Restless LegsStudienlage & Dosis
Eisen, Dopamin-Hypothese, Lifestyle-Faktoren.
Studienlage in Zahlen
- Studien gesamt
- 1.000
- Mit Abstract
- 50
- Meta / Systematic / RCT
- 152
- Häufig zitiert
- 50
- Erscheinungsjahre
- 1989–2026
Restless Legs im Kontext von Schlaf
Dieses Thema ist Teil unserer Welt „Schlaf". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.
Zur Welt SchlafTop-Studien zu Restless Legs
Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.
Sleep disturbances during pregnancy and adverse maternal and fetal outcomes: A systematic review and meta-analysis.
Sleep Med Rev2021n=58.123.250meta200 einflussreiche ZitationenSleep disturbances are highly prevalent in pregnancy and are frequently overlooked as a potential cause of significant morbidity. The association between sleep disturbances and pregnancy outcomes remains largely controversial and needs to…
Worldwide estimation of restless legs syndrome: a systematic review and meta-analysis of prevalence in the general adult population.
J Sleep Res2023Meta-Analysis148 einflussreiche ZitationenSummary This systematic review, meta‐analysis and meta‐regression assessed the prevalence of restless legs syndrome (RLS) in the general adult population. Studies identified in Scopus, PubMed, Web of Science, and PsycInfo between January…
Restless legs syndrome associated with major diseases: A systematic review and new concept.
Neurology2016Systematic Review139 einflussreiche ZitationenRecent publications on both the genetics and environmental factors of restless legs syndrome (RLS) defined as a clinical disorder suggest that overlapping genetic risk factors may play a role in primary (idiopathic) and secondary…
Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis.
Sleep Med2018n=37Meta-Analysis129 einflussreiche Zitationen<h4>Objectives</h4>Chronic pain, with or without an identified diagnosis or cause, is widespread and commonly associated with sleep disturbances. However, research has often used poor quality measures of sleep and focused on specific pain…
Sleep disorders and non-sleep circadian disorders predict depression: A systematic review and meta-analysis of longitudinal studies.
Neurosci Biobehav Rev2022Meta-Analysis123 einflussreiche ZitationenPatients with depression often suffer from sleep disorders and non-sleep circadian disorders. However, whether they precede and predict subsequent depression is unclear. We conducted a meta-analysis of studies on sleep disorders and…
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.
Nat Genet2024n=116.647Meta-Analysis123 einflussreiche ZitationenRestless legs syndrome (RLS) affects up to 10% of older adults. Their healthcare is impeded by delayed diagnosis and insufficient treatment. To advance disease prediction and find new entry points for therapy, we performed meta-analyses of…
A systematic review of the literature on disorders of sleep and wakefulness in Parkinson's disease from 2005 to 2015.
Sleep Med Rev2017Systematic Review122 einflussreiche ZitationenSleep disorders are among the most common non-motor manifestations in Parkinson's disease (PD) and have a significant negative impact on quality of life. While sleep disorders in PD share most characteristics with those that occur in the…
Sleep Disorders in Cancer-A Systematic Review.
Int J Environ Res Public Health2021n=89systematic100 einflussreiche ZitationenINTRODUCTION: Sleep disorders, especially insomnia, are very common in different kinds of cancers, but their prevalence and incidence are not well-known. Disturbed sleep in cancer is caused by different reasons and usually appears as a…
Sleep disorders increase the risk of dementia, Alzheimer's disease, and cognitive decline: a meta-analysis.
Geroscience2025n=39Meta-Analysis93 einflussreiche ZitationenSleep disorders, particularly insomnia and obstructive sleep apnea, are increasingly implicated as significant contributors to cognitive decline, dementia, and neurodegenerative diseases such as Alzheimer's disease (AD) and vascular…
Genome-wide association analysis of self-reported daytime sleepiness identifies 42 loci that suggest biological subtypes.
Nat Commun2019n=452.071Meta-Analysis89 einflussreiche ZitationenExcessive daytime sleepiness (EDS) affects 10–20% of the population and is associated with substantial functional deficits. Here, we identify 42 loci for self-reported daytime sleepiness in GWAS of 452,071 individuals from the UK Biobank,…
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Weitere Themen in Schlaf
Glycin
Glycin, Schlafqualität, Körpertemperatur und Sicherheit.
Alkohol & Schlaf
Schnelleres Einschlafen, aber REM-Suppression und Wach-Phasen.
Antihistaminika
Diphenhydramin, Doxylamin — Schlaf-Frags, anticholinerge Demenz-Risiken.
Apigenin
Kamille, GABA-Modulation und Schlafqualität.
Apigenin (Schlaf)
Flavonoid aus Kamille, GABA-Modulation, Schlafqualität.
Ashwagandha (Schlaf)
Cortisol-Senkung, Schlafqualität — KSM-66 und Sensoril-Extrakte.
Dunkelheit
Blackout-Vorhänge, Schlafmaske — Melatonin und Schlaftiefe.
Raumtemperatur
Optimal 17-19°C — Körperkerntemperatur-Abfall fördert Schlaf.
Benzodiazepine
Sedativum/Hypnotikum — Abhängigkeit, kognitive Risiken im Alter.
Blaulichtfilter
f.lux, Night Shift, Brillen — Evidenz und Marketing-Hype.
Bruxismus
Zähneknirschen — Stress, Schiene, Trigger-Faktoren.
Koffein-Timing
Halbwertszeit ~5-6h — Cut-off 8-10h vor Schlaf.
CBD for Sleep
Endocannabinoid-System, REM-Effekte und Dosierungs-Spektrum.
CBT-I
Kognitive Verhaltenstherapie für Insomnie — Erstlinien-Therapie laut Leitlinie.
Circadianer Rhythmus
Innere ~24h-Uhr — Licht als Hauptsignal, periphere Uhren in Organen.
CPAP
Continuous Positive Airway Pressure — Standard bei mittelschwerer Apnoe.
Tiefschlaf
N3-Slow-Wave-Sleep — körperliche Regeneration, GH-Ausschüttung.
GABA Supplements
Blut-Hirn-Schranke, fermentiertes GABA und Wirksamkeits-Daten.
Glycine for Sleep
Tiefschlaf, Körpertemperatur-Senkung und 3g abends.
Glycin (Schlaf)
3g vor dem Schlaf — Körperkerntemperatur-Senkung, Tiefschlaf-Modulation.
Verwandte Themen aus anderen Welten
ATP-System
Phosphagen-System, anaerobe Glykolyse, oxidative Phosphorylierung.
Deload
Geplante Erholungsphasen — Vermeidung von Overreaching.
HMB
Sarkopenie, Anti-Catabolisch und Sport-Anwendungen.
Nitrat
Stickoxid-Vorläufer, Ausdauer-Performance, Blutdruck-Senkung.
SARMs
Selektive Androgen-Rezeptor-Modulatoren — Doping, Off-Label, Leberrisiko.
VO2max Training
Intervalle, VO2max, kardiovaskuläre Spitze und Protokolle.