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Vitamine & Mineralien

GlutathioneStudienlage & Dosis

Master-Antioxidans, liposomale vs. NAC-Formen und Detoxifikation.

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705
Mit Abstract
50
Meta / Systematic / RCT
126
Häufig zitiert
50
Erscheinungsjahre
2000–2026

Glutathione im Kontext von Vitamine & Mineralien

Dieses Thema ist Teil unserer Welt „Vitamine & Mineralien". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Vitamine & Mineralien

Top-Studien zu Glutathione

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

  1. Redox-manipulating nanocarriers for anticancer drug delivery: a systematic review.

    J Nanobiotechnology2024Systematic Review171 einflussreiche Zitationen

    Spatiotemporally controlled cargo release is a key advantage of nanocarriers in anti-tumor therapy. Various external or internal stimuli-responsive nanomedicines have been reported for their ability to increase drug levels at the diseased…

  2. Oxidative stress-related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: A systematic review and meta-analysis.

    J Clin Periodontol2019n=2.972Meta-Analysis119 einflussreiche Zitationen

    Aim Oxidative stress ( OS ) biomarkers have been detected in saliva and gingival crevicular fluid ( GCF ) during chronic periodontitis ( CP ) progression; however, the relationship between OS biomarkers and CP progression remains elusive.…

    Befund: Chronic periodontitis was associated with significant increases in salivary malondialdehyde, nitric oxide, total oxidant status, and 8-hydroxy-deoxyguanosine levels.

  3. Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis.

    Neurobiol Dis2013Meta-Analysis102 einflussreiche Zitationen

    Abnormal oxidative stress is an established feature of Alzheimer's disease, but clinical trials aiming to reduce oxidative stress have not yet proven an effective therapy for dementia patients. The purpose of this review is to…

    Befund: In this meta-analysis, markers of lipid peroxidation were elevated in blood in both Alzheimer's disease and mild cognitive impairment.

  4. Oxidative stress marker aberrations in children with autism spectrum disorder: a systematic review and meta-analysis of 87 studies (N = 9109).

    Transl Psychiatry2021n=910Meta-Analysis102 einflussreiche Zitationen

    There is increasing awareness that oxidative stress may be implicated in the pathophysiology of autism spectrum disorder (ASD). Here we aimed to investigate blood oxidative stress marker profile in ASD children by a meta-analysis. Two…

    Befund: In this meta-analysis of 87 studies, children with ASD had higher blood concentrations of GSSG, malondialdehyde, homocysteine, S-adenosylhomocysteine, nitric oxide, and copper than healthy control children.

  5. Sleep deprivation and oxidative stress in animal models: a systematic review.

    Oxid Med Cell Longev2015n=44Meta-Analysis98 einflussreiche Zitationen

    Because the function and mechanisms of sleep are partially clear, here we applied a meta-analysis to address the issue whether sleep function includes antioxidative properties in mice and rats. Given the expansion of the knowledge in the…

  6. Oxidative stress-related biomarkers in autism: systematic review and meta-analyses.

    Free Radic Biol Med2012Meta-Analysis95 einflussreiche Zitationen

    Autism spectrum disorders (ASDs) are rarely diagnosed in children younger than 2 years, because diagnosis is based entirely on behavioral tests. Oxidative damage may play a central role in this pathogenesis, together with the…

  7. Oxidative stress and frailty: A systematic review and synthesis of the best evidence.

    Maturitas2017n=6.349Systematic Review93 einflussreiche Zitationen

    <h4>Objective</h4>Oxidative stress (OS) is associated with accelerated aging. Previous studies have suggested a possible relationship between OS and frailty but this association remains unclear. We conducted a systematic review to…

  8. Omega-3 fatty acids supplementation and oxidative stress parameters: A systematic review and meta-analysis of clinical trials.

    Pharmacol Res2019n=2.875Meta-Analysis87 einflussreiche Zitationen

    Omega-3 fatty acids (omega-3 FAs) supplementation effects on oxidants and antioxidants are always controversial. Oxidative stress (OS) is one of the major mechanisms that contribute to the pathogenesis of several chronic diseases. The…

  9. Biomarker responses in fish exposed to polycyclic aromatic hydrocarbons (PAHs): Systematic review and meta-analysis.

    Environ Pollut2018Meta-Analysis80 einflussreiche Zitationen

    Biomarkers of antioxidant and biotransformation systems are commonly used to assess polycyclic aromatic hydrocarbons (PAHs) pollution in fish. Despite their extensive application of biomarkers, contradictory results are vastly reported in…

    Befund: PAHs exposure significantly affected biomarker responses in fish.

