DepressionEvidence & Dosage
Symptoms, the monoamine hypothesis, lifestyle interventions, professional help.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 46
- Meta / Systematic / RCT
- 16
- Highly cited
- 44
- Publication years
- 1946–2026
Depression in the context of Mental
This topic is part of our "Mental" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to MentalTop studies on Depression
Ranked by influential-citation count and publication year.
A new depression scale designed to be sensitive to change.
The British journal of psychiatry : the journal of mental science1979n=64200 influential citationsThe construction of a depression rating scale designed to be particularly sensitive to treatment effects is described. Ratings of 54 English and 52 Swedish patients on a 65 item comprehensive psychopathology scale were used to identify the…
The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories.
Behaviour research and therapy1995n=717200 influential citationsThe psychometric properties of the Depression Anxiety Stress Scales (DASS) were evaluated in a normal sample of N = 717 who were also administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI). The DASS was shown…
Comparison of Beck Depression Inventories -IA and -II in psychiatric outpatients.
Journal of personality assessment1996200 influential citationsThe amended (revised) Beck Depression Inventory (BDI-IA; Beck & Steer, 1993b) and the Beck Depression Inventory-II (BDI-II; Beck, Steer, & Brown, 1996) were self-administered to 140 psychiatric outpatients with various psychiatric…
Screening for depression in well older adults: evaluation of a short form of the CES-D (Center for Epidemiologic Studies Depression Scale).
American journal of preventive medicine1994200 influential citationsWe derived and tested a short form of the Center for Epidemiologic Studies Depression Scale (CES-D) for reliability and validity among a sample of well older adults in a large Health Maintenance Organization. The 10-item screening…
Depression, chronic diseases, and decrements in health: results from the World Health Surveys.
Lancet (London, England)2007n=404200 influential citations<h4>Background</h4>Depression is an important public-health problem, and one of the leading causes of disease burden worldwide. Depression is often comorbid with other chronic diseases and can worsen their associated health outcomes. Few…
Reciprocal limbic-cortical function and negative mood: converging PET findings in depression and normal sadness.
The American journal of psychiatry1999200 influential citations<h4>Objective</h4>Theories of human behavior from Plato to Freud have repeatedly emphasized links between emotion and reason, a relationship now commonly attributed to pathways connecting phylogenetically "old" and "new" brain regions.…
The Hospital Anxiety And Depression Scale.
Health and quality of life outcomes2003200 influential citationsThere is a need to assess the contribution of mood disorder, especially anxiety and depression, in order to understand the experience of suffering in the setting of medical practice. Most physicians are aware of this aspect of the illness…
Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus.
Biological psychiatry2007n=28200 influential citations<h4>Background</h4>Positron emission tomography (PET) studies of major depression have revealed resting-state abnormalities in the prefrontal and cingulate cortices. Recently, fMRI has been adapted to examine connectivity within a specific…
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action.
Nature neuroscience2006200 influential citationsTo better understand the molecular mechanisms of depression and antidepressant action, we administered chronic social defeat stress followed by chronic imipramine (a tricyclic antidepressant) to mice and studied adaptations at the levels…
Epidemiology of women and depression.
Journal of affective disorders2003200 influential citations<h4>Background</h4>Depression is the leading cause of disease-related disability among women in the world today. Depression is much more common among women than men, with female/male risk ratios roughly 2:1.<h4>Aims</h4>Recent…
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