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Vitamine & Mineralien

MetaanalysenStudienlage & Dosis

Zusammenführung mehrerer Studien — Heterogenität, Publikationsbias.

Studienlage in Zahlen

Studien gesamt
530
Mit Abstract
40
Meta / Systematic / RCT
9
Häufig zitiert
5
Erscheinungsjahre
2001–2026

Metaanalysen im Kontext von Vitamine & Mineralien

Dieses Thema ist Teil unserer Welt „Vitamine & Mineralien". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Vitamine & Mineralien

Top-Studien zu Metaanalysen

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

  1. The effects of foods on LDL cholesterol levels: A systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials.

    Nutr Metab Cardiovasc Dis2021n=37Meta-Analysis75 einflussreiche Zitationen

    AIMS: To systematically evaluate the evidence regarding the effects of foods on LDL cholesterol levels and to compare the findings with current guidelines. DATA SYNTHESIS: From inception through June 2019, we searched PubMed, Cochrane…

    Befund: Unfiltered coffee caused a moderate to large increase in LDL cholesterol.

  2. Heart rate variability in mental disorders: an umbrella review of meta-analyses.

    Transl Psychiatry2025n=21systematic74 einflussreiche Zitationen

    Heart rate variability (HRV) monitoring is increasingly applied in the realm of mental disorders; however, it remains a subject of controversy. This umbrella review summarizes HRV differences between individuals with mental disorders and…

  3. Association of Opioid Agonist Treatment With All-Cause Mortality and Specific Causes of Death Among People With Opioid Dependence: A Systematic Review and Meta-analysis.

    JAMA psychiatry2021n=3.85212 einflussreiche Zitationen

    Importance Mortality among people with opioid dependence is higher than that of the general population. Opioid agonist treatment (OAT) is an effective treatment for opioid dependence; however, there has not yet been a systematic review on…

  4. Intermittent fasting and health outcomes: an umbrella review of systematic reviews and meta-analyses of randomised controlled trials

    EClinicalMedicine2024n=23Study5 einflussreiche Zitationen

    Summary Background Benefits of Intermittent fasting (IF) on health-related outcomes have been found in a range of randomised controlled trials (RCTs). Our umbrella review aimed to systematically analyze and synthesize the available causal…

  5. Interventions for treatment of COVID-19: Second edition of a living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

    medRxiv2020n=40.2495 einflussreiche Zitationen

    Background COVID-19 is a rapidly spreading disease that has caused extensive burden to individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently needed. This is the second edition of a living systematic…

  6. Ivermectin for Prevention and Treatment of COVID-19 Infection: A Systematic Review, Meta-analysis, and Trial Sequential Analysis to Inform Clinical Guidelines

    American Journal of Therapeutics2021n=3.4064 einflussreiche Zitationen

    Background: Repurposed medicines may have a role against the SARS-CoV-2 virus. The antiparasitic ivermectin, with antiviral and anti-inflammatory properties, has now been tested in numerous clinical trials. Areas of uncertainty: We…

  7. A bibliometric study of the top 100 most-cited randomized controlled trials, systematic reviews and meta-analyses published in endodontic journals.

    International Endodontic Journal2019n=704 einflussreiche Zitationen

    Aim To identify and analyse the main features of the top 100 most‐cited randomized controlled trials, systematic reviews and meta‐analyses published in endodontic journals from 1961 to 2018. Methodology The Clarivate Analytics’ Web of…

  8. Dietary Patterns Associated With Anti-inflammatory Effects: An Umbrella Review of Systematic Reviews and Meta-analyses.

    Nutr Rev2026n=30Systematic Review4 einflussreiche Zitationen

    <h4>Context</h4>Noncommunicable diseases significantly impact global health, and chronic inflammation is a common pathological feature of these conditions. The relationship between chronic inflammation and dietary intake is increasingly…

  9. Vaccines to prevent COVID-19: A living systematic review with Trial Sequential Analysis and network meta-analysis of randomized clinical trials

    PLoS ONE2022n=8643 einflussreiche Zitationen

    Background COVID-19 is rapidly spreading causing extensive burdens across the world. Effective vaccines to prevent COVID-19 are urgently needed. Methods and findings Our objective was to assess the effectiveness and safety of COVID-19…

  10. Interventions for treatment of COVID-19: A living systematic review with meta-analyses and trial sequential analyses (The LIVING Project)

    PLoS Medicine2020n=13.3122 einflussreiche Zitationen

    <h4>Background</h4>Coronavirus disease 2019 (COVID-19) is a rapidly spreading disease that has caused extensive burden to individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently needed.<h4>Methods and…

