Lipid ProfileEvidence & Dosage
LDL-C, HDL, triglycerides, ApoB — modern cardiovascular risk assessment.
Evidence at a glance
- Total studies
- 629
- With abstract
- 34
- Meta / Systematic / RCT
- 1
- Highly cited
- 2
- Publication years
- 1977–2026
Lipid Profile in the context of Diagnostics & Biomarkers
This topic is part of our "Diagnostics & Biomarkers" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to Diagnostics & BiomarkersTop studies on Lipid Profile
Ranked by influential-citation count and publication year.
Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events.
The New England journal of medicine2002200 influential citations<h4>Background</h4>Both C-reactive protein and low-density lipoprotein (LDL) cholesterol levels are elevated in persons at risk for cardiovascular events. However, population-based data directly comparing these two biologic markers are not…
Dietary lipid predictors of coronary heart disease in men. The Framingham Study.
Archives of internal medicine1991n=42036 influential citationsThe relationship between dietary lipids and the 16-year incidence of coronary heart disease (CHD) morbidity and mortality was examined in two male cohorts, aged 45 to 55 years (n = 420) and 56 to 65 years (n = 393) from the Framingham…
Intensive LDL Cholesterol Targeting in Atherosclerotic Cardiovascular Disease
New England Journal of Medicine2026n=3,0481 influential citations<h4>Background</h4>Despite guideline recommendations, evidence from randomized trials evaluating the appropriate low-density lipoprotein (LDL) cholesterol target for secondary prevention in patients with atherosclerotic cardiovascular…
Polygenic risk scores enhance LDL cholesterol–based risk stratification for coronary artery disease
American Journal of Preventive Cardiology20261 influential citations<h4>Background</h4>Genetic risk for coronary artery disease (CAD) can be estimated using polygenic risk scores (PRS), but greater clarity is needed on how PRS might inform clinical risk assessment and prevention. We assessed the risk for…
<scp>IL</scp> ‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised <scp>LDL</scp> and Complement Pathways
Allergy2026Background IL‐33 levels are elevated in the airways of patients with eosinophilic diseases, and IL‐33 receptor expression on eosinophils is upregulated in type 2‐high environments. However, the role of IL‐33 in the regulation of human…
Tanshinone IIA-pretreated mesenchymal stem cells alleviate neuroinflammation in 3×Tg-AD mice via the TREM2/PI3K/Akt pathway
Stem Cell Research & Therapy2026Neuroinflammation is a key pathogenic factor for neurodegenerative diseases. Mesenchymal stem cell (MSC) transplantation, as a potential strategy for regulating neuroinflammation, has received extensive attention. Our previous research…
Attaining LDL-cholesterol target post major coronary event: Care gap, associated factors and clinical outcomes
American Heart Journal2026n=47,416<h4>Background</h4>Despite evidence supporting low-density lipoprotein cholesterol (LDL-C) reduction below 70 mg/dL after a major acute coronary event (MACE), many patients fail to reach this target.<h4>Methods</h4>Retrospective cohort…
High LDL-cholesterol in children and adolescents with type 1 diabetes: the impact of body adiposity and sex
Nutrition, Metabolism and Cardiovascular Diseases2026<h4>Background and aims</h4>To investigate the association between LDL cholesterol (LDL-C) and body adiposity in children and adolescents with type 1 diabetes (T1D), evaluating the influence of sex, glycemic control, and insulin treatment…
Transcriptomic identification of PDK4 as a potential target of leonurine to ox-LDL-induced inflammation and lipid accumulation in THP-1 macrophages
Biochemical and Biophysical Research Communications2026<h4>Background</h4>Although leonurine (LEO) has been extensively studied for the significant anti-atherosclerotic (AS) activity, its underlying molecular targets remain incompletely to be elucidated. This study aimed to explore the key…
Development of a chemometric-assisted SERS method for simultaneous analysis of HDL and LDL cholesterol in blood serum with silver nanoparticles as substrate.
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy2026Cardiovascular diseases (CVD) are becoming a serious threat to human health. These are considered the leading causes of mortality. Abnormal lipid concentrations in the body, such as High-density lipoproteins (HDL) and Low-density…
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