Microbiome TestsEvidence & Dosage

Top studies on Microbiome Tests

Ranked by influential-citation count and publication year.

1. 01

   Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach.

   Gut·2006·n=12200 influential citations

   <h4>Background and aim</h4>A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with…

2. 02

   Gut microbiome development along the colorectal adenoma-carcinoma sequence.

   Nature communications·2015200 influential citations

   Colorectal cancer, a commonly diagnosed cancer in the elderly, often develops slowly from benign polyps called adenoma. The gut microbiota is believed to be directly involved in colorectal carcinogenesis. The identity and functional…

3. 03

   Low counts of Faecalibacterium prausnitzii in colitis microbiota.

   Inflammatory bowel diseases·2009200 influential citations

   <h4>Background</h4>The intestinal microbiota is suspected to play a role in colitis and particularly in inflammatory bowel disease (IBD) pathogenesis. The aim was to compare the fecal microbiota composition of patients with colitis to that…

4. 04

   Defining the healthy "core microbiome" of oral microbial communities.

   BMC microbiology·2009·n=100200 influential citations

   <h4>Background</h4>Most studies examining the commensal human oral microbiome are focused on disease or are limited in methodology. In order to diagnose and treat diseases at an early and reversible stage an in-depth definition of health…

5. 05

   Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives.

   Gut·2011·n=68200 influential citations

   <h4>Background and aims</h4>A general dysbiosis of the intestinal microbiota has been established in patients with Crohn's disease (CD), but a systematic characterisation of this dysbiosis is lacking. Therefore the composition of the…

6. 06

   A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes.

   Gastroenterology·2010200 influential citations

   <h4>Background & aims</h4>The composition of the gastrointestinal microbiota is thought to have an important role in the etiology of inflammatory bowel diseases (IBDs) such as Crohn's disease (CD) and ulcerative colitis (UC).…

7. 07

   Symbiotic gut microbes modulate human metabolic phenotypes.

   Proceedings of the National Academy of Sciences of the United States of America·2008200 influential citations

   Humans have evolved intimate symbiotic relationships with a consortium of gut microbes (microbiome) and individual variations in the microbiome influence host health, may be implicated in disease etiology, and affect drug metabolism,…

8. 08

   Pyrosequencing study of fecal microflora of autistic and control children.

   Anaerobe·2010·n=33200 influential citations

   There is evidence of genetic predisposition to autism, but the percent of autistic subjects with this background is unknown. It is clear that other factors, such as environmental influences, may play a role in this disease. In the present…

9. 09

   Comparative analysis of human gut microbiota by barcoded pyrosequencing.

   PloS one·2008·n=6199 influential citations

   Humans host complex microbial communities believed to contribute to health maintenance and, when in imbalance, to the development of diseases. Determining the microbial composition in patients and healthy controls may thus provide novel…

10. 10

    The core gut microbiome, energy balance and obesity.

    The Journal of physiology·2009195 influential citations

    Metagenomics is an emerging field focused on characterizing the structures, functions and dynamic operations of microbial communities sampled in their native habitats without the need for culture. Here, we present findings from a 16S rRNA…