Peptide

LiraglutidStudienlage & Dosis

Erste GLP-1-Generation für Diabetes/Adipositas — täglich, niedrigere Effektgröße.

Studienlage in Zahlen

Studien gesamt: 816
Mit Abstract: 48
Meta / Systematic / RCT: 4
Häufig zitiert: 7
Erscheinungsjahre: 1999–2026

Liraglutid im Kontext von Peptide

Dieses Thema ist Teil unserer Welt „Peptide". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Peptide

Top-Studien zu Liraglutid

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

Liraglutide in mild to moderate Alzheimer’s disease: a phase 2b clinical trial
Nature Medicine2025n=204120 einflussreiche Zitationen
Liraglutide, a glucagon-like peptide 1 (GLP-1) agonist and antidiabetic drug, has shown neuroprotective effects in animal models. In this study, we aimed to evaluate the safety and efficacy of liraglutide in mild to moderate Alzheimer's…
Liraglutide prevents cognitive decline in a rat model of streptozotocin-induced diabetes independently from its peripheral metabolic effects.
Behavioural brain research201737 einflussreiche Zitationen
Diabetes has been identified as a risk factor for cognitive dysfunctions. Glucagone like peptide 1 (GLP-1) receptor agonists have neuroprotective effects in preclinical animal models. We evaluated the effects of GLP-1 receptor agonist,…
Systemic and gut microbiome changes with metformin and liraglutide in youth-onset type 2 diabetes: the MIGHTY study
Gut Microbes202524 einflussreiche Zitationen
Metformin (Met) and liraglutide (Lira) are preferred diabetes therapies that may improve glycemia by modulating the gut microbiome, but the mechanisms and pathways are unknown and few data exist in youth-onset type 2 diabetes (Y-T2D). In a…
Liraglutide alleviates ferroptosis in renal ischemia reperfusion injury via inhibiting macrophage extracellular trap formation
International Immunopharmacology202423 einflussreiche Zitationen
<h4>Background and purpose</h4>Renal transplantation and other conditions with transiently reduced blood flow is major cause of renal ischemia/reperfusion injury (RIRI), a therapeutic challenge clinically. This study investigated the role…
Liraglutide suppresses ferroptosis by upregulation NRF2 in type 2 diabetic cardiomyopathy
Peptides202520 einflussreiche Zitationen
Recent research indicates that inhibiting myocardial ferroptosis may help alleviate diabetic cardiomyopathy (DCM). Liraglutide (LIRA), a glucagon-like peptide-1 receptor agonist, has been shown to offer cardiovascular protective effects.…
Molecular Connectomics Reveals a Glucagon-Like Peptide 1 Sensitive Neural Circuit for Satiety
bioRxiv202312 einflussreiche Zitationen
Liraglutide and other agonists of the glucagon-like peptide 1 receptor (GLP-1RAs) are effective weight loss drugs, but how they suppress appetite remains unclear. One potential mechanism is by activating neurons which inhibit…
Liraglutide attenuates clozapine-induced mitochondrial dysfunction and improves energy metabolism in the brain of rats
Biochemical Pharmacology2025n=73 einflussreiche Zitationen
Chronic use of antipsychotics for schizophrenia (SCZ) often causes metabolic disturbances that exacerbate cognitive impairment, and the underlying mechanisms remain unclear. As a classic antipsychotic, the metabolic toxicity of clozapine…
Unveiling the potential therapeutic role of nifuroxazide and liraglutide combination in mitigating LPS-induced acute lung injury through modulation of AT1R/JAK-2/STAT-3 by ACE2/ Ang1‐7/MasR signaling in male albino rats: in vivo and in silico study
International Immunopharmacology20253 einflussreiche Zitationen
The current study investigated the possible therapeutic role of a combination of liraglutide and nifuroxazide in ameliorating the JAK2/STAT3/NFĸB signaling pathway by augmenting the counter-regulatory ACE2/Ang1-7/MAS receptor axis of the…
A Pharmacological Dose of Liraglutide Improves Mitochondrial Performance in Mouse Leydig Cells
International Journal of Molecular Sciences20253 einflussreiche Zitationen
Male fertility has declined over the years, partly due to metabolic disorders such as obesity and Type 2 diabetes. Antidiabetic drugs, including GLP-1 receptor agonists like liraglutide, are widely used to manage these conditions and aid…
The novel GLP-1 / GIP dual agonist DA3-CH is more effective than liraglutide in the MPTP mouse model of Parkinson's disease
European Journal of Pharmacology20253 einflussreiche Zitationen
Parkinson's disease is the second most common neurodegenerative disease worldwide with a high incidence rate. The abnormality of the Wnt/β-catenin signaling pathway is closely related to the occurrence of Parkinson's disease (PD).…

Weitere Themen in Peptide

Peptide-Überblick

Peptide, BPC-157, TB-500, Sicherheit und Studienlage.

Verabreichung

Subkutan, intramuskulär, nasal, oral, topisch — Bioverfügbarkeit und Sicherheit.

Autoimmunitäts-Risiko

Immun-Modulation kann sowohl Toleranz fördern als auch entgleisen lassen.

BPC-157

Peptid für Geweberegeneration, Heilung und sportliche Erholung.

Cerebrolysin

Schweinehirn-Peptid-Mix, Schlaganfall-Studien, in DE unzugelassen.

CJC-1295

GHRH-Analog, Halbwertszeit-Varianten und Pulse-Patterns.

Dihexa

Angiotensin-Derivat, kognitive/Neuroplastizitäts-Hinweise im Tiermodell.

GHK-Cu

Kupfer-Peptid für Hautgesundheit, Anti-Aging und Wundheilung.

GHRP-2

GH-Releaser, älter, Appetit-Stimulation als Nebeneffekt.

GHRP-6

GH-Releaser mit starker Appetit-Komponente.

Rebound nach GLP-1

Gewichtszunahme nach Absetzen ohne Lifestyle-Anker.

GLP-1 Nebenwirkungen

Übelkeit, Magenentleerung, Muskelverlust, Pankreatitis-Risiko.

Hexarelin

GH-Releaser, Toleranz-Aufbau schnell, kardiale Hinweise.

IGF-1 LR3

Modifiziertes IGF-1 mit langer Halbwertszeit — Hypertrophie, Krebsrisiko-Debatte.

Immune Modulation

Automatisch via Trend Scout entdeckt. Supplements targeting inflammation and immune resilience remain a central research area.. PubMed: 11956 Ergebnisse.

Injektionssicherheit

Sterile Technik, BAC-Wasser, Hautdesinfektion — medizinisches Thema.

Ipamorelin

Selektiver GH-Releaser, Cortisol-Sparing und Stack-Kombinationen.

KPV

Alpha-MSH-Fragment — entzündungshemmend, Darm, Haut, frühe Forschung.

LL-37

Antimikrobielles Peptid, Wundheilung, Immun-Modulation, frühe Forschung.

MK-677

Ghrelin-Mimetikum, kein Peptid streng genommen — Schlaf, Appetit, Glukose-Risiko.