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EndometriosisEvidence & Dosage

A chronic inflammatory disease — diagnosis, options, lifestyle factors.

Evidence at a glance

Total studies
864
With abstract
43
Meta / Systematic / RCT
1
Highly cited
7
Publication years
1980–2026

Endometriosis in the context of Hormones

This topic is part of our "Hormones" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

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Top studies on Endometriosis

Ranked by influential-citation count and publication year.

  1. Epidemiology of endometriosis.

    Obstetrics and gynecology clinics of North America1997200 influential citations

    This article summarizes present knowledge about the epidemiology of endometriosis. Surprisingly, little is known about the prevalence or risk factors of endometriosis, given the medical care and employment costs. Knowledge about the…

  2. Prevalence of endometriosis in asymptomatic women.

    The Journal of reproductive medicine1991n=8665 influential citations

    Numerous studies have identified the presence of endometriosis by its "classic" morphologic characteristics in high-risk patient populations. Recent histologic documentation of "subtle" laparoscopic appearances of this condition suggests…

  3. Angiogenic factors in endometriosis.

    Annals of the New York Academy of Sciences200264 influential citations

    Similar to tumor metastases, endometriotic implants require neovascularization to establish, grow, and invade. The peritoneal environment is ideally suited to provide a proangiogenic milieu. Nevertheless, endometriotic lesions are found…

  4. Is Endometriosis Staging Related to the Type and Intensity of Patients’ Complaints? A Systematic Review and Meta-Analysis

    Journal of Minimally Invasive Gynecology202650 influential citations

    <h4>Objective</h4>To evaluate the association between the endometriosis staging and the type and intensity of pain reported by patients, describing the pain intensity across different pain types.<h4>Data sources</h4>On January 27, 2025, a…

  5. Treatment of endometriosis and chronic pelvic pain with letrozole and norethindrone acetate: a pilot study.

    Fertility and sterility2004n=1048 influential citations

    <h4>Objective</h4>To determine the role of an aromatase inhibitor, letrozole, in the treatment of reproductive-age women with endometriosis and associated chronic pelvic pain.<h4>Design</h4>Phase 2, open-label, nonrandomized…

  6. Pathogenesis of endometriosis.

    Obstetrics and gynecology clinics of North America200332 influential citations

    Endometriosis is a common gynecologic disorder characterized by the presence of endometrial tissue outside the uterine cavity. Various theories have been put forth to explain the mechanisms for the development of this disease. Although no…

  7. Intraoperative enhanced imaging for detection of endometriosis: A systematic review of the literature.

    Eur J Obstet Gynecol Reprod Biol2018n=171Systematic Review13 influential citations

    The diagnosis of peritoneal endometriosis during laparoscopy may be difficult due to the polymorphic aspects of the lesions. Enhanced imaging using contrast agents has potential to provide a better identification of peritoneal…

  8. Endometriosis and comorbidities: molecular mechanisms and clinical implications

    Trends in Molecular Medicine20264 influential citations

    Endometriosis, traditionally viewed as a gynecological condition, is increasingly recognized as a systemic disease due to its frequent association with inflammatory and autoimmune comorbidities. Recent molecular and genetic insights reveal…

  9. Ultrasound as a noninvasive diagnostic tool to detect deep endometriosis using the International Deep Endometriosis Analysis terminology

    Fertility and Sterility20262 influential citations

    <h4>Objective</h4>To evaluate the performance of transvaginal ultrasound (TVS) using the International Deep Endometriosis Analysis (IDEA) terminology in the detection of deep endometriosis (DE).<h4>Design</h4>International multicenter…

  10. Presence And Laterality Of Endometriosis In Adolescent Patients With Obstructed Müllerian Duct Anomalies, A Twenty-Three Year Retrospective Cohort Analysis Between 2002 – 2025 At An Australian Quaternary Paediatric And Adolescent Gynaecology Service

    Journal of Pediatric and Adolescent Gynecology20261 influential citations

    <h4>Study objective</h4>To determine the prevalence and laterality of endometriosis in adolescents with obstructed Müllerian duct anomalies (MDAs).<h4>Methods</h4>A retrospective cohort study of 42 adolescents with surgically confirmed…

Frequently asked

Are there safety considerations for Endometriosis?
• Seven complications were reported overall. • All reported complications were related to 5-ALA.

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