Vitamine & Mineralien

Leber & EntgiftungStudienlage & Dosis

Phase-I/II-Entgiftung, Glutathion, Alkohol, „Detox"-Mythen kritisch betrachtet.

Studienlage in Zahlen

Studien gesamt: 907
Mit Abstract: 46
Meta / Systematic / RCT: 0
Häufig zitiert: 3
Erscheinungsjahre: 1981–2026

Leber & Entgiftung im Kontext von Vitamine & Mineralien

Dieses Thema ist Teil unserer Welt „Vitamine & Mineralien". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Vitamine & Mineralien

Top-Studien zu Leber & Entgiftung

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Targeted Down Regulation Of Core Mitochondrial Genes During SARS-CoV-2 Infection
bioRxiv2022n=1925 einflussreiche Zitationen
Defects in mitochondrial oxidative phosphorylation (OXPHOS) have been reported in COVID-19 patients, but the timing and organs affected vary among reports. Here, we reveal the dynamics of COVID-19 through transcription profiles in…
Characteristics, Occurrence, Detection and Detoxification of Aflatoxins in Foods and Feeds
Foods20206 einflussreiche Zitationen
Mycotoxin contamination continues to be a food safety concern globally, with the most toxic being aflatoxins. On-farm aflatoxins, during food transit or storage, directly or indirectly result in the contamination of foods, which affects…
Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival
bioRxiv20234 einflussreiche Zitationen
Under chronic stress, cells must balance competing demands between cellular survival and tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD/NASH), hepatocytes cooperate with structural and…
Role of the CLOCK protein in liver detoxification
British Journal of Pharmacology20193 einflussreiche Zitationen
Background and Purpose Whether and how circadian clock proteins regulate drug detoxification are not known. Here, we have assessed the effects of CLOCK (a core circadian clock protein) on drug metabolism and detoxification. Experimental…
Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes
bioRxiv20233 einflussreiche Zitationen
In all eukaryotic cell types, the unfolded protein response (UPR) upregulates factors that promote protein folding and misfolded protein clearance to help alleviate endoplasmic reticulum (ER) stress. Yet ER stress in the liver is uniquely…
CYP-mediated metabolic divergence underpins oxoglaucine selectivity: Detoxification in healthy hepatocytes versus mitochondrial apoptosis in hepatocellular carcinoma.
Toxicology in vitro : an international journal published in association with BIBRA20262 einflussreiche Zitationen
Oxoglaucine (OXO), an aporphine alkaloid derived from Corydalis yanhusuo, exhibits a broad spectrum of pharmacological activities, including antiviral, antifungal, antiplatelet, and anti-hepatic fibrosis effects, with particularly…
Glutathione supports lipid abundance in vivo
bioRxiv20232 einflussreiche Zitationen
SUMMARY Cells rely on antioxidants to survive. The most abundant antioxidant is glutathione (GSH). The synthesis of GSH is non-redundantly controlled by the glutamate-cysteine ligase catalytic subunit (GCLC). GSH imbalance is implicated in…
Aflatoxin B1 in poultry liver: Toxic mechanism.
Toxicon20231 einflussreiche Zitationen
Aflatoxin B1 (AFB1) is the most common carcinogenic toxin in livestock and poultry feed, seriously endangering poultry production and public health. Liver is the most important organ for the metabolism of exogenous and endogenous…
A single-nucleus transcriptomic atlas of primate liver aging uncovers the pro-senescence role of SREBP2 in hepatocytes
Protein & Cell20231 einflussreiche Zitationen
Aging increases the risk of liver diseases and systemic susceptibility to aging-related diseases. However, cell type-specific changes and the underlying mechanism of liver aging in higher vertebrates remain incompletely characterized.…
Research Progress on the Protection and Detoxification of Phytochemicals against Aflatoxin B1-Induced Liver Toxicity.
Toxicon20211 einflussreiche Zitationen
Aflatoxin B1 (AFB1) is a potent hepatotoxic toxin, which can cause hepatitis, cirrhosis, and liver immunological damage. It has been involved in the etiology of human hepatocellular carcinoma. AFB1 can…