Häufige Fragen

Was sagt die Studienlage zu Metaanalysen?
Unfiltered coffee caused a moderate to large increase in LDL cholesterol.
Welche Dosierung wurde in den Studien untersucht?
• Foods and dietary components affecting LDL cholesterol (e.g. canola oil, plant sterols/stanols, soluble fiber, coffee, soy protein, tomatoes, flaxseeds, almonds, avocados, turmeric, pulses, hazelnuts, walnuts, wholegrains, green tea, sugar) (Not reported) • Various mental disorder treatments (antipsychotics, rTMS, physiotherapy, psychotherapy, pharmacotherapy, mindfulness, virtual reality biofeedback, antidepressants) (Not reported; treatment modalities varied across included meta-analyses) • opioid agonist treatment (OAT)
Für welche Population gilt die Evidenz?
Die meisten Studien untersuchten: unknown; patient.
Gibt es Sicherheitshinweise zu Metaanalysen?
• Not reported • No adverse events were reported in this umbrella review excerpt. • Antipsychotic treatment was associated with decreased HRV in one pooled analysis. • rTMS, physiotherapy, and psychotherapy showed HRV changes in some pooled analyses.

Weitere Themen in Vitamine & Mineralien

Magnesium

Magnesiumformen, Schlaf, Krämpfe, Stress und Dosierung.

Creatine Monohydrate

Kraft, Muskelaufbau, Kognition und Sicherheit von Kreatin.

Ashwagandha

Stress, Schlaf, Cortisol und mögliche Nebenwirkungen.

Melatonin-Optimierung

Melatonin-Bedarf, Dosierung (0,3–5 mg), retardierte Formen, Circadian-Rhythmus und Sicherheit bei Langzeitanwendung.

Caffeine + L-Theanine

Koffein, L-Theanin, Fokus, Wachheit und Verträglichkeit.

NAD+ Precursors

NMN, NR, NAD+, Alterungsbiologie und Evidenzlage.

Omega-3-Fettsäuren

EPA, DHA, ALA — Bedarf, Quellen (Fisch, Algen), Omega-3-Index als Biomarker und kardiovaskuläre RCT-Daten.

Vitamin-Optimierung

Strategien für die Vitamin-Optimierung: Bedarfsermittlung, Bioverfügbarkeit, Synergien und Sicherheits-Obergrenzen der wichtigsten Mikronährstoffe.

Melatonin-Signalwege

Melatonin als Multi-System-Hormon: antioxidative, immunmodulatorische, mitochondriale und neuroprotektive Wirkungen jenseits des Schlafs.

Tierstudien vs. Humanstudien

Maus ≠ Mensch — Übersetzbarkeit von Resveratrol bis Rapamycin kritisch.

Bias

Sponsoring, Selection Bias, Confirmation Bias, Industriefinanzierung.

Herz-Kreislauf-System

Blutdruck, Herzfrequenz, Endothel, Cholesterin, kardiovaskuläre Risikofaktoren.

Kontraindikationen

Wann etwas NICHT genommen werden darf: Schwangerschaft, Vorerkrankungen.

Coenzym Q10 (CoQ10 / Ubiquinol)

Mitochondrien, Statine, Energie und kardiovaskuläre Outcomes.

Korrelation vs. Kausalität

Klassische Fehlinterpretation populärer Gesundheitsstudien.

Curcumin

Entzündung, Bioverfügbarkeit (Piperin), Kurkuma-Extrakte und klinische Outcomes.

Verdauungssystem

Magensäure, Enzyme, Resorption, Darm-Hirn-Achse, Mikrobiom.

Effektstärke

p-Wert vs. praktische Relevanz, Cohen's d, Confidence Intervals.

Ferritin & Eisen

Ferritin, Transferrinsättigung, Eisenmangel vs. Eisenüberladung.

Glutathione

Master-Antioxidans, liposomale vs. NAC-Formen und Detoxifikation.

Verwandte Themen aus anderen Welten

Methoden

Lärm

Chronischer Lärm — Stress, Schlafqualität, Hörverlust.

Methoden

Beziehungen

Stärkster Longevity-Prädiktor — Qualität > Quantität.

Methoden

Schlafhygiene

Lichtmanagement, Temperatur, Konsistenz und Schlafarchitektur-Optimierung.

Methoden

VOCs

Möbel, Reinigungsmittel, Lacke — chronische niedrige Exposition.

Longevity

Caloric Restriction

CR-Mimetika, Lebensspannen-Forschung und NHP-Studien.

Longevity

Epigenetik

DNA-Methylierung, Histon-Modifikationen, Umwelteinflüsse auf Genexpression.