Insulin ResistanceEvidence & Dosage
Glucose tolerance, HbA1c, CGM, and lifestyle interventions.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 50
- Meta / Systematic / RCT
- 163
- Highly cited
- 24
- Publication years
- 1978–2026
Insulin Resistance in the context of Hormones
This topic is part of our "Hormones" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to HormonesTop studies on Insulin Resistance
Ranked by influential-citation count and publication year.
The metabolic syndrome and mortality from cardiovascular disease and all-causes: findings from the National Health and Nutrition Examination Survey II Mortality Study.
Atherosclerosis2004101 influential citationsThe prospective associations between the metabolic syndrome as defined by the National Cholesterol Education Program (NCEP/ATP III) expert panel and mortality from cardiovascular disease and all-causes has not been extensively examined.…
Cumulative increased risk of incident type 2 diabetes mellitus with increasing triglyceride glucose index in normal-weight people: The Rural Chinese Cohort Study.
Cardiovascular diabetology2017n=20,19496 influential citations<h4>Background</h4>Risk of type 2 diabetes mellitus (T2DM) is increased in metabolically obese but normal-weight people. However, we have limited knowledge of how to prevent T2DM in normal-weight people. We aimed to evaluate the…
Increased risk of diabetes with statin treatment is associated with impaired insulin sensitivity and insulin secretion: a 6 year follow-up study of the METSIM cohort.
Diabetologia2015n=62588 influential citations<h4>Aims/hypothesis</h4>The aim of this work was to investigate the mechanisms underlying the risk of type 2 diabetes associated with statin treatment in the population-based Metabolic Syndrome in Men (METSIM) cohort.<h4>Methods</h4>A…
The Impact of Dietary Interventions on Metabolic Outcomes in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) and Comorbid Conditions, Including Obesity and Type 2 Diabetes.
Nutrients2025n=926systematic67 influential citationsBackground: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a public health concern, linked with immune-metabolic dysfunction. While lifestyle and dietary modifications remain the cornerstone of MASLD management, the…
Global prevalence of metabolic dysfunction-associated fatty liver disease in children and adolescents with overweight and obesity: a systematic review and meta-analysis.
BMC Gastroenterol2025n=57,058Meta-Analysis52 influential citations<h4>Background</h4>The prevalence of Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) among children and adolescents with overweight and/or obesity is rising globally, reflecting increasing obesity rates and metabolic syndrome.…
Finding: Among children and adolescents with overweight and/or obesity, the global prevalence of MAFLD was 41.2%.
The Effect of Aerobic or Resistance Exercise Combined With a Low-Calorie Diet Versus Diet Alone on Cardiometabolic Outcomes in Adults with Overweight and Obesity: A Systematic Review and Meta-Analysis.
Nutr Rev2026n=97Meta-Analysis50 influential citations<h4>Context</h4>Individual studies examining the combined effects of exercise and a low-calorie diet on cardiometabolic factors have yielded inconsistent results.<h4>Objective</h4>In this systematic review and meta-analysis of randomized…
Comparison of the Mediterranean Diet and Other Therapeutic Strategies in Metabolic Syndrome: A Systematic Review and Meta-Analysis.
Int J Mol Sci2025n=12Meta-Analysis47 influential citationsThe Mediterranean diet (MD) is one of the healthiest diets, high in fiber, antioxidants, and unsaturated fats. MD improves lipid profiles, reduces inflammation, controls blood pressure, decreases insulin resistance, and enhances the…
Cardiometabolic and obesity risk outcomes of dawn-to-dusk, dry intermittent fasting: Insights from an umbrella review.
Clin Nutr ESPEN2025n=3,456Meta-Analysis43 influential citations<h4>Background & aims</h4>This umbrella review comprehensively and systematically summarizes meta-analyses on the impact of dawn-to-dusk, dry intermittent fasting of Ramadan (RIF) on cardiometabolic and glucose homeostasis…
Finding: The review concludes that dawn-to-dusk, dry Ramadan intermittent fasting shows promise as a complementary therapy and preventive measure for reducing cardiometabolic and obesity-related risks.
Inappropriate Diet Exacerbates Metabolic Dysfunction-Associated Steatotic Liver Disease via Abdominal Obesity.
Nutrients2024Systematic Review40 influential citationsMetabolic dysfunction-associated steatotic liver disease (MASLD) represents a refined categorization of non-alcoholic fatty liver disease (NAFLD), highlighting the intricate relationship between hepatic steatosis and metabolic dysfunction.…
Prevalence of subclinical hypothyroidism in polycystic ovary syndrome and its impact on insulin resistance: a systematic review and meta-analysis.
BMC Endocr Disord2025n=576Meta-Analysis36 influential citations<h4>Background</h4>Although recent studies indicate a high prevalence of subclinical hypothyroidism (SCH) in women with polycystic ovary syndrome (PCOS), the reported prevalence rates vary widely. Therefore, we conducted this study to…
Frequently asked
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