Dietary FatsEvidence & Dosage
Saturated vs. unsaturated, omega profiles, avoiding trans fats.
Evidence at a glance
- Total studies
- 1,000
- With abstract
- 42
- Meta / Systematic / RCT
- 2
- Highly cited
- 22
- Publication years
- 1949–2026
Dietary Fats in the context of Methods
This topic is part of our "Methods" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.
Go to MethodsTop studies on Dietary Fats
Ranked by influential-citation count and publication year.
Dietary Polyphenols Promote Growth of the Gut Bacterium Akkermansia muciniphila and Attenuate High-Fat Diet-Induced Metabolic Syndrome.
Diabetes2015n=15200 influential citationsDietary polyphenols protect against metabolic syndrome, despite limited absorption and digestion, raising questions about their mechanism of action. We hypothesized that one mechanism may involve the gut microbiota. To test this…
Substituting dietary saturated for monounsaturated fat impairs insulin sensitivity in healthy men and women: The KANWU Study.
Diabetologia2001196 influential citations<h4>Aims/hypothesis</h4>The amount and quality of fat in the diet could be of importance for development of insulin resistance and related metabolic disorders. Our aim was to determine whether a change in dietary fat quality alone could…
Dietary fat intake and the risk of incident dementia in the Rotterdam Study.
Annals of neurology1997180 influential citationsA high intake of saturated fat and cholesterol and a low intake of polyunsaturated fatty acids have been related to an increased risk of cardiovascular disease. Cardiovascular disease has been associated with dementia. We investigated the…
Low-fat dietary pattern and risk of cardiovascular disease: the Women's Health Initiative Randomized Controlled Dietary Modification Trial.
JAMA2006n=48179 influential citations<h4>Context</h4>Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed.<h4>Objective</h4>To test the hypothesis that a dietary intervention,…
Low-fat dietary pattern and risk of invasive breast cancer: the Women's Health Initiative Randomized Controlled Dietary Modification Trial.
JAMA2006n=29,294137 influential citations<h4>Context</h4>The hypothesis that a low-fat dietary pattern can reduce breast cancer risk has existed for decades but has never been tested in a controlled intervention trial.<h4>Objective</h4>To assess the effects of undertaking a…
Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study.
Journal of the National Cancer Institute2006n=2,437135 influential citations<h4>Background</h4>Preclinical and observational studies suggest a relationship between dietary fat intake and breast cancer, but the association remains controversial. We carried out a randomized, prospective, multicenter clinical trial…
Dietary fat intakes for pregnant and lactating women.
The British journal of nutrition200795 influential citationsDietary fat intake in pregnancy and lactation affects pregnancy outcomes and child growth, development and health. The European Commission charged the research project PERILIP, jointly with the Early Nutrition Programming Project, to…
Dietary fats and the risk of incident Alzheimer disease.
Archives of neurology2003n=13185 influential citations<h4>Background</h4>Few studies have investigated the effects of dietary fats on the development of Alzheimer disease. We examined the associations between intake of specific types of fat and incident Alzheimer disease in a biracial…
Are imprecise methods obscuring a relation between fat and breast cancer?
Lancet (London, England)2003n=13,07084 influential citationsPooled analyses of cohort studies show no relation between fat intake and breast-cancer risk. However, food-frequency questionnaire (FFQ) methods used in these studies are prone to measurement error. We assessed diet with an FFQ and a…
Low-fat dietary pattern and weight change over 7 years: the Women's Health Initiative Dietary Modification Trial.
JAMA200683 influential citations<h4>Context</h4>Obesity in the United States has increased dramatically during the past several decades. There is debate about optimum calorie balance for prevention of weight gain, and proponents of some low-carbohydrate diet regimens…
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