AmphetaminesEvidence & Dosage

Top studies on Amphetamines

Ranked by influential-citation count and publication year.

1. 01

   Effects of terguride, ropinirole, and acetyl-L-carnitine on methamphetamine withdrawal in the rat.

   Pharmacology, biochemistry, and behavior·2006E9 influential citations

   Withdrawal from psychostimulants, including methamphetamine, induces a depressive state associated with lethargy, dysphoria, hyperphagia and psychomotor retardation. Previous work with repeated administration of amphetamine in rats has…

2. 02

   Safety and tolerability of N-acetylcysteine in cocaine-dependent individuals.

   The American journal on addictions·20067 influential citations

   A double-blind placebo-controlled crossover Phase I trial was conducted to assess the safety and tolerability of N-Acetylcysteine (NAC) in healthy, cocaine-dependent humans. Thirteen participants attended a three-day hospitalization in…

3. 03

   In vitro inhibition of monoamine transport by amphetamine-like pre-workout supplement ingredients.

   Toxicology·2026E

   Phenethylamine (PEA) and alkylamine (AA) analogues are a prominent group of pre-workout food supplement ingredients. They are structurally related to the stimulant amphetamine and to the endogenous catecholamines noradrenaline and…

4. 04

   Temporal trends in the burden of drug use disorders in East and Southeast Asian countries and territories from 1990 to 2021: findings from the Global Burden of Disease Study 2021.

   The American journal of drug and alcohol abuse·2026

   <i>Background:</i> East and Southeast Asia face a severe drug epidemic. A detailed analysis of specific drug use disorders (DUDs) is urgently needed to inform targeted interventions.<i>Objective:</i> To quantify trends in the burden of…

5. 05

   Enhanced effect of the hallucinogen DOI in L-DOPA receptor Gpr143-deficient mice.

   Journal of pharmacological sciences·2026

   Hallucinogens, such as lysergic acid diethylamide, act primarily through the 5-hydroxytryptamine 2A (5-HT2A) receptor, but their regulatory mechanisms remain unclear. G protein-coupled receptor 143 (GPR143), an L-3,4-dihydroxyphenylalanine…

6. 06

   Prenatal methamphetamine exposure increased addiction vulnerability through neural circuit dysfunction and epigenetic modifications in offspring.

   Neurotoxicology and teratology·2026

   Methamphetamine (METH), a type of synthetic drug with effects similar to amphetamines, remains a significant public health concern, particularly among women of childbearing age. Prenatal methamphetamine exposure (PME) has been demonstrated…

7. 07

   Childhood Maltreatment and Drug Craving in Patients With Methamphetamine Use Disorder: The Independent and Serial Mediating Roles of Emotional Dysregulation and Impulsivity.

   Clinical psychology &amp; psychotherapy·2026

   Growing evidence suggests that childhood maltreatment (CM) is associated with adverse emotional and behavioural outcomes in individuals with methamphetamine use disorder (MUD). However, the psychological mechanisms underlying the…

8. 08

   Methamphetamine Use Among Adult Patients Presenting With Acute Coronary Syndrome: A Single-Center Retrospective Cohort Study.

   Journal of the American Heart Association·2026·n=1,115

   <h4>Background</h4>Methamphetamine-associated acute coronary syndrome (ACS) has not been previously well studied.<h4>Methods</h4>This retrospective, single-center study included all patients aged 18 to 65 years who presented with ACS and…

9. 09

   Ketamine enhancement of dexmedetomidine attenuation of methamphetamine-induced agitation in rats.

   Journal of pharmacy &amp; pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques·2026

   Methamphetamine (METH)-induced agitation, a major concern in acute METH intoxication, is currently treated with benzodiazepines. Due to current polysubstance use patterns in METH consumption, this treatment may fatally exacerbate…

10. 10

    Stimulant Medications and Bone Health.

    Curr Osteoporos Rep·2026Review

    <h4>Purpose of review</h4>This review summarizes the potential impact of stimulant medications on bone health, to raise awareness and optimize their safe use.<h4>Recent findings</h4>Stimulant medications can impair bone health through…