Hormone

DHTStudienlage & Dosis

Aktivster Androgen-Metabolit — Haarausfall, Prostata, Libido.

Studienlage in Zahlen

Studien gesamt: 926
Mit Abstract: 48
Meta / Systematic / RCT: 0
Häufig zitiert: 12
Erscheinungsjahre: 1953–2026

DHT im Kontext von Hormone

Dieses Thema ist Teil unserer Welt „Hormone". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

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Top-Studien zu DHT

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Marked decline in serum concentrations of adrenal C19 sex steroid precursors and conjugated androgen metabolites during aging.
The Journal of clinical endocrinology and metabolism1997177 einflussreiche Zitationen
The present data show a dramatic decline in the circulating levels of dehydroepiandrosterone (DHEA), DHEA-sulfate (DHEA-S), androst-5-ene-3 beta,17 beta-diol (5-diol), 5-diol-sulfate, 5-diol-fatty acid esters, and androstenedione in both…
Finasteride in the treatment of men with androgenetic alopecia. Finasteride Male Pattern Hair Loss Study Group.
Journal of the American Academy of Dermatology1998n=155165 einflussreiche Zitationen
<h4>Background</h4>Androgenetic alopecia (male pattern hair loss) is caused by androgen-dependent miniaturization of scalp hair follicles, with scalp dihydrotestosterone (DHT) implicated as a contributing cause. Finasteride, an inhibitor…
Human 3alpha-hydroxysteroid dehydrogenase isoforms (AKR1C1-AKR1C4) of the aldo-keto reductase superfamily: functional plasticity and tissue distribution reveals roles in the inactivation and formation of male and female sex hormones.
The Biochemical journal2000131 einflussreiche Zitationen
The kinetic parameters, steroid substrate specificity and identities of reaction products were determined for four homogeneous recombinant human 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) isoforms of the aldo-keto reductase (AKR)…
A new rat model exhibiting both ovarian and metabolic characteristics of polycystic ovary syndrome.
Endocrinology2007111 einflussreiche Zitationen
Polycystic ovary syndrome (PCOS) is a complex endocrine and metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, abdominal obesity, and insulin resistance. However, its etiology is unclear, and its management is…
Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway.
Endocrinology2003110 einflussreiche Zitationen
Testosterone supplementation increases skeletal muscle mass and decreases fat mass; however, the underlying mechanisms are unknown. We hypothesized that testosterone regulates body composition by promoting the commitment of mesenchymal…
Physiological changes in dehydroepiandrosterone are not reflected by serum levels of active androgens and estrogens but of their metabolites: intracrinology.
The Journal of clinical endocrinology and metabolism199787 einflussreiche Zitationen
This study analyzes in detail the serum concentration of the active androgens and estrogens, as well as a series of free and conjugated forms of their precursors and metabolites, after daily application for 2 weeks of 10 mL 20%…
The role of dihydrotestosterone in benign prostatic hyperplasia.
Urology200383 einflussreiche Zitationen
This article examines the role of the androgen dihydrotestosterone (DHT) in the healthy and diseased prostate and considers the implications of the data on DHT for therapeutic approaches to benign prostatic hyperplasia (BPH). Development…
Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer.
Proceedings of the National Academy of Sciences of the United States of America201182 einflussreiche Zitationen
In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapy by depletion of gonadal testosterone. The response is usually transient, and metastatic tumors almost invariably eventually progress as…
A double-blind, placebo-controlled, randomized clinical trial of transdermal dihydrotestosterone gel on muscular strength, mobility, and quality of life in older men with partial androgen deficiency.
The Journal of clinical endocrinology and metabolism2001n=1956 einflussreiche Zitationen
The efficacy and safety of androgen supplementation in older men remains controversial. Despite biochemical evidence of partial androgen deficiency in older men, controlled studies using T demonstrate equivocal benefits. Furthermore, the…
Testosterone and DHEA activate the glucose metabolism-related signaling pathway in skeletal muscle.
American journal of physiology. Endocrinology and metabolism200842 einflussreiche Zitationen
Circulating dehydroepiandrosterone (DHEA) is converted to testosterone or estrogen in the target tissues. Recently, we demonstrated that skeletal muscles are capable of locally synthesizing circulating DHEA to testosterone and estrogen.…