evidence from randomized trials evaluating the appropriate low-density lipoprotein (LDL) cholesterol target for secondary prevention in patients with atherosclerotic cardiovascular…

4. 04

   Polygenic risk scores enhance LDL cholesterol–based risk stratification for coronary artery disease

   American Journal of Preventive Cardiology·20261 influential citations

   <h4>Background</h4>Genetic risk for coronary artery disease (CAD) can be estimated using polygenic risk scores (PRS), but greater clarity is needed on how PRS might inform clinical risk assessment and prevention. We assessed the risk for…

5. 05

   <scp>IL</scp> ‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised <scp>LDL</scp> and Complement Pathways

   Allergy·2026

   Background IL‐33 levels are elevated in the airways of patients with eosinophilic diseases, and IL‐33 receptor expression on eosinophils is upregulated in type 2‐high environments. However, the role of IL‐33 in the regulation of human…

6. 06

   Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway

   Stem Cell Research &amp; Therapy·2026

   Neuroinflammation is a key pathogenic factor for neurodegenerative diseases. Mesenchymal stem cell (MSC) transplantation, as a potential strategy for regulating neuroinflammation, has received extensive attention. Our previous research…

7. 07

   Attaining LDL-cholesterol target post major coronary event: Care gap, associated factors and clinical outcomes

   American Heart Journal·2026·n=47,416

   <h4>Background</h4>Despite evidence supporting low-density lipoprotein cholesterol (LDL-C) reduction below 70 mg/dL after a major acute coronary event (MACE), many patients fail to reach this target.<h4>Methods</h4>Retrospective cohort…

8. 08

   High LDL-cholesterol in children and adolescents with type 1 diabetes: the impact of body adiposity and sex

   Nutrition, Metabolism and Cardiovascular Diseases·2026

   <h4>Background and aims</h4>To investigate the association between LDL cholesterol (LDL-C) and body adiposity in children and adolescents with type 1 diabetes (T1D), evaluating the influence of sex, glycemic control, and insulin treatment…

9. 09

   Transcriptomic identification of PDK4 as a potential target of leonurine to ox-LDL-induced inflammation and lipid accumulation in THP-1 macrophages

   Biochemical and Biophysical Research Communications·2026

   <h4>Background</h4>Although leonurine (LEO) has been extensively studied for the significant anti-atherosclerotic (AS) activity, its underlying molecular targets remain incompletely to be elucidated. This study aimed to explore the key…

10. 10

    Development of a chemometric-assisted SERS method for simultaneous analysis of HDL and LDL cholesterol in blood serum with silver nanoparticles as substrate.

    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy·2026

    Cardiovascular diseases (CVD) are becoming a serious threat to human health. These are considered the leading causes of mortality. Abnormal lipid concentrations in the body, such as High-density lipoproteins (HDL) and Low-density…

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