CravingsEvidence & Dosage

Top studies on Cravings

Ranked by influential-citation count and publication year.

1. 01

   Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.

   The Journal of neuroscience : the official journal of the Society for Neuroscience·2006200 influential citations

   The ability of drugs of abuse to increase dopamine in nucleus accumbens underlies their reinforcing effects. However, preclinical studies have shown that with repeated drug exposure neutral stimuli paired with the drug (conditioned…

2. 02

   Psychometric properties of the Penn Alcohol Craving Scale.

   Alcoholism, clinical and experimental research·1999·n=147197 influential citations

   <h4>Background</h4>This study introduces the Penn Alcohol Craving Scale (PACS), which has been used in several clinical trials at the University of Pennsylvania's Treatment Research Center. The PACS is a five-item, self-report measure that…

3. 03

   Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving.

   Nature·2008176 influential citations

   Relapse to cocaine use after prolonged abstinence is an important clinical problem. This relapse is often induced by exposure to cues associated with cocaine use. To account for the persistent propensity for relapse, it has been suggested…

4. 04

   Drug craving and addiction: integrating psychological and neuropsychopharmacological approaches.

   Progress in neuro-psychopharmacology &amp; biological psychiatry·2003160 influential citations

   In the present review, an integrated approach to craving and addiction is discussed, which is based on recent insights from psychology and neuropsychopharmacology. An integrated model explains craving and relapse in humans by the…

5. 05

   The development of a cocaine craving questionnaire.

   Drug and alcohol dependence·1993109 influential citations

   Two versions of a 45-item questionnaire on cocaine craving were administered to 225 cocaine users. The Now version asked about current craving for cocaine, and the General version asked about average craving over the preceding week. Factor…

6. 06

   Development and validation of the food-craving inventory.

   Obesity research·2002·n=474101 influential citations

   <h4>Objective</h4>The primary aim of this study was to develop and validate the Food-Craving Inventory (FCI), a self-report measure of specific food cravings.<h4>Research methods and procedures</h4>In a preliminary study, participants (n =…

7. 07

   Depression, craving, and substance use following a randomized trial of mindfulness-based relapse prevention.

   Journal of consulting and clinical psychology·2010·n=16895 influential citations

   <h4>Objective</h4>A strong relation between negative affect and craving has been demonstrated in laboratory and clinical studies, with depressive symptomatology showing particularly strong links to craving and substance abuse relapse.…

8. 08

   Hypothalamic-pituitary-adrenal axis and sympatho-adreno-medullary responses during stress-induced and drug cue-induced cocaine craving states.

   Psychopharmacology·200377 influential citations

   <h4>Rationale</h4>Environmental stimuli associated with cocaine are known to elicit drug craving and increase the likelihood of relapse. However, the psychobiological changes that occur with exposure to these stimuli and in episodes of…

9. 09

   Effects of Omega-3 Fatty Acids on Tobacco Craving in Tobacco Users: A Single-blind, Randomized, Placebo-controlled Study.

   ·2026

   <h4>Background</h4>Tobacco use and its smoke produces oxidative stress in the body, which eventually triggers cell damage by lipid peroxidation. Smokers report lower levels of omega-3 fatty acids (FAs) in their serum as compared to…

10. 10

    When trauma triggers craving: meta-analytic evidence for the mediating role of negative affect among trauma-exposed individuals who use substances.

    European journal of psychotraumatology·2026·n=32

    <b>Background:</b> In experimental studies using the cue reactivity paradigm (CRP), classically conditioned substance craving is well-documented among individuals who use substances with trauma histories. However, the magnitude of this…