MagnesiumEvidence & Dosage
Magnesium types, sleep, cramps, stress, and dosage.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 49
- Meta / Systematic / RCT
- 176
- Highly cited
- 50
- Publication years
- 1976–2026
Magnesium in the context of Vitamins & Minerals
This topic is part of our "Vitamins & Minerals" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to Vitamins & MineralsTop studies on Magnesium
Ranked by influential-citation count and publication year.
Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency.
Nutrients2021Review200 influential citationsMagnesium plays an important role in many physiological functions. Habitually low intakes of magnesium and in general the deficiency of this micronutrient induce changes in biochemical pathways that can increase the risk of illness and, in…
Surface modification of titanium implants with Mg-containing coatings to promote osseointegration.
Acta Biomater2023n=29Systematic Review113 influential citationsTitanium (Ti) and Ti alloys are commonly used in dental implants, which have good biocompatibility, mechanical strength, processability, and corrosion resistance. However, the surface inertia of Ti implants leads to delayed integration of…
The Role of Magnesium in Sleep Health: a Systematic Review of Available Literature.
Biol Trace Elem Res2023n=7,582systematic111 influential citationsTo date, no study has critically reviewed the current literature on the association between magnesium (Mg) and sleep health. Therefore, we carried out a systematic review to assess the association between Mg and sleep patterns in adults'…
The Role and the Effect of Magnesium in Mental Disorders: A Systematic Review.
Nutrients2020n=32Systematic Review84 influential citationsIntroduction: Magnesium is an essential cation involved in many functions within the central nervous system, including transmission and intracellular signal transduction. Several studies have shown its usefulness in neurological and…
Magnesium: Are We Consuming Enough?
Nutrients201882 influential citationsMagnesium is essential for maintaining normal cellular and organ function. In-adequate magnesium balance is associated with various disorders, such as skeletal deformities, cardiovascular diseases, and metabolic syndrome. Unfortunately,…
Mechanism of hypokalemia in magnesium deficiency.
J Am Soc Nephrol2007review80 influential citationsMagnesium deficiency is frequently associated with hypokalemia. Concomitant magnesium deficiency aggravates hypokalemia and renders it refractory to treatment by potassium. Herein is reviewed literature suggesting that magnesium deficiency…
Impact of magnesium on bone health in older adults: A systematic review and meta-analysis.
Bone2022n=787meta80 influential citationsBACKGROUND: Magnesium plays a key role in bone health and may, therefore, represent an interesting nutrient for the prevention of bone loss and osteoporosis. The aim of this systematic review and meta-analysis was to investigate the impact…
Magnesium and Cardiovascular Disease.
Adv Chronic Kidney Dis2018review74 influential citationsMagnesium is the most abundant intracellular divalent cation and essential for maintaining normal cellular physiology and metabolism, acting as a cofactor of numerous enzymes, regulating ion channels and energy generation. In the heart,…
Interventions To Attenuate Vascular Calcification Progression in Chronic Kidney Disease: A Systematic Review of Clinical Trials.
J Am Soc Nephrol2022n=689Systematic Review67 influential citationsBackground Vascular calcification is associated with cardiovascular morbidity and mortality in people with CKD. Evidence-based interventions that may attenuate its progression in CKD remain uncertain. Methods We conducted a systematic…
Effect of Magnesium Supplementation on Inflammatory Parameters: A Meta-Analysis of Randomized Controlled Trials.
Nutrients2022n=889meta64 influential citationsMagnesium (Mg) may have several beneficial effects on human health outcomes. One hypothesized mechanism eliciting such effects is the action of Mg on serum inflammatory parameters. However, studies on this topic to date have several…
Frequently asked
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Are there safety considerations for Magnesium?
Related articles
Magnesium for Regeneration - Choosing the Best Form
For fast and effective regeneration, we recommend Magnesium Glycinate or Magnesium L-Threonate. These forms are easily digestible and offer high bioavailability.
Magnesium - What are the Scientific Evidence?
Magnesium is an essential mineral that is necessary for over 300 bodily functions. It ensures normal muscle and nerve function, supports blood pressure, and helps with bone health.
Which supplements actually work? RCT check 2026
Only a handful of supplements show robust effects in randomized trials: creatine monohydrate (3-5 g/day, strength and cognition), omega-3 EPA/DHA (2-4 g/day, triglyceride reduction), magnesium (in deficiency: better sleep quality), vitamin D (when deficient, not prophylactically). Multivitamins, greens powders, and most adaptogens show no relevant effects on hard endpoints in healthy adults.
Magnesium for Better Sleep: Effects & Evidence Overview
Evidence-based overview of magnesium for sleep: What do meta-analyses and RCTs show? Which mechanisms are plausible, what remains unclear—dose & safety included.
Magnesium: Effects, Evidence, and What Is Actually Proven
Evidence-based overview of Magnesium: what studies show about effects, dosing, safety, and the limits of the data — sober and practical.
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