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Rhodiola RoseaEvidence & Dosage

Adaptogen, salidroside, burnout and stress resilience.

Studies last updated

Evidence at a glance

Total studies
784
With abstract
50
Meta / Systematic / RCT
73
Highly cited
50
Publication years
1986–2026

Rhodiola Rosea in the context of Cognition

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Top studies on Rhodiola Rosea

Ranked by influential-citation count and publication year.

  1. Salidroside: An Overview of Its Promising Potential and Diverse Applications.

    Pharmaceuticals (Basel)2024Review84 influential citations

    Salidroside, a phenolic compound isolated from various <i>Rhodiola</i> plants, is the principal active constituent of Traditional Chinese Medicine known for its adaptogenic properties. Due to the challenging environment of <i>Rhodiola</i>…

  2. Rhodiola species: A comprehensive review of traditional use, phytochemistry, pharmacology, toxicity, and clinical study.

    Medicinal research reviews2019D74 influential citations

    Rhodiola species, belonging to the family Crassulaceae, have long been used as an adaptogen, tonic, antidepressant, and antistress medicine or functional food in Asia and Europe. Due to the valuable application, the growing demand of…

  3. Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.

    Phytomedicine2000n=56RCT56 influential citations

    The aim of this study was to investigate the effect of repeated low-dose treatment with a standardized extract SHR/5 of rhizome Rhodiola rosea L, (RRE) on fatigue during night duty among a group of 56 young, healthy physicians. The effect…

  4. Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression.

    Nord J Psychiatry2007n=89RCT51 influential citations

    The objective of this study was to assess the efficacy and safety of standardized extract SHR-5 of rhizomes of Rhodiola rosea L. in patients suffering from a current episode of mild/moderate depression. The phase III clinical trial was…

  5. A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.

    Phytomedicine2000RCT49 influential citations

    The objective was to investigate the stimulating and normalizing effect of the adaptogen Rhodiola rosea extract SHR-5 in foreign students during a stressful examination period. The study was performed as a double-blind, randomized and…

  6. Efficient Biosynthesis of Salidroside via Artificial in Vivo enhanced UDP-Glucose System Using Cheap Sucrose as Substrate.

    ACS Omega2024Study42 influential citations

    Salidroside, a valuable phenylethanoid glycoside, is obtained from plants belonging to the <i>Rhodiola</i> genus, known for its diverse biological properties. At present, salidroside is still far from large-scale industrial production due…

  7. A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.

    Planta Med2009n=60RCT41 influential citations

    The aim of the study was to assess the efficacy of the standardised extract SHR-5 of roots of Rhodiola Rosea L. in the treatment of individuals suffering from stress-related fatigue. The phase III clinical trial took the form of a…

  8. A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work.

    Phytomedicine2003n=161RCT39 influential citations

    A randomized, double-blind, placebo-controlled, parallel-group clinical study with an extra non-treatment group was performed to measure the effect of a single dose of standardized SHR-5 Rhodiola rosea extract on capacity for mental work…

  9. Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.

    Phytomedicine2015n=57RCT35 influential citations

    <h4>Background</h4>We performed a proof of concept trial to evaluate relative safety and efficacy of Rhodiola rosea (R. rosea) versus sertraline for mild to moderate major depressive disorder.<h4>Hypothesis</h4>We hypothesize that R. rosea…

  10. Effects of the Combined Supplementation of Caffeine and Rhodiola Rosea with Resistance Training on Lower Limb Explosive Power in Male Volleyball Players.

    Nutrients2025n=48RCT32 influential citations

    <h4>Background</h4>This study investigated the effects of combined Rhodiola rosea (RHO) and caffeine (CAF) supplementation on lower limb explosive power and fatigue recovery in volleyball players, aiming to validate their potential…

Frequently asked

What dosage was studied?
• Salidroside (not reported) • Rhodiola species • Standardized extract SHR-5 of Rhodiola rosea L. rhizome (RRE) (One tablet daily)
Are there safety considerations for Rhodiola Rosea?
• Safety is discussed in the review, but no specific adverse events are reported in the abstract. • No side-effects were reported for either treatment. • No serious side-effects were reported in groups A-C. • Not reported.

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