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Anabolic SteroidsEvidence & Dosage

Anabolic steroids — medical and doping aspects, risks.

Evidence at a glance

Total studies
867
With abstract
44
Meta / Systematic / RCT
3
Highly cited
0
Publication years
1960–2026

Anabolic Steroids in the context of Performance

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Top studies on Anabolic Steroids

Ranked by influential-citation count and publication year.

  1. Anabolic-Androgenic Steroids Induced Cardiomyopathy: A Narrative Review of the Literature.

    Biomedicines2025n=59,450D2 influential citations

    Anabolic-androgenic steroids (AASs) are synthetic derivatives of testosterone and are increasingly misused to enhance muscle growth and physical performance, particularly among athletes and recreational bodybuilders. Although AASs affect…

  2. Effects of growth hormone and anabolic steroids, in critically ill patients admitted to the intensive care unit: a systematic review and meta-analysis.

    Sci Rep2025n=172Meta-Analysis2 influential citations

    This study aimed to review the effects of performance enhancing drugs (PEDs), such as anabolic steroids, on clinical outcomes in critically ill patients. A systematic review and meta-analysis of randomized controlled trials comparing any…

    Finding: In critically ill ICU patients, growth hormone improved nitrogen balance.

  3. Impact of Anabolic Steroids on Tendons: A Narrative Review.

    Cureus2025n=5,773D1 influential citations

    Anabolic-androgenic steroids (AAS), synthetic testosterone derivatives, are used to increase muscle mass and performance. However, high doses negatively affect tendons and ligaments, disrupting collagen balance and increasing injury risk…

  4. Anabolic-Androgenic Steroids Revisited: Structural Biology, Receptor Signaling, and Mechanisms of Anabolic-Androgenic Dissociation.

    International journal of molecular sciences2026D

    Steroid hormones exert diverse and tissue-specific biological effects despite sharing a conserved tetracyclic scaffold. Among these, anabolic-androgenic steroids (AAS) present a longstanding paradox: structurally related compounds can…

  5. Androgen Use Among Female Amateur Athletes: A Retrospective Analysis.

    Scandinavian journal of medicine & science in sports2026E

    Most research on non-prescribed androgen use has focused on men, while women remain underrepresented in the literature, despite unique risks such as virilization and reproductive consequences. This is one of the largest described cohorts…

  6. Ginseng nanoparticles mitigate boldenone-induced testicular oxidative damage and reproductive dysfunction in adult male rats.

    Tissue & cell2026E

    The widespread misuse of anabolic androgenic steroids (AAS), Such as boldenone undecylenate (Bold), poses significant risks to male reproductive health through oxidative stress and androgen receptor dysregulation. This study evaluated the…

  7. Paternal anabolic-androgenic steroid exposure promotes autism-like behavior in adult mouse offspring of both sexes.

    Hormones and behavior2026E

    Paternal environmental factors before conception and during sperm development may influence the offspring's health later in life. This study aimed to investigate whether paternal exposure to anabolic-androgenic steroids (AAS) before…

  8. Effects of repeated administration of oxandrolone in female wistar rats undergoing strength training.

    2026n=12

    Anabolic androgenic steroids are synthetic derivatives of testosterone that mimic its actions in various tissues. Due to its strong anabolic activity, weak androgenic effects, and resistance to hepatic metabolism, oxandrolone is one of the…

  9. Muscle pain in a woman with congenital adrenal hyperplasia due to 21-hydroxylase deficiency resolved with testosterone therapy. A case report with 10 years of follow-up.

    Frontiers in endocrinology2026E

    Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) requires lifelong glucocorticoid (GC) and mineralocorticoid therapy to prevent adrenal crises and control androgen excess. However, chronic GC overtreatment may…

  10. Non-medical use of exogenous testosterone and anabolic-androgenic substances in young men: health, psychological, and fertility consequences.

    Frontiers in endocrinology2026D

    The non-medical use of exogenous testosterone and other anabolic-androgenic steroids (AAS) has increased substantially in recent years, particularly among young men engaged in recreational strength training. Although often perceived as a…

Frequently asked

What dosage was studied?
• Growth hormone, nandrolone, and oxandrolone (performance enhancing drugs) (Varied by study; GH dosages between 0.05 and 0.30 mg/kg/day; other PED doses not pooled)
Are there safety considerations for Anabolic Steroids?
• RhGH frequently caused hyperglycemia, sometimes needing more insulin. • Oxandrolone was linked to higher alanine and aspartate aminotransferases. • Nandrolone caused slight LDL and triglyceride increases in one study.

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