Schlaf

Z-DrugsStudienlage & Dosis

Zolpidem, Zopiclon — kurz wirksam, Abhängigkeitsrisiko, nicht für Daueranwendung.

Studienlage in Zahlen

Studien gesamt: 89
Mit Abstract: 32
Meta / Systematic / RCT: 0
Häufig zitiert: 4
Erscheinungsjahre: 1990–2026

Z-Drugs im Kontext von Schlaf

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Top-Studien zu Z-Drugs

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Estimated Research and Development Investment Needed to Bring a New Medicine to Market, 2009-2018.
JAMA2020n=63200 einflussreiche Zitationen
Importance The mean cost of developing a new drug has been the subject of debate, with recent estimates ranging from $314 million to $2.8 billion. Objective To estimate the research and development investment required to bring a new…
Safety of synthetic and biological DMARDs: a systematic literature review informing the 2022 update of the EULAR recommendations for the management of rheumatoid arthritis.
Annals of the rheumatic diseases2023145 einflussreiche Zitationen
<h4>Objectives</h4>To perform a systematic literature review (SLR) concerning the safety of synthetic(s) and biological (b) disease-modifying antirheumatic drugs (DMARDs) to inform the 2022 update of the EULAR recommendations for the…
Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation.
Health technology assessment (Winchester, England)200864 einflussreiche Zitationen
<h4>Objectives</h4>To review the clinical effectiveness and cost-effectiveness of cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drugs (NSAIDs) (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and…
The comparative efficacy and toxicity of second-line drugs in rheumatoid arthritis. Results of two metaanalyses.
Arthritis and rheumatism1990n=1709 einflussreiche Zitationen
We performed 2 metaanalyses of placebo-controlled and comparative clinical trials to examine the relative efficacy and toxicity of methotrexate (MTX), injectable gold, D-penicillamine (DP), sulfasalazine (SSZ), auranofin (AUR), and…
Lessons From Clinical Trials of Immunomodulatory Drugs in Psychiatric Disorders
Biological Psychiatry20261 einflussreiche Zitationen
Immune dysregulation has been implicated in the pathophysiology of psychiatric disorders, with peripheral inflammatory markers correlating with symptom severity, treatment refractoriness, and neural circuit dysfunction. This has led to…
Host-directed therapy for tuberculosis: Repurposed drugs toward global tuberculosis elimination
International Journal of Infectious Diseases20261 einflussreiche Zitationen
Despite the World Health Organization End TB Strategy, tuberculosis (TB) remains the world's leading infectious cause of death. Conventional antimicrobial therapies are hindered by prolonged treatment durations, poor patient adherence, and…
Evaluation of drugs and risk factors requiring therapeutic drug monitoring in the Neonatal Intensive Care Unit: a retrospective study
BMC Pediatrics2026
Background Neonates in the Neonatal Intensive Care Units (NICU) often receive medications requiring therapeutic drug monitoring (TDM) due to their immature organ function and the narrow therapeutic windows of these drugs. Despite its…
A universal immunocapture LC−MS/MS method for humanized IgG1−based drugs in cynomolgus monkeys
Journal of Pharmaceutical and Biomedical Analysis2026
The application of immunocapture LC-MS/MS in drug testing has expanded considerably over the past decade, offering significant advantages in analysis, development, and identification. In this study, we developed and validated a universal…
Simultaneous analysis of various anticancer drugs by supercritical fluid chromatography-mass spectrometry. Part II: Method validation and comparison with liquid chromatography
Journal of Pharmaceutical and Biomedical Analysis2026
A complete SFC-MS/MS method validation enabling the simultaneous trace-level analysis of 27 conventional anticancer drugs (CADs) was performed. The selected drugs were the following: 5-fluorouracil, azacitidine, busulfan, carboplatin,…
Retail Sales of Drugs for Diabetes, Dyslipidemia, and Hypertension in Chile Under 2 Health Policies
Value in Health Regional Issues2026
<h4>Objectives</h4>The retail market represents 60% of the pharmaceutical market in Chile. Medicines for diabetes, dyslipidemia, and hypertension are among the most commonly used by the Chilean population, and these conditions have been…