NeurotransmittersEvidence & Dosage

Top studies on Neurotransmitters

Ranked by influential-citation count and publication year.

1. 01

   Efficacy of non-invasive brain stimulation combined with antidepressant medications for depression: a systematic review and meta-analysis of randomized controlled trials.

   Syst Rev·2024·n=135Meta-Analysis67 influential citations

   <h4>Background</h4>Antidepressants, noninvasive brain stimulation (NIBS), and their combination are commonly used in routine clinical practice. Nevertheless, there is a continuous dispute regarding whether the effectiveness of NIBS in…

   Finding: In this meta-analysis of 18 randomized controlled trials, combination treatment with non-invasive brain stimulation and antidepressants was significantly more effective than antidepressant monotherapy for improving depressive symptoms.

2. 02

   Effects of exercise training on inflammatory, neurotrophic and immunological markers and neurotransmitters in people with depression: A systematic review and meta-analysis.

   Journal of affective disorders·2023·n=75761 influential citations

   <h4>Background</h4>Major depressive disorder is the most common type of mental disorder. The biological pathway by which exercise promotes its antidepressant effects remains uncleared. This study aimed to systematically review the chronic…

3. 03

   Pirfenidone regulates seizures through the HMGB1/TLR4 axis to improve cognitive functions and modulate oxidative stress and neurotransmitters in PTZ-induced kindling in mice

   Frontiers in Pharmacology·202560 influential citations

   <h4>Background</h4>Epilepsy is a neurological disorder characterized by recurrent seizures due to abnormal electrical activity in the brain. Pirfenidone, an antifibrotic drug, has shown anti-inflammatory and antioxidant properties in…

4. 04

   Generalizable and transportable resting-state neural signatures characterized by functional networks, neurotransmitters, and clinical symptoms in autism

   Molecular Psychiatry·202438 influential citations

   Autism spectrum disorder (ASD) is a lifelong condition with elusive biological mechanisms. The complexity of factors, including inter-site and developmental differences, hinders the development of a generalizable neuroimaging classifier…

5. 05

   Neurotransmitters: an emerging target for therapeutic resistance to tumor immune checkpoint inhibitors

   Molecular Cancer·202535 influential citations

   The critical role of neurotransmitters in the resistance to tumor immune checkpoint inhibitor (ICI) is becoming increasingly significant in therapeutic contexts. ICIs work by enhancing antitumor immunity through the blockade of the…

6. 06

   Biomimetic Analysis of Neurotransmitters for Disease Diagnosis through Light‐Driven Nanozyme Sensor Array and Machine Learning

   Advanced Science·202531 influential citations

   Neurological diseases, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis, pose a significant global health challenge due to their complex pathogenesis and widespread prevalence. These disorders are often associated…

7. 07

   6-Shogaol, a neuro-nutraceutical derived from ginger, alleviates motor symptoms and depression-like behaviors and modulates the release of monoamine neurotransmitters in Parkinson's disease mice

   European Journal of Nutrition·202529 influential citations

   <h4>Purpose</h4>Parkinson's disease (PD) disrupts the regulation of neurotransmitters in the brain, causing patients to experience not only motor symptoms but also non-motor symptoms such as depression. 6-shogaol (6S) is a potential…

8. 08

   Interactions Involving Glycine and Other Amino Acid Neurotransmitters: Focus on Transporter-Mediated Regulation of Release and Glycine–Glutamate Crosstalk

   Biomedicines·202428 influential citations

   Glycine plays a pivotal role in the Central Nervous System (CNS), being a major inhibitory neurotransmitter as well as a co-agonist of Glutamate at excitatory NMDA receptors. Interactions involving Glycine and other neurotransmitters are…

9. 09

   Nanomaterial-enhanced fluorescence sensors for dopamine neurotransmitters: a photophysical perspective

   Analytical Methods·202528 influential citations

   Neurotransmitters are critical in regulating mood, motivation, reward, and various bodily functions. These are necessary elements for cognitive and physical processes. In addition, neurotransmitters play a crucial role in the…

10. 10

    Periostracum Cicadae Extract and N-Acetyldopamine Regulate the Sleep-Related Neurotransmitters in PCPA-Induced Insomnia Rats

    Molecules·202427 influential citations

    Insomnia is the second most prevalent mental illness worldwide. Periostracum cicadae (PC), as an animal traditional Chinese medicine with rich pharmacological effects, has been documented as a treatment for children's night cries, and…

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