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Mediterranean DietEvidence & Dosage

Olive oil, polyphenols, the PREDIMED study, and longevity outcomes.

Studies last updated

Evidence at a glance

Total studies
1,000
With abstract
47
Meta / Systematic / RCT
153
Highly cited
50
Publication years
1991–2026

Mediterranean Diet in the context of Methods

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Top studies on Mediterranean Diet

Ranked by influential-citation count and publication year.

  1. Mediterranean diet in the management and prevention of obesity.

    Exp Gerontol2023Meta-Analysis200 influential citations

    The current pandemic of obesity represents a major global public health problem, mainly due to its association with chronic non-communicable disabling conditions and with increased mortality. Population aging increases the chances of…

  2. The role of the Mediterranean diet in reducing the risk of cognitive impairement, dementia, and Alzheimer's disease: a meta-analysis.

    Geroscience2025n=23Meta-Analysis200 influential citations

    Age-related cognitive impairment and dementia pose a significant global health, social, and economic challenge. While Alzheimer's disease (AD) has historically been viewed as the leading cause of dementia, recent evidence reveals the…

  3. Mediterranean Diet-Based Interventions to Improve Anthropometric and Obesity Indicators in Children and Adolescents: A Systematic Review with Meta-Analysis of Randomized Controlled Trials.

    Adv Nutr2023n=718Meta-Analysis133 influential citations

    To our knowledge, no systematic review with meta-analysis has separately synthesized the effects of Mediterranean diet-based interventions in children and adolescents in relation to the effects on anthropometric measures. A better…

    Finding: Compared with control groups, Mediterranean diet-based interventions produced a small but significant reduction in body mass index.

  4. European Association for the Study of Obesity Position Statement on Medical Nutrition Therapy for the Management of Overweight and Obesity in Adults Developed in Collaboration with the European Federation of the Associations of Dietitians.

    Obes Facts2023n=56systematic122 influential citations

    INTRODUCTION: Obesity affects nearly 1 in 4 European adults increasing their risk for mortality and physical and psychological morbidity. Obesity is a chronic relapsing disease characterized by abnormal or excessive adiposity with risks to…

  5. Adherence to the Mediterranean diet and its protective effects against colorectal cancer: a meta-analysis of 26 studies with 2,217,404 participants.

    Geroscience2025n=2,217,404Meta-Analysis120 influential citations

    Colorectal cancer (CRC) is a major global health concern and represents a significant public health challenge in Hungary, where it exhibits some of the highest morbidity and mortality rates in the European Union. The Mediterranean diet has…

  6. Mediterranean Diet and Sarcopenia Features in Apparently Healthy Adults over 65 Years: A Systematic Review.

    Nutrients2023n=17,663Systematic Review107 influential citations

    Low muscle mass combined with changes in physical function and muscle quality is defined as sarcopenia. In people > 60 years, sarcopenia reaches 10% and tends to increase with age. Individual nutrients, such as protein, may have a…

  7. The effectiveness of the Mediterranean Diet for primary and secondary prevention of cardiovascular disease: An umbrella review.

    Nutr Diet2025n=238Systematic Review87 influential citations

    <h4>Aims</h4>This study aimed to review meta-analyses of randomised controlled trials that evaluated the effectiveness of the Mediterranean Diet for the primary and secondary prevention of cardiovascular disease.<h4>Methods</h4>Five…

  8. Effect of Dietary Approaches on Glycemic Control in Patients with Type 2 Diabetes: A Systematic Review with Network Meta-Analysis of Randomized Trials.

    Nutrients2023n=480meta75 influential citations

    Background: Dietary patterns play a critical role in diabetes management, while the best dietary pattern for Type 2 diabetes (T2DM) patients is still unclear. The aim of this network meta-analysis was to compare the impacts of various…

  9. Effect of nutrition in Alzheimer's disease: A systematic review.

    Front Neurosci2023n=38Systematic Review72 influential citations

    Background and objective Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by declining cognitive ability. Currently, there are no effective treatments for this condition. However, certain measures, such as…

  10. Effect of the Mediterranean diet on incidence of heart failure in European countries: a systematic review and meta-analysis of cohort studies.

    Eur J Clin Nutr2025n=216,385Meta-Analysis72 influential citations

    <h4>Introduction</h4>Heart failure (HF) is one of the most common cardiovascular disorders, and its prevalence is increased due to age, genetics, and lifestyle factors. Emerging evidence suggests that the Mediterranean Diet (Med Diet) is…

Frequently asked

What dosage was studied?
• Mediterranean diet (Not reported) • Mediterranean diet adherence (Higher adherence to the Mediterranean diet; specific dose not reported) • Mediterranean diet-based interventions promoting adherence to the Mediterranean diet (Not reported)
Which population does the evidence apply to?
Most studies investigated: unknown; patient.
Are there safety considerations for Mediterranean Diet?
• Not reported • No adverse events reported; dietary exposure only. • No adverse events were reported in this review. • No adverse events were reported in the excerpt.

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