MetabolismEvidence & Dosage
Basal metabolic rate, metabolic flexibility, insulin, glucose, fat metabolism.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 50
- Meta / Systematic / RCT
- 2
- Highly cited
- 34
- Publication years
- 1995–2026
Metabolism in the context of Vitamins & Minerals
This topic is part of our "Vitamins & Minerals" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to Vitamins & MineralsTop studies on Metabolism
Ranked by influential-citation count and publication year.
Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.
Crit Rev Food Sci Nutr2003Review200 influential citationsIncreasing interest in the health benefits of tea has led to the inclusion of tea extracts in dietary supplements and functional foods. However, epidemiologic evidence regarding the effects of tea consumption on cancer and cardiovascular…
The biochemistry of programmed cell death.
FASEB J1995Review200 influential citationsProgrammed cell death (PCD) is involved in the removal of superfluous and damaged cells in most organ systems. The induction phase of PCD or apoptosis is characterized by an extreme heterogeneity of potential PCD-triggering signal…
Circadian regulation of glucose, lipid, and energy metabolism in humans.
Metabolism2018review200 influential citationsThe circadian system orchestrates metabolism in daily 24-hour cycles. Such rhythms organize metabolism by temporally separating opposing metabolic processes and by anticipating recurring feeding-fasting cycles to increase metabolic…
ROS production by mitochondria: function or dysfunction?
Oncogene2024Review200 influential citationsIn eukaryotic cells, ATP generation is generally viewed as the primary function of mitochondria under normoxic conditions. Reactive oxygen species (ROS), in contrast, are regarded as the by-products of respiration, and are widely…
The role of mitochondrial dysfunction in cardiovascular disease: a brief review.
Ann Med2018Review178 influential citationsCardiovascular disease (CVD) is a leading cause of mortality worldwide. Proper mitochondrial function is necessary in tissues and organs that are of high energy demand, including the heart. Mitochondria are very sensitive to nutrient and…
Mitochondrial aging and age-related dysfunction of mitochondria.
Biomed Res Int2014Review142 influential citationsAge-related changes in mitochondria are associated with decline in mitochondrial function. With advanced age, mitochondrial DNA volume, integrity and functionality decrease due to accumulation of mutations and oxidative damage induced by…
PINK1/Parkin-mediated mitophagy inhibits osteoblast apoptosis induced by advanced oxidation protein products.
Cell Death Dis2023Study127 influential citationsOsteoblast apoptosis plays an important role in age-related bone loss and osteoporosis. Our previous study revealed that advanced oxidation protein products (AOPPs) could induce nicotinamide adenine dinucleotide phosphate oxidase…
Redox control of cell death.
Antioxid Redox Signal2002Review98 influential citationsCellular redox is controlled by the thioredoxin (Trx) and glutathione (GSH) systems that scavenge harmful intracellular reactive oxygen species (ROS). Oxidative stress also evokes many intracellular events including apoptosis. There are…
Biomimetic copper-doped polypyrrole nanoparticles induce glutamine metabolism inhibition to enhance breast cancer cuproptosis and immunotherapy.
J Control Release202490 influential citationsCuproptosis, a newly discovered mechanism of inducing tumor cell death, primarily relies on the intracellular accumulation of copper ions. The utilization of Cu-based nanomaterials to induce cuproptosis holds promising prospects in future…
Salidroside intensifies mitochondrial function of CoCl(2)-damaged HT22 cells by stimulating PI3K-AKT-MAPK signaling pathway.
Phytomedicine2023Study83 influential citationsBACKGROUND: Salidroside (Sal), an active component from Rhodiola crenulata, has been confirmed to exert neuroprotective effects against hypoxia. However, its molecular mechanisms of intensifying mitochondrial function still largely…
Frequently asked
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Are there safety considerations for Metabolism?
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