  10. Altered central and blood glutathione in Alzheimer's disease and mild cognitive impairment: a meta-analysis.

    Alzheimers Res Ther2022Meta-Analysis76 einflussreiche Zitationen

    Background Increasing evidence implicates oxidative stress (OS) in Alzheimer disease (AD) and mild cognitive impairment (MCI). Depletion of the brain antioxidant glutathione (GSH) may be important in OS-mediated neurodegeneration, though…

    Befund: Alzheimer’s disease had lower intracellular and extracellular blood glutathione overall compared with healthy controls.

Häufige Fragen

Welche Dosierung wurde in den Studien untersucht?
• Redox-manipulating nanocarriers / disulfide-based redox-responsive nanocarriers (unclear) • Assessment of local oxidative stress-related biomarkers in saliva and gingival crevicular fluid • Not applicable; systematic review/meta-analysis of blood oxidative stress markers (Not reported)
Gibt es Sicherheitshinweise zu Glutathione?
• No adverse events reported in the abstract. • Not reported. • Not reported • Mechanical sleep deprivation methods were favored to avoid drug-related adverse effects.

Weitere Themen in Vitamine & Mineralien

Magnesium

Magnesiumformen, Schlaf, Krämpfe, Stress und Dosierung.

Creatine Monohydrate

Kraft, Muskelaufbau, Kognition und Sicherheit von Kreatin.

Ashwagandha

Stress, Schlaf, Cortisol und mögliche Nebenwirkungen.

Melatonin-Optimierung

Melatonin-Bedarf, Dosierung (0,3–5 mg), retardierte Formen, Circadian-Rhythmus und Sicherheit bei Langzeitanwendung.

Caffeine + L-Theanine

Koffein, L-Theanin, Fokus, Wachheit und Verträglichkeit.

NAD+ Precursors

NMN, NR, NAD+, Alterungsbiologie und Evidenzlage.

Omega-3-Fettsäuren

EPA, DHA, ALA — Bedarf, Quellen (Fisch, Algen), Omega-3-Index als Biomarker und kardiovaskuläre RCT-Daten.

Vitamin-Optimierung

Strategien für die Vitamin-Optimierung: Bedarfsermittlung, Bioverfügbarkeit, Synergien und Sicherheits-Obergrenzen der wichtigsten Mikronährstoffe.

Melatonin-Signalwege

Melatonin als Multi-System-Hormon: antioxidative, immunmodulatorische, mitochondriale und neuroprotektive Wirkungen jenseits des Schlafs.

Tierstudien vs. Humanstudien

Maus ≠ Mensch — Übersetzbarkeit von Resveratrol bis Rapamycin kritisch.

Bias

Sponsoring, Selection Bias, Confirmation Bias, Industriefinanzierung.

Herz-Kreislauf-System

Blutdruck, Herzfrequenz, Endothel, Cholesterin, kardiovaskuläre Risikofaktoren.

Kontraindikationen

Wann etwas NICHT genommen werden darf: Schwangerschaft, Vorerkrankungen.

Coenzym Q10 (CoQ10 / Ubiquinol)

Mitochondrien, Statine, Energie und kardiovaskuläre Outcomes.

Korrelation vs. Kausalität

Klassische Fehlinterpretation populärer Gesundheitsstudien.

Curcumin

Entzündung, Bioverfügbarkeit (Piperin), Kurkuma-Extrakte und klinische Outcomes.

Verdauungssystem

Magensäure, Enzyme, Resorption, Darm-Hirn-Achse, Mikrobiom.

Effektstärke

p-Wert vs. praktische Relevanz, Cohen's d, Confidence Intervals.

Ferritin & Eisen

Ferritin, Transferrinsättigung, Eisenmangel vs. Eisenüberladung.

Immunsystem

Angeborene vs. adaptive Immunität, Entzündung, Autoimmunität.

Verwandte Themen aus anderen Welten

Diagnostik & Biomarker

Blutbild

Kleines/großes Blutbild, Erythrozyten, Leukozyten, Thrombozyten — Standardpanel.

Diagnostik & Biomarker

HRV-Tracking

Herzratenvariabilität als Resilienz- und Erholungs-Indikator.

Diagnostik & Biomarker

Ruhepuls

Trend-Marker für kardiovaskuläre Fitness und Übertraining.

Hormone

Chronischer Stress

Allostatic Load, immunologische und metabolische Folgen, Interventionen.

Hormone

Endometriose

Chronisch-entzündliche Erkrankung — Diagnose, Optionen, Lifestyle-Faktoren.

Hormone

Hashimoto

Autoimmune Schilddrüsenerkrankung — TPO/TG-AK, Selen, Jod-Vorsicht.