Saffron (Crocin)Studienlage & Dosis

Top-Studien zu Saffron (Crocin)

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

1. 01

   Protective role of antioxidant supplementation for depression and anxiety: A meta-analysis of randomized clinical trials.

   J Affect Disord·2023·n=52Meta-Analysis99 einflussreiche Zitationen

   <h4>Background</h4>New research supports an integrated approach to treating depression, and lifestyle modifications should be a regular component of both preventative and treatment programs. Therefore, in order to investigate the…

   Befund: The subgroup analyses by scale type and country remained significant for the positive effects on depressive and anxiety states.

2. 02

   Effect of saffron supplementation on oxidative stress markers (MDA, TAC, TOS, GPx, SOD, and pro-oxidant/antioxidant balance): An updated systematic review and meta-analysis of randomized placebo-controlled trials.

   Front Med (Lausanne)·2023·n=934Systematic Review71 einflussreiche Zitationen

   Introduction This study aimed to perform an updated systematic review and meta-analysis to evaluate the effectiveness of saffron supplementation on oxidative stress markers [malondialdehyde (MDA), total antioxidant capacity (TAC), total…

3. 03

   Saffron: The Golden Spice with Therapeutic Properties on Digestive Diseases.

   Nutrients·2019Systematic Review64 einflussreiche Zitationen

   Saffron is a natural compound that has been used for centuries in many parts of the world as a food colorant and additive. It was shown to have the ability to mitigate various disorders through its known anti-inflammatory and anti-oxidant…

4. 04

   Saffron (Crocus sativus) for depression: a systematic review of clinical studies and examination of underlying antidepressant mechanisms of action.

   Hum Psychopharmacol·2014·n=6Systematic Review58 einflussreiche Zitationen

   <h4>Background</h4>Saffron, a spice derived from the flower of Crocus sativus, has now undergone several trials examining its antidepressant effects and, in a recent meta-analysis, was confirmed to be effective for the treatment of major…

5. 05

   Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials.

   Nutr Rev·2025·n=8meta58 einflussreiche Zitationen

   CONTEXT: Saffron, a natural remedy with potential antidepressant and anxiolytic properties, has gained attention as a potential therapeutic option. OBJECTIVE: This systematic review and meta-analysis aimed to evaluate the comparative…

   Befund: The authors conclude that saffron could be a potential SSRI alternative to reduce depressive and anxiety symptoms with fewer adverse events.

6. 06

   Effects of Crocin on Diabetic Maculopathy: A Placebo-Controlled Randomized Clinical Trial.

   Am J Ophthalmol·2018·n=101RCT53 einflussreiche Zitationen

   <h4>Objective</h4>Diabetic macular edema (DME) is one of the most important sight-threatening complications in patients with diabetes. Owing to neuroprotective properties, crocin, as the main constituent in saffron, is thought to be useful…

7. 07

   Effect of crocin of Crocus sativus L. on serum inflammatory markers (IL-6 and TNF-α) in chronic obstructive pulmonary disease patients: a randomised, double-blind, placebo-controlled trial.

   Br J Nutr·2023·n=57RCT51 einflussreiche Zitationen

   Different factors, such as inflammation, oxidative stress, extracellular matrix degradation and apoptosis, affect the pathophysiology of chronic obstructive pulmonary disease (COPD), as a progressive disease characterised by permanent…

8. 08

   Crocin ameliorates neuroinflammation and cognitive impairment in mice with Alzheimer's disease by activating PI3K/AKT pathway.

   Brain and behavior·2024·n=68E50 einflussreiche Zitationen

   Crocin has a good prospect in the treatment of Alzheimer's disease (AD), but the mechanisms underlying its neuroprotective effects remain elusive. This study aimed to investigate the neuroprotective effects of Crocin and its underlying…

9. 09

   Saffron (Crocus sativus L.) and major depressive disorder: a meta-analysis of randomized clinical trials.

   J Integr Med·2013·n=2Meta-Analysis49 einflussreiche Zitationen

   <h4>Background</h4>Due to safety concerns and side effects of many antidepressant medications, herbal psychopharmacology research has increased, and herbal remedies are becoming increasingly popular as alternatives to prescribed…

   Befund: Saffron supplementation significantly reduced depressive symptoms compared with placebo in adults with major depressive disorder.

10. 10

    A systematic review of the potential herbal sources of future drugs effective in oxidant-related diseases.

    Inflamm Allergy Drug Targets·2009·n=46Systematic Review46 einflussreiche Zitationen

    <h4>Objective</h4>This review focuses on the medicinal plants growing and having history of folk medicine in Iran and found effective as anti free radical damage in animal or human.<h4>Design</h4>Embase, Scopus, Pubmed, Web of Science,…

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