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Glucose & MoodEvidence & Dosage

Glucose swings, reactive hypoglycemia, mood stability.

Evidence at a glance

Total studies
120
With abstract
46
Meta / Systematic / RCT
2
Highly cited
16
Publication years
1988–2026

Glucose & Mood in the context of Mental

This topic is part of our "Mental" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

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Top studies on Glucose & Mood

Ranked by influential-citation count and publication year.

  1. Impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia.

    The American journal of psychiatry2003174 influential citations

    <h4>Objective</h4>This study examined the prevalence of impaired fasting glucose tolerance in first-episode, drug-naive patients with schizophrenia.<h4>Method</h4>In this cross-sectional study, fasting plasma levels of glucose, insulin,…

  2. Acute and long-term effects of Roux-en-Y gastric bypass on glucose metabolism in subjects with Type 2 diabetes and normal glucose tolerance.

    American journal of physiology. Endocrinology and metabolism201284 influential citations

    Our aim was to study the potential mechanisms responsible for the improvement in glucose control in Type 2 diabetes (T2D) within days after Roux-en-Y gastric bypass (RYGB). Thirteen obese subjects with T2D and twelve matched subjects with…

  3. Empagliflozin Improves Insulin Sensitivity of the Hypothalamus in Humans With Prediabetes: A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Trial.

    Diabetes care2022n=4072 influential citations

    OBJECTIVE Insulin action in the human brain reduces food intake, improves whole-body insulin sensitivity, and modulates body fat mass and its distribution. Obesity and type 2 diabetes are often associated with brain insulin resistance,…

  4. Increased prevalence of type 2 diabetes mellitus among psychiatric inpatients with bipolar I affective and schizoaffective disorders independent of psychotropic drug use.

    Journal of affective disorders200268 influential citations

    <h4>Background</h4>There are numerous reports of abnormal glucose metabolism, including increased rates of type 2 diabetes mellitus, in psychiatric patients. It remains unclear, however, whether there is an intrinsic relationship between…

  5. Relationships Between Brain Glucose Metabolism Patterns and Impaired Glycemic Status: A Systematic Review of FDG-PET Studies With a Focus on Alzheimer's Disease.

    Human brain mapping2025n=5,30863 influential citations

    It is well-established that individuals with type 2 diabetes have an increased risk of developing cognitive impairment and Alzheimer's disease (AD). However, it is not fully determined how insulin resistance and type 2 diabetes are related…

  6. High-fat diet-induced metabolic disorders impairs 5-HT function and anxiety-like behavior in mice.

    British journal of pharmacology201661 influential citations

    Background and Purpose The link between type 2 diabetes mellitus (T2DM) and depression is bidirectional. However, the possibility that metabolic disorders may elicit anxiogenic‐like/depressive‐like symptoms or alter the efficacy of…

  7. Insulin resistance after oral glucose tolerance testing in patients with major depression.

    The American journal of psychiatry198858 influential citations

    An association between affective disorders and alterations in glucose utilization has been recognized. The authors administered a 5-hour oral glucose tolerance test (GTT) to 28 depressed patients and 21 healthy volunteer control subjects…

  8. Circulating glucose levels modulate neural control of desire for high-calorie foods in humans.

    The Journal of clinical investigation201151 influential citations

    Obesity is a worldwide epidemic resulting in part from the ubiquity of high-calorie foods and food images. Whether obese and nonobese individuals regulate their desire to consume high-calorie foods differently is not clear. We set out to…

  9. Depression, anxiety and glucose metabolism in the general dutch population: the new Hoorn study.

    PloS one2010n=6,18030 influential citations

    <h4>Background</h4>There is a well recognized association between depression and diabetes. However, there is little empirical data about the prevalence of depressive symptoms and anxiety among different groups of glucose metabolism in…

  10. Prevalence of disturbed eating behavior and associated symptoms of anxiety and depression among adult males and females with type 1 diabetes.

    Journal of eating disorders2018n=28230 influential citations

    <h4>Background</h4>The increased prevalence of disturbed eating behaviors (DEB), depression, and anxiety in type 1 diabetes (T1D) is generally well established; however the majority of existing research to date has focused on female…

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