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Whey / Casein ProteinEvidence & Dosage

Amino acid profile, timing, and cow milk tolerance.

Studies last updated

Evidence at a glance

Total studies
826
With abstract
48
Meta / Systematic / RCT
102
Highly cited
50
Publication years
1992–2026

Whey / Casein Protein in the context of Performance

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Top studies on Whey / Casein Protein

Ranked by influential-citation count and publication year.

  1. Effects of Whey Protein, Leucine, and Vitamin D Supplementation in Patients with Sarcopenia: A Systematic Review and Meta-Analysis.

    Nutrients2023n=637meta145 influential citations

    (1) Background: In this study, a meta-analysis was performed to investigate the effects of whey protein, leucine, and vitamin D in sarcopenia; (2) Methods: We searched PubMed, Cochrane Library, Embase, and Scopus databases and retrieved…

  2. Improving sarcopenia in older adults: a systematic review and meta-analysis of randomized controlled trials of whey protein supplementation with or without resistance training.

    J Nutr Health Aging2024n=115Meta-Analysis130 influential citations

    <h4>Objectives</h4>The aim of the study was to comprehensively analyze the effects of whey protein (WP)-enriched supplement intake with or without resistance training (RT) in older patients, either from the community or hospital, who were…

    Finding: In older patients with sarcopenia, whey protein significantly increased appendicular skeletal muscle mass index versus isocaloric placebo or routine consultation.

  3. How processing may affect milk protein digestion and overall physiological outcomes: A systematic review.

    Crit Rev Food Sci Nutr2020n=102Systematic Review113 influential citations

    Dairy is one of the main sources for high quality protein in the human diet. Processing may, however, cause denaturation, aggregation, and chemical modifications of its amino acids, which may impact protein quality. This systematic review…

  4. Innovative applications of whey protein for sustainable dairy industry: Environmental and technological perspectives-A comprehensive review.

    Compr Rev Food Sci Food Saf2024Systematic Review99 influential citations

    Industrial waste management is critical to maintaining environmental sustainability. The dairy industry (DI), as one of the major consumers of freshwater, generates substantial whey dairy effluent, which is notably rich in organic matter…

  5. The Impact of Dairy Protein Intake on Muscle Mass, Muscle Strength, and Physical Performance in Middle-Aged to Older Adults with or without Existing Sarcopenia: A Systematic Review and Meta-Analysis.

    Adv Nutr2019n=142Meta-Analysis92 influential citations

    Sarcopenia is an age-related condition associated with a progressive loss of muscle mass and strength. Insufficient protein intake is a risk factor for sarcopenia. Protein supplementation is suggested to improve muscle anabolism and…

    Finding: The effect of dairy protein on the Short Physical Performance Battery was inconclusive.

  6. Effects of whey and soy protein supplementation on inflammatory cytokines in older adults: a systematic review and meta-analysis.

    Br J Nutr2023n=31Meta-Analysis86 influential citations

    Background and aims: Low-grade inflammation is a mediator of muscle proteostasis. This study aimed to investigate the effects of isolated whey and soy proteins on inflammatory markers. Methods: We conducted a systematic literature search…

  7. Comparative Efficacy of Different Protein Supplements on Muscle Mass, Strength, and Physical Indices of Sarcopenia among Community-Dwelling, Hospitalized or Institutionalized Older Adults Undergoing Resistance Training: A Network Meta-Analysis of Randomized Controlled Trials.

    Nutrients2024n=527Meta-Analysis86 influential citations

    Aging-related sarcopenia exerts harmful impacts on muscle mass, strength, and physical mobility. Protein supplementation has been demonstrated to augment efficacy of resistance training (RT) in elderly. This study compared the relative…

  8. Protein Type, Protein Dose, and Age Modulate Dietary Protein Digestion and Phenylalanine Absorption Kinetics and Plasma Phenylalanine Availability in Humans.

    J Nutr2020n=602Meta-Analysis78 influential citations

    <h4>Background</h4>Dietary protein ingestion stimulates muscle protein synthesis by providing amino acids to the muscle. The magnitude and duration of the postprandial increase in muscle protein synthesis rates are largely determined by…

    Finding: The study concluded that protein type, protein dose, and age modulate dietary protein digestion and amino acid absorption kinetics and subsequent postprandial plasma amino acid availability in humans.

  9. Effects of branched-chain amino acid-rich supplementation on EWGSOP2 criteria for sarcopenia in older adults: a systematic review and meta-analysis.

    Eur J Nutr2022n=35Meta-Analysis62 influential citations

    <h4>Purpose</h4>According to criteria recommended by the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), we analyzed the effects of branched-chain amino acid (BCAA)-rich supplements on muscle strength, muscle mass, and…

    Finding: Essential amino acid supplementation improved handgrip strength more significantly than whey protein supplementation in older people.

  10. Effects of ultrasound on the techno-functional properties of milk proteins: A systematic review.

    Ultrason Sonochem2022Systematic Review60 influential citations

    Techno-functional properties of proteins, including foaming capacity, water holding capacity, solubility, emulsifying properties, and gelling formation, are known to play an important role in food processing technologies and be considered…

Frequently asked

What dosage was studied?
• Whey protein, leucine, and vitamin D supplementation (Varied by trial: e.g., 20.7 g whey protein + 2.8 g leucine + 800 IU vitamin D; 22 g whey protein + 4 g leucine + 100 IU vitamin D; 20 g whey protein + 2.8 g leucine + 800 IU vitamin D) • Whey protein-enriched supplement intake with or without resistance training (Not reported) • Heating/processing-induced milk protein modifications (Not reported)
Are there safety considerations for Whey / Casein Protein?
• No adverse events were reported in the excerpt. • No adverse events were reported in the abstract. • Not reported • Not reported.

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