SARMsEvidence & Dosage
Selective androgen receptor modulators — doping, off-label, liver risk.
Evidence at a glance
- Total studies
- 122
- With abstract
- 49
- Meta / Systematic / RCT
- 1
- Highly cited
- 47
- Publication years
- 1999–2026
SARMs in the context of Performance
This topic is part of our "Performance" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to PerformanceTop studies on SARMs
Ranked by influential-citation count and publication year.
The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice.
Current clinical pharmacology2013n=1095 influential citationsSelective estrogen receptor modulators (SERMs) are structurally different compounds that interact with intracellular estrogen receptors in target organs as estrogen receptor agonists or antagonists. These drugs have been intensively…
Development of selective androgen receptor modulators (SARMs).
Molecular and cellular endocrinology201875 influential citationsThe Androgen Receptor (AR), a member of the steroid hormone receptor family, plays important roles in the physiology and pathology of diverse tissues. AR ligands, which include circulating testosterone and locally synthesized…
Efficacy and safety of Resmetirom, a selective thyroid hormone receptor-β agonist, in the treatment of metabolic dysfunction-associated steatotic liver disease (MASLD): a systematic review and meta-analysis.
Scientific reports2024n=2,35972 influential citationsMetabolic dysfunction-associated steatotic liver disease (MASLD) is an important public health problem owing to its high prevalence and associated morbidity and mortality secondary to progressive liver disease and cardiovascular events.…
Selective Androgen Receptor Modulators (SARMs) Effects on Physical Performance: A Systematic Review of Randomized Control Trials.
Clinical endocrinology2025n=97071 influential citations<h4>Objective</h4>Selective androgen receptor modulators (SARMs) are potential treatments for ameliorating age-related physical dysfunctions caused by sarcopenia, cachexia and chronic illnesses such as cancer. The purpose of this…
Fake anabolic androgenic steroids on the black market - a systematic review and meta-analysis on qualitative and quantitative analytical results found within the literature.
BMC public health2022n=1865 influential citationsObjective Supraphysiologic doses of anabolic androgenic steroids (AAS) are widely used to improve body image and sport performance goals. These substances can easily be acquired over the internet, leading to a substantial black market. We…
Selective androgen receptor modulator use and related adverse events including drug-induced liver injury: Analysis of suspected cases.
2024n=2,26965 influential citations<h4>Purpose</h4>Selective androgen receptor modulators (SARMs) have demonstrated agonist activity on the androgen receptor in various tissues, stimulating muscle mass growth and improving bone reconstruction. Despite being in clinical…
Systematic Review of Safety of Selective Androgen Receptor Modulators in Healthy Adults: Implications for Recreational Users.
Journal of xenobiotics2023n=2,13655 influential citationsSelective Androgen Receptor Modulators (SARMs) are not FDA approved, and obtaining SARMs for personal use is illegal. Nevertheless, SARM use is increasingly popular amongst recreational athletes. Recent case reports of drug-induced liver…
Polypharmacy among anabolic-androgenic steroid users: a descriptive metasynthesis.
Substance abuse treatment, prevention, and policy2015n=2254 influential citations<h4>Background</h4>As far as we are aware, no previous systematic review and synthesis of the qualitative/descriptive literature on polypharmacy in anabolic-androgenic steroid(s) (AAS) users has been published.<h4>Method</h4>We…
Selective androgen receptor modulators: the future of androgen therapy?
Translational andrology and urology202053 influential citationsSelective androgen receptor modulators (SARMs) are small molecule drugs that function as either androgen receptor (AR) agonists or antagonists. Variability in AR regulatory proteins in target tissues permits SARMs to selectively elicit…
Selective androgen receptor modulators as function promoting therapies.
Current opinion in clinical nutrition and metabolic care200946 influential citations<h4>Purpose of review</h4>The past decade has witnessed an unprecedented discovery effort to develop selective androgen receptor modulators (SARMs) that improve physical function and bone health without adversely affecting the prostate and…
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