Liver ValuesEvidence & Dosage

Top studies on Liver Values

Ranked by influential-citation count and publication year.

1. 01

   Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions.

   The American journal of gastroenterology·1999·n=51200 influential citations

   <h4>Objective</h4>Steatohepatitis is a morphological pattern of liver injury that may be seen in alcoholic or nonalcoholic liver disease. This pattern may occur with obesity, diabetes, the use of certain drugs, or the cause may be…

2. 02

   Transient elastography: a new noninvasive method for assessment of hepatic fibrosis.

   Ultrasound in medicine &amp; biology·2003·n=106200 influential citations

   Chronic hepatitis is accompanied by progressive deposit of hepatic fibrosis, which may lead to cirrhosis. Evaluation of liver fibrosis is, thus, of great clinical interest and, up to now, has been assessed with liver biopsy. This work aims…

3. 03

   Nonalcoholic fatty liver disease: a feature of the metabolic syndrome.

   Diabetes·2001·n=30200 influential citations

   Insulin sensitivity (euglycemic clamp, insulin infusion rate: 40 mU. m(-2). min(-1)) was studied in 30 subjects with biopsy-proven nonalcoholic fatty liver disease (NAFLD), normal glucose tolerance, and a BMI <30 kg/m(2). Of those 30…

4. 04

   Long-term follow-up of patients with NAFLD and elevated liver enzymes.

   Hepatology (Baltimore, Md.)·2006·n=88200 influential citations

   Nonalcoholic fatty liver disease (NAFLD) is the most common cause of elevated liver enzymes in patients of developed countries. We determined the long-term clinical and histological courses of such patients. In a cohort study, 129…

5. 05

   FIB-4: an inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest.

   Hepatology (Baltimore, Md.)·2007200 influential citations

   <h4>Unlabelled</h4>To optimize the management of patients with chronic hepatitis C virus (HCV) infection, noninvasive tests to determine the degree of hepatic fibrosis have been developed. The aims of this study were (1) to validate a…

6. 06

   Sampling variability of liver biopsy in nonalcoholic fatty liver disease.

   Gastroenterology·2005·n=17200 influential citations

   <h4>Background & aims</h4>In nonalcoholic fatty liver disease (NAFLD), the distinction between steatosis and steatohepatitis (NASH) and the assessment of the severity of the disease rely on liver histology alone. The aim of this study was…

7. 07

   Comparison of noninvasive markers of fibrosis in patients with nonalcoholic fatty liver disease.

   Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2009·n=541200 influential citations

   <h4>Background & aims</h4>There is a need for a reliable and inexpensive noninvasive marker of hepatic fibrosis in patients with nonalcoholic fatty liver disease (NAFLD). We compared the performance of the FIB4 index (based on age,…

8. 08

   Performance of transient elastography for the staging of liver fibrosis: a meta-analysis.

   Gastroenterology·2008200 influential citations

   <h4>Background & aims</h4>Transient elastography has been studied in a multitude of liver diseases for the staging of liver fibrosis with variable results. A meta-analysis was performed to assess the overall performance of transient…

9. 09

   Prevalence of fatty liver in children and adolescents.

   Pediatrics·2006·n=742200 influential citations

   <h4>Objective</h4>Fatty liver disease is diagnosed increasingly in children, but the prevalence remains unknown. We sought to determine the prevalence of pediatric fatty liver as diagnosed by histology in a population-based…

10. 10

    Non-invasive evaluation of liver fibrosis using transient elastography.

    Journal of hepatology·2008200 influential citations

    Transient elastography (TE, FibroScan) is a novel non-invasive method that has been proposed for the assessment of hepatic fibrosis in patients with chronic liver diseases, by measuring liver stiffness. TE is a rapid and user-friendly…