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StressEvidence & Dosage

Acute vs. chronic stress response, allostasis, coping strategies.

Evidence at a glance

Total studies
366
With abstract
33
Meta / Systematic / RCT
0
Highly cited
2
Publication years
2004–2026

Stress in the context of Mental

This topic is part of our "Mental" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

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Top studies on Stress

Ranked by influential-citation count and publication year.

  1. Effects of psychological stress on autonomic control of heart in rats.

    Exp Anim2004Study11 influential citations

    The aim of this study was to examine the effects of psychological stress on autonomic control of the heart in rats. For this purpose, we evoked anxiety-like or fear-like states in rats by means of classical conditioning and examined…

  2. Dietary dimethylglycine alleviates cyclic heat stress-induced jejunal injury in yellow-feathered broilers by inhibiting the TLR4/NF-κB signaling pathway and restoring MUC2 expression.

    Poultry science2026

    This study aimed to investigate the protective effect and mechanism of dietary dimethylglycine (DMG) on jejunal injury in yellow-feathered broilers subjected to cyclic heat stress (HS). A total of 180 35-day-old male yellow-feathered…

  3. Kaempferol Attenuates Myocardial Ischemia-Reperfusion Injury by Suppressing Ferroptosis via the KEAP1-Nrf2-GPX4 Axis.

    The Kaohsiung journal of medical sciences2026E

    Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated…

  4. Early life stress exposure alters brain vasculature transcriptomic profiles in areas regulating stress resilience

    bioRxiv2026

    Early life stress (ELS) events during sensitive postnatal time periods can recalibrate future stress responsiveness and precipitate mental disorders. Neurovascular adaptations can influence cognition, mood, and stress responses. Disruption…

  5. Hypoxia and Oxidation Pathway Crosstalk in Head and Neck Squamous Cell Carcinoma.

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery2026

    Objective Treatment resistance remains a significant challenge in head and neck squamous cell carcinoma (HNSCC). Alterations in oxidative stress and hypoxia pathways predict poor therapeutic outcomes. The nuclear factor erythroid 2‐related…

  6. Epigallocatechin gallate attenuates free fatty acid-induced hepatocyte apoptosis by restoring endoplasmic reticulum homeostasis.

    Veterinary research communications2026

    Dairy cows during the transition period frequently experience negative energy balance (NEB), leading to elevated circulating non-esterified fatty acids (NEFA), which is a major risk factor for fatty liver disease. This study aimed to…

  7. Netrin-1 protects against doxorubicin-induced cardiotoxicity by suppressing ferroptosis via the UNC5B-LKB1/CaMKKβ-AMPK-NRF2 axis.

    Molecular and cellular biochemistry2026

    Doxorubicin (DOX)-induced cardiotoxicity is strongly associated with ferroptosis and oxidative stress, yet the endogenous protective mechanisms remain incompletely understood. This study aimed to determine whether Netrin-1 protects against…

  8. PagE2Fa1 negatively regulates drought tolerance in poplar by modulating root development and stomatal aperture.

    Tree physiology2026

    E2F/DP proteins play a critical role in plant growth by regulating the cell cycle, yet the function of E2F/DP proteins in stress responses of woody plants is poorly understood. Here, nine PagE2F/DP members were identified in 84K poplar…

  9. Isorhamnetin inhibits migration and promotes apoptosis via modulation of oxidative stress, mitochondrial dysfunction, and the TIGIT/CD155 axis in 4T1 breast cancer cells.

    Frontiers in cell and developmental biology2026

    Background Isorhamnetin (ISO), a natural flavonoid derived from traditional Chinese medicine, has demonstrated potential antitumor activity. This study aimed to investigate the effects of ISO on the proliferation, migration, and apoptosis…

  10. Galectin-3 Promotes Graft Injury via NLRP3 Pyroptosis in Steatotic Liver Transplantation: A Therapeutic Target for Donor Optimization.

    Journal of clinical and translational hepatology2026

    <h4>Background and aims</h4>Steatotic donor livers are highly susceptible to post-transplant dysfunction; however, the underlying mechanisms remain incompletely understood. This study aimed to investigate the role of galectin-3…

Frequently asked

What dosage was studied?
• Psychological stress induction via classical conditioning (not reported)
Which population does the evidence apply to?
Most studies investigated: animal.
Are there safety considerations for Stress?
• not reported

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