PregnenoloneEvidence & Dosage
Hormone precursor, memory, steroid cascade and safety.
Pregnenolone in the context of Hormones
This topic is part of our "Hormones" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to HormonesWhat we know so far about Pregnenolone
We haven't yet curated enough studies for this topic. The "Hormones" world provides the systematic context — methodology, levers, and order of operations.
Go to HormonesMore topics in Hormones
Adrenal Fatigue
A contested concept — what the evidence shows vs. how it's marketed.
Adrenal Glands
Cortisol, DHEA, adrenaline — the stress response and daily rhythm.
Adrenaline & Noradrenaline
Acute stress response, sympathetic nervous system, attention and reaction.
Chronic Stress
Allostatic load, immune and metabolic consequences, interventions.
Cortisol Daily Profile
The diurnal rhythm, CAR (cortisol awakening response), saliva measurement.
Cortisol Management
HPA axis, stress curve, adaptogens, and a healthy daily rhythm.
Cravings
Causes: blood-sugar swings, sleep deprivation, emotional eating.
Cycle Phases
Follicular phase, ovulation, luteal phase — adapting training and nutrition.
DHEA
DHEA as a precursor hormone for hormonal balance and vitality.
DHT
The most potent androgen metabolite — hair loss, prostate, libido.
Endometriosis
A chronic inflammatory disease — diagnosis, options, lifestyle factors.
Estrogen Balance
Women's optimization, aromatase, phytoestrogens, and menopause.
Free Testosterone
Bioavailable testosterone, SHBG's influence, clinical relevance.
fT3 & fT4
Free thyroid hormones — peripheral conversion and activity.
Ghrelin
Hunger hormone, sleep's influence, intermittent-fasting adaptation.
GLP-1
Glucagon-like peptide 1 — incretin, satiety, blood sugar, semaglutide's mechanism.
Growth Hormone (GH/IGF-1)
Sleep secretion, secretagogues and IGF-1 as biomarker
Hashimoto Thyroiditis
Autoimmune thyroid disease — TPO/TG antibodies, selenium, iodine caution.
Hormonal Contraception
The pill, IUD, risk profiles, side effects, alternatives.
Hormonal System
Endocrine glands, hormone axes, feedback loops — how hormones steer behavior and metabolism.
Related topics from other worlds
Training Stress
TSS, acute vs. chronic load, the ATL/CTL/TSB concept.
Apigenin (Sleep)
A flavonoid from chamomile, GABA modulation, sleep quality.
Caffeine Timing
Half-life ~5–6h — cut off 8–10h before sleep.
Glycine for Sleep
Deep sleep, lowering body temperature, and 3 g in the evening.
Lavender (Sleep)
Silexan, aromatic and oral use, sleep quality.
Sleep Architecture
REM, deep sleep, light management, and optimization strategies.