Kognition

DopaminStudienlage & Dosis

Motivation, Belohnung, Bewegung, Lernen — zentrale Reward-Chemie.

Studienlage in Zahlen

Studien gesamt: 1.000
Mit Abstract: 43
Meta / Systematic / RCT: 0
Häufig zitiert: 20
Erscheinungsjahre: 1958–2026

Dopamin im Kontext von Kognition

Dieses Thema ist Teil unserer Welt „Kognition". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Kognition

Top-Studien zu Dopamin

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

The neural basis of human error processing: reinforcement learning, dopamine, and the error-related negativity.
Psychological review2002200 einflussreiche Zitationen
The authors present a unified account of 2 neural systems concerned with the development and expression of adaptive behaviors: a mesencephalic dopamine system for reinforcement learning and a "generic" error-processing system associated…
D1 and D2 dopamine receptor-regulated gene expression of striatonigral and striatopallidal neurons.
Science (New York, N.Y.)1990200 einflussreiche Zitationen
The striatum, which is the major component of the basal ganglia in the brain, is regulated in part by dopaminergic input from the substantia nigra. Severe movement disorders result from the loss of striatal dopamine in patients with…
Transplantation of embryonic dopamine neurons for severe Parkinson's disease.
The New England journal of medicine2001n=40200 einflussreiche Zitationen
<h4>Background</h4>Transplantation of human embryonic dopamine neurons into the brains of patients with Parkinson's disease has proved beneficial in open clinical trials. However, whether this intervention would be more effective than sham…
Essential role of BDNF in the mesolimbic dopamine pathway in social defeat stress.
Science (New York, N.Y.)2006200 einflussreiche Zitationen
Mice experiencing repeated aggression develop a long-lasting aversion to social contact, which can be normalized by chronic, but not acute, administration of antidepressant. Using viral-mediated, mesolimbic dopamine pathway-specific…
Brain dopamine and obesity.
Lancet (London, England)2001200 einflussreiche Zitationen
<h4>Background</h4>The cerebral mechanisms underlying the behaviours that lead to pathological overeating and obesity are poorly understood. Dopamine, a neurotransmitter that modulates rewarding properties of food, is likely to be…
Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats.
Nature neuroscience2010n=11200 einflussreiche Zitationen
We found that development of obesity was coupled with emergence of a progressively worsening deficit in neural reward responses. Similar changes in reward homeostasis induced by cocaine or heroin are considered to be crucial in triggering…
Whole-brain mapping of direct inputs to midbrain dopamine neurons.
Neuron2012200 einflussreiche Zitationen
Recent studies indicate that dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) convey distinct signals. To explore this difference, we comprehensively identified each area's monosynaptic inputs…
Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit/hyperactivity disorder.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2002200 einflussreiche Zitationen
The selective norepinephrine (NE) transporter inhibitor atomoxetine (formerly called tomoxetine or LY139603) has been shown to alleviate symptoms in Attention Deficit/Hyperactivity Disorder (ADHD). We investigated the mechanism of action…
Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction.
The Journal of neuroscience : the official journal of the Society for Neuroscience2006200 einflussreiche Zitationen
The ability of drugs of abuse to increase dopamine in nucleus accumbens underlies their reinforcing effects. However, preclinical studies have shown that with repeated drug exposure neutral stimuli paired with the drug (conditioned…
Inverted-U dopamine D1 receptor actions on prefrontal neurons engaged in working memory.
Nature neuroscience2007200 einflussreiche Zitationen
Dopamine (DA) D1 receptor (D1R) stimulation in prefrontal cortex (PFC) produces an 'inverted-U' dose-response, whereby either too little or too much D1R stimulation impairs spatial working memory. This response has been observed across…