AnxietyEvidence & Dosage
Acute anxiety vs. an anxiety disorder, the neurobiology, interventions.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 43
- Meta / Systematic / RCT
- 16
- Highly cited
- 19
- Publication years
- 1952–2026
Anxiety in the context of Mental
This topic is part of our "Mental" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to MentalTop studies on Anxiety
Ranked by influential-citation count and publication year.
The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck Depression and Anxiety Inventories.
Behaviour research and therapy1995n=717200 influential citationsThe psychometric properties of the Depression Anxiety Stress Scales (DASS) were evaluated in a normal sample of N = 717 who were also administered the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI). The DASS was shown…
Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region.
Science (New York, N.Y.)1996n=505200 influential citationsTransporter-facilitated uptake of serotonin (5-hydroxytryptamine or 5-HT) has been implicated in anxiety in humans and animal models and is the site of action of widely used uptake-inhibiting antidepressant and antianxiety drugs. Human…
The Hospital Anxiety And Depression Scale.
Health and quality of life outcomes2003200 influential citationsThere is a need to assess the contribution of mood disorder, especially anxiety and depression, in order to understand the experience of suffering in the setting of medical practice. Most physicians are aware of this aspect of the illness…
Psychometric properties of the Depression Anxiety Stress Scales (DASS) in clinical samples.
Behaviour research and therapy1997n=437200 influential citationsThe psychometric properties of the Depression Anxiety Stress Scales (DASS) were evaluated in two studies using large clinical samples (N = 437 and N = 241). In Study 1, the three scales comprising the DASS were shown to have excellent…
Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer.
Arch Gen Psychiatry2011rct200 influential citationsCONTEXT: Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a…
Placebo effects in randomized trials of pharmacological and neurostimulation interventions for mental disorders: An umbrella review.
Mol Psychiatry2024n=261,730Systematic Review54 influential citationsThere is a growing literature exploring the placebo response within specific mental disorders, but no overarching quantitative synthesis of this research has analyzed evidence across mental disorders. We carried out an umbrella review of…
Anxiety, depression, impulsivity, and brain structure in children and adolescents.
Neuroimage Clin2018n=32845 influential citationsThe unique neuroanatomical underpinnings of internalizing symptoms and impulsivity during childhood are not well understood. In this study, we examined associations of brain structure with anxiety, depression, and impulsivity in children…
The effect of SSRIs on unconditioned anxiety: a systematic review and meta-analysis of animal studies.
Psychopharmacology (Berl)2024n=105Meta-Analysis33 influential citations<h4>Rationale</h4>Selective serotonin reuptake inhibitors (SSRIs) are the first choice of treatment for anxiety-like disorders. However, which aspects of anxiety are affected by SSRIs is not yet fully understood.<h4>Objective</h4>We aimed…
Finding: SSRIs reduce anxiety-like behaviour in the elevated plus maze, marble burying and ultrasonic vocalization test.
Complementary and alternative therapies as add-on to pharmacotherapy for mood and anxiety disorders: a systematic review.
J Affect Disord2013Systematic Review30 influential citations<h4>Background</h4>Depressed and anxious patients often combine complementary and alternative medicine (CAM) therapies with conventional pharmacotherapy to self-treat symptoms. The benefits and risks of such combination strategies have not…
Clinical effectiveness of pharmacological and non-pharmacological treatments for the management of anxiety in community dwelling people living with dementia: A systematic review and meta-analysis.
Neurosci Biobehav Rev2024n=31Meta-Analysis30 influential citationsPeople living with dementia commonly experience anxiety, which is often challenging to manage. We investigated the effectiveness of treatments for the management of anxiety in this population. We conducted a systematic review and…
Finding: Non-pharmacological interventions were effective in reducing anxiety in people living with dementia compared with care as usual or active controls.
Frequently asked
Which population does the evidence apply to?
Are there safety considerations for Anxiety?
More topics in Mental
5-HTP
Serotonin precursor, mood, and Carbidopa safety.
Ashwagandha (Stress)
Adaptogen — cortisol lowering, sleep, anxiety reduction.
Breathwork
Box breathing, 4-7-8, Wim Hof, pranayama — autonomic regulation.
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Exhaustion, cynicism, dropping performance — spotting it before the crash.
Caffeine & Anxiety
Adenosine antagonism, individual sensitivity, cut-off strategies.
CBT
Cognitive behavioral therapy — the gold standard for anxiety and depression.
Co-Regulation
Nervous-system regulation within relationship — attachment, therapy, parent-child.
Cold Exposure (Mood)
Norepinephrine, depression, and mood effects of cold.
Depression
Symptoms, the monoamine hypothesis, lifestyle interventions, professional help.
Depth Psychology
Psychodynamic therapy, transference, long-term change.
Doomscrolling
Algorithm-driven negative info consumption — mood effects, limits.
EMDR / Trauma Therapy
PTSD, eye movements, and study effectiveness.
Exercise as Antidepressant
Aerobic exercise — efficacy comparable to SSRIs in mild depression.
Fight/Flight/Freeze
Stress-response patterns, somatic manifestation, regulation.
Glucose & Mood
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Gut-Brain Axis
Vagus nerve, short-chain fatty acids, the microbiome's influence on mood.
Journaling (Mental)
Expressive writing, gratitude — reducing stress, anxiety and depression.
L-Tryptophan
Serotonin/Melatonin, amino‑acid competition and outcomes.
Lavender
Silexan studies, oral and olfactory — anxiolysis with a good safety profile.
Meditation
Mindfulness, concentration, loving-kindness meditation — effects and practice.
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