StammzellenStudienlage & Dosis
Klinische Anwendungen, Hype, Off-Label-Risiken im Ausland.
Studienlage in Zahlen
- Studien gesamt
- 342
- Mit Abstract
- 46
- Meta / Systematic / RCT
- 0
- Häufig zitiert
- 1
- Erscheinungsjahre
- 1999–2026
Stammzellen im Kontext von Longevity
Dieses Thema ist Teil unserer Welt „Longevity". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.
Zur Welt LongevityTop-Studien zu Stammzellen
Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.
Cancer stem cells and their vascular niche: Do they benefit from each other?
Cancer Lett2016Review9 einflussreiche ZitationenCancer stem cells (CSCs) locate in and interact with particular vascular niches to maintain their stemness. CSCs induce, remodel and participate in the formation of microenvironmental niches to facilitate survival, stemness and escape from…
Immune cells adapt to distinct stem cell niches to govern tissue homeostasis
bioRxiv20261 einflussreiche ZitationenSummary Paragraph In adult tissues, epithelial stem cells exist within distinct residences, each endowing them with exclusive instructions for regenerative fitness under homeostasis and stress. Key components of these ‘niches’ are immune…
Immunotherapy and postoperative bone defect repair strategies based on osteosarcoma tumor microenvironment characteristics: balancing antitumor effects and promotion of bone regeneration.
Regenerative biomaterials2026Advances in orthopedic biomaterials have significantly improved the bone regeneration domain; however, postoperative bone defect repair after bone tumor resection—particularly for osteosarcoma, a common primary malignant bone tumor in…
NOTCH3 signal activation by its extracellular domain accumulation in an iPSC line newly established from a CADASIL patient.
Human cell2026ECerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most common monogenic cerebral small-vessel disease caused by NOTCH3 mutations, yet its pathogenic mechanisms remain incompletely…
The progress of mitochondrial function and transfer in stem cell regulation and therapy.
Journal of physiology and biochemistry2026n=6DMitochondria, serving as central organelles for energy metabolism, play a critical regulatory role in stem cell self-renewal and differentiation-a function increasingly supported by accumulating evidence and closely linked to various…
Photobiomodulation-induced Differentiation of Adipose-derived Stem Cells into Neuronal Organoid-like Structures.
Molecular neurobiology2026EThe ability to regulate stem cell differentiation into organized neural tissue remains a major challenge in regenerative medicine, particularly in the development of physiologically relevant three-dimensional (3D) organoid models.…
Aspirin-induced mesenchymal stem cell-derived extracellular vesicles promote osteochondral regeneration by reprogramming macrophages
Biomaterials2026Persistent inflammatory responses in osteochondral defects produce a hostile microenvironment that severely compromises endogenous tissue repair mechanisms. The local immune microenvironment needs to be modulated to facilitate tissue…
Artificial human stem cell niche created in cartilage-inspired hydrogel for enhanced articular cartilage regeneration
Biomaterials2026Stem cell-based therapies and liposome-integrated hydrogel matrix strategies are promising for articular cartilage regeneration. However, challenges persist due to the loss of stemness during in vitro expansion and the lack of control over…
Human adipose stem cell conditioned medium has a pro-fibrotic and EMT-stimulating effect on urethral fibroblasts in vitro
European Journal of Cell Biology2026Fibrosis, characterized by excessive deposition of scar tissue, leads to the dysfunction of various organs. An urethral stricture, or pathological narrowing of the urethra, is an example of such scarring. The use of human adipose stem cell…
Dynamic PEGDA-GelMA-HAMA microcarriers for efficient ex vivo expansion of human hematopoietic stem/progenitor cells
Colloids and Surfaces B: Biointerfaces2026The clinical demand for hematopoietic stem cells (HSCs) far exceeds that of the available sources, driving the need for efficient ex vivo expansion technologies. A central challenge is the design of culture systems that promote HSCs…
Häufige Fragen
Für welche Population gilt die Evidenz?
Weitere Themen in Longevity
Zone 2
Niedrig-intensives Cardio — mitochondriale Biogenese, Longevity-Basis.
Rapamycin
mTOR-Inhibition, Langlebigkeits-Studien, Off-Label-Dosierung und Sicherheit.
AMPK Activators
Berberin, Alpha-Liponsäure, energetic stress und Glukose-Modulation.
ApoB
Bessere kardiovaskuläre Risiko-Metrik als LDL-C — moderne Lipidologie.
Autophagie
Zellulärer Selbstabbau — Fasten, Sport, Spermidin als Trigger.
Berberin
Glukose, Lipide, AMPK und GI-Verträglichkeits-Daten.
Biologisches Alter
GrimAge, PhenoAge, DunedinPACE — was Epigenetik-Uhren messen.
Caloric Restriction
CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.
Krebsfrüherkennung
Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).
Zelluläre Seneszenz
„Zombie-Zellen", SASP, Senolytika-Ansätze.
Kollagen
Haut, Gelenke, Sehnen — Evidenz pro Hydrolysat plus Vitamin C.
Demenz-Prävention
Lifestyle-Faktoren: Bewegung, Schlaf, Hörgesundheit, Vaskuläre Gesundheit.
DEXA-Knochendichte
DEXA-Scan für Knochen + Körperzusammensetzung — Verlauf wichtiger als Einzelwert.
Epigenetische Uhren
Horvath, GrimAge, PhenoAge — was sie messen und nicht messen.
Epigenetik
DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.
Exosomen
Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.
Genetiktests
Variants, Pharmacogenomik, Limitationen — Methylierung, MTHFR-Mythen.
Glucosamine
Gelenke, UK Biobank Mortalitäts-Studie, Sulfat vs HCl-Formen.
Glycin
Methylierung, Kollagensynthese, Lebensspannen-Hinweise in Tiermodellen.
Griffkraft
Starker Mortalitäts-Prädiktor — einfach messbar, trainierbar.
Verwandte Themen aus anderen Welten
Co-Regulation
Nervensystem-Regulation in Beziehung — Bindung, Therapie, Eltern-Kind.
Fight/Flight/Freeze
Stress-Antwort-Muster, somatische Manifestation, Regulation.
Meditation / Mindfulness
MBSR, Telomere, Stress-Reduktion und Hirnstruktur-Effekte.
Resilienz
Trainierbare Stress-Toleranz — Faktoren, Praktiken, Mindset.
St. John's Wort
Hyperizin, leichte Depression und CYP3A4-Wechselwirkungen.
BPC-157
Peptid für Geweberegeneration, Heilung und sportliche Erholung.