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BenzodiazepineStudienlage & Dosis

Sedativum/Hypnotikum — Abhängigkeit, kognitive Risiken im Alter.

Studien zuletzt aktualisiert 19. Mai 2026

Studienlage in Zahlen

Studien gesamt: 569
Mit Abstract: 50
Meta / Systematic / RCT: 4
Häufig zitiert: 50
Erscheinungsjahre: 1965–2026

Benzodiazepine im Kontext von Schlaf

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Top-Studien zu Benzodiazepine

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Meta-analysis of benzodiazepine use in the treatment of insomnia.
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2000n=2.672127 einflussreiche Zitationen
<h4>Objective</h4>To systematically review the benefits and risks associated with the use of benzodiazepines to treat insomnia in adults.<h4>Data sources</h4>MEDLINE and the Cochrane Controlled Trials Registry were searched for…
Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attack.
American journal of respiratory and critical care medicine2000n=116108 einflussreiche Zitationen
To investigate the prevalence and behavior of sleep-related breathing disorders (SRBDs) associated with a first-ever stroke or transient ischemic attack (TIA), we prospectively studied 161 consecutive patients admitted to our stroke unit.…
A 1,4-benzodiazepine, temazepam (K 3917), its effect on some psychological parameters of sleep and behaviour.
Arzneimittel-Forschung1975107 einflussreiche Zitationen
In 30 physically and mentally healthy volunteers, 7-chloro-1,3-dihydro-3-hydroxy-1-methyl-5-2H-1,4-benzodiazepin-2-one (temazepam, K 3917) was tested for its sleep inducing action, the subjective quality of sleep and any post-medication…
Sustained efficacy of eszopiclone over 6 months of nightly treatment: results of a randomized, double-blind, placebo-controlled study in adults with chronic insomnia.
Sleep2003n=593105 einflussreiche Zitationen
<h4>Study objectives</h4>To determine the long-term efficacy of eszopiclone in patients with chronic insomnia.<h4>Design</h4>Randomized, double-blind, multicenter, placebo-controlled.<h4>Setting</h4>Out-patient, with monthly…
Insomnia, self-medication, and relapse to alcoholism.
The American journal of psychiatry2001n=17295 einflussreiche Zitationen
<h4>Objective</h4>This study was an investigation of the frequencies of insomnia and its self-medication with alcohol in a group of alcoholic patients, as well as the relationship of these variables to alcoholic relapse.<h4>Method</h4>The…
Zolpidem: an update of its pharmacology, therapeutic efficacy and tolerability in the treatment of insomnia.
Drugs200086 einflussreiche Zitationen
<h4>Unlabelled</h4>Zolpidem is an imidazopyridine agent that is indicated for the short term (< or = 4 weeks) treatment of insomnia (recommended dosage 10 mg/day in adults and 5 or 10 mg/day in the elderly or patients with hepatic…
Abuse and dependence potential for the non-benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data.
Addiction (Abingdon, England)200378 einflussreiche Zitationen
<h4>Aims</h4>The non-benzodiazepine hypnotics zolpidem and zopiclone, which are indicated for short-term treatment of insomnia, were considered originally by physicians as almost devoid of abuse and dependence potential. Several recent…
A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease.
Sleep2003n=15772 einflussreiche Zitationen
<h4>Objectives</h4>To determine the safety and efficacy of 2 dose formulations of melatonin for the treatment of insomnia in patients with Alzheimer's disease.<h4>Design</h4>A multicenter, randomized, placebo-controlled clinical trial of 2…
Alcohol's effects on sleep in alcoholics.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism2001n=74869 einflussreiche Zitationen
Sleep problems, which can have significant clinical and economic consequences, are more common among alcoholics than among nonalcoholics. During both drinking periods and withdrawal, alcoholics commonly experience problems falling asleep…
Randomized clinical trial of supervised tapering and cognitive behavior therapy to facilitate benzodiazepine discontinuation in older adults with chronic insomnia.
The American journal of psychiatry2004n=3868 einflussreiche Zitationen
<h4>Objective</h4>This study evaluated the effectiveness of a supervised benzodiazepine taper, singly and combined with cognitive behavior therapy, for benzodiazepine discontinuation in older adults with chronic…

Häufige Fragen

Welche Dosierung wurde in den Studien untersucht?

• benzodiazepines

Gibt es Sicherheitshinweise zu Benzodiazepine?

• more patients receiving benzodiazepine treatment reported adverse effects, especially daytime drowsiness and dizziness or light-headedness (common odds ratio 1.8, 95% CI 1.4 to 2.4)