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AlcoholEvidence & Dosage

No safe dose per recent evidence — sleep, hormones, cancer risk.

Evidence at a glance

Total studies
1,000
With abstract
50
Meta / Systematic / RCT
36
Highly cited
50
Publication years
1952–2026

Alcohol in the context of Methods

This topic is part of our "Methods" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

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Top studies on Alcohol

Ranked by influential-citation count and publication year.

  1. Prevalence and co-occurrence of substance use disorders and independent mood and anxiety disorders: results from the National Epidemiologic Survey on Alcohol and Related Conditions.

    Archives of general psychiatry2004200 influential citations

    <h4>Background</h4>Uncertainties exist about the prevalence and comorbidity of substance use disorders and independent mood and anxiety disorders.<h4>Objective</h4>To present nationally representative data on the prevalence and comorbidity…

  2. Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence.

    The Cochrane database of systematic reviews2014n=5,430200 influential citations

    <h4>Background</h4>Buprenorphine maintenance treatment has been evaluated in randomised controlled trials against placebo medication, and separately as an alternative to methadone for management of opioid dependence.<h4>Objectives</h4>To…

  3. Nicotine dependence and psychiatric disorders in the United States: results from the national epidemiologic survey on alcohol and related conditions.

    Archives of general psychiatry2004n=43200 influential citations

    <h4>Background</h4>No information is available on the co-occurrence of DSM-IV nicotine dependence and Axis I and II psychiatric disorders in the US population.<h4>Objectives</h4>To present national data on the co-occurrence of current…

  4. A meta-analysis of alcohol consumption and the risk of 15 diseases.

    Preventive medicine2004n=116200 influential citations

    <h4>Background</h4>To compare the strength of evidence provided by the epidemiological literature on the association between alcohol consumption and the risk of 14 major alcohol-related neoplasms and non-neoplastic diseases, plus…

  5. The Alcohol Use Disorders Identification Test (AUDIT): a review of recent research.

    Alcoholism, clinical and experimental research2002200 influential citations

    <h4>Background</h4>Efficient, inexpensive screening for early stage alcohol problems is important in health care settings. The Alcohol Use Disorders Identification Test (AUDIT) has been studied extensively to establish its value in this…

  6. Pharmacotherapy for adults with alcohol use disorders in outpatient settings: a systematic review and meta-analysis.

    JAMA2014n=22,803Meta-Analysis200 influential citations

    <h4>Importance</h4>Alcohol use disorders cause substantial morbidity and early mortality yet remain greatly undertreated. Medications are considerably underused.<h4>Objective</h4>To conduct a systematic review and meta-analysis of the…

  7. Estimation of national, regional, and global prevalence of alcohol use during pregnancy and fetal alcohol syndrome: a systematic review and meta-analysis.

    The Lancet. Global health2017n=67200 influential citations

    <h4>Background</h4>Alcohol use during pregnancy is the direct cause of fetal alcohol syndrome (FAS). We aimed to estimate the prevalence of alcohol use during pregnancy and FAS in the general population and, by linking these two…

  8. Gender Differences in the Epidemiology of Alcohol Use and Related Harms in the United States.

    Alcohol research : current reviews2020n=31,000200 influential citations

    Over the past century, differences in alcohol use and related harms between males and females in the United States have diminished considerably. In general, males still consume more alcohol and experience and cause more alcohol-related…

  9. Global Prevalence of Fetal Alcohol Spectrum Disorder Among Children and Youth: A Systematic Review and Meta-analysis.

    JAMA pediatrics2017200 influential citations

    <h4>Importance</h4>Prevalence estimates are essential to effectively prioritize, plan, and deliver health care to high-needs populations such as children and youth with fetal alcohol spectrum disorder (FASD). However, most countries do not…

  10. Pharmacotherapy for Alcohol Use Disorder: A Systematic Review and Meta-Analysis.

    JAMA2023n=976Meta-Analysis200 influential citations

    Importance Alcohol use disorder affects more than 28.3 million people in the United States and is associated with increased rates of morbidity and mortality. Objective To compare efficacy and comparative efficacy of therapies for alcohol…

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Deliberate tech use, screen time, notification hygiene.

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