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Immune ModulationStudienlage & Dosis

Automatisch via Trend Scout entdeckt. Supplements targeting inflammation and immune resilience remain a central research area.. PubMed: 11956 Ergebnisse.

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Studienlage in Zahlen

Studien gesamt
429
Mit Abstract
48
Meta / Systematic / RCT
181
Häufig zitiert
8
Erscheinungsjahre
2017–2026

Immune Modulation im Kontext von Peptide

Dieses Thema ist Teil unserer Welt „Peptide". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

Zur Welt Peptide

Top-Studien zu Immune Modulation

Sortiert nach einflussreichen Zitationen (Semantic Scholar) und Erscheinungsjahr.

  1. Efficacy and safety of allogeneic CD19 CAR NK-cell therapy in systemic lupus erythematosus: a case series in China.

    Lancet2026n=18Clinical Trial110 einflussreiche Zitationen

    <h4>Background</h4>Lately, autologous CD19-targeting chimeric antigen receptor (CAR) T cells have shown excellent efficacy in treatment of autoimmune diseases, but with great safety concerns, such as infections. In this study, we aimed to…

  2. Bioactive compounds in fermented foods: a systematic narrative review.

    Front Nutr2025n=50Systematic Review53 einflussreiche Zitationen

    This systematic narrative review aims to catalogue bioactive compounds that are formed during the fermentation process and identified as contributors to positive health outcomes in human clinical studies where fermented foods were used as…

  3. Immunomodulators and Advanced Therapies for Induction of Remission in Crohn's Disease: A Systematic Review and Network Meta-Analysis.

    Inflamm Bowel Dis2026n=20.724Meta-Analysis50 einflussreiche Zitationen

    <h4>Background</h4>Previous reviews for Crohn's disease (CD) treatment have rarely considered advanced and immunomodulator medical therapies together. Our aim was to compare all therapies for efficacy and safety in induction of…

    Befund: Upadacitinib and risankizumab were probably more effective than placebo for inducing endoscopic remission.

  4. Berberine in rheumatoid arthritis: a comprehensive review and meta-analysis of its anti-inflammatory and immunomodulatory mechanisms in animal models.

    Inflammopharmacology2025n=175Meta-Analysis42 einflussreiche Zitationen

    Berberine (BBR), an alkaloid derivative mostly found in Oregon grapes and barberry shoots, has several medical properties, including anti-microbial, anti-tumorigenic, and anti-inflammatory properties. As such, it is a superior alternative…

  5. Impact of Dietary Supplements on Clinical Outcomes and Quality of Life in Patients with Breast Cancer: A Systematic Review.

    Nutrients2025n=45systematic32 einflussreiche Zitationen

    Background: This systematic review aimed to evaluate the efficacy and safety of dietary supplements in breast cancer patients, focusing on their impact on clinical outcomes, treatment-related side effects, and therapy adherence. Methods:…

  6. Resveratrol in oral cancer: a systematic review of preclinical studies on its anticancer mechanisms and therapeutic potential.

    Med Oncol2025n=19Systematic Review27 einflussreiche Zitationen

    <h4>Objective</h4>Oral cancer remains a major global health challenge due to its aggressive nature, high recurrence rates, and limited treatment options. Resveratrol (RV), a naturally occurring polyphenol, has demonstrated promising…

  7. Current evidence and future direction on evaluating the anticancer effects of curcumin, gingerols, and shogaols in cervical cancer: A systematic review.

    PLoS One2024n=27Systematic Review19 einflussreiche Zitationen

    Cervical cancer ranked fourth most common malignancy among women worldwide despite the establishment of vaccination programmes. This systematic review evaluates the anti-cancer properties of turmeric and ginger bioactive compounds,…

  8. A comprehensive review of Glycyrrhiza glabra in the management of rheumatoid arthritis: ethnopharmacology, pharmacological mechanisms and synergistic therapeutic strategies.

    J Ethnopharmacol2026Systematic Review3 einflussreiche Zitationen

    <h4>Ethnopharmacological relevance</h4>Glycyrrhiza glabra L. (Fabaceae), commonly known as liquorice, has been valued for millennia in Ayurveda, Traditional Chinese Medicine (TCM), Persian medicine, and European folk practice. Across these…

  9. Phytotherapy as an adjunct to the treatment of rheumatoid arthritis - a systematic review of clinical trials.

    Phytomedicine2025n=14Systematic Review3 einflussreiche Zitationen

    <h4>Background</h4>Rheumatoid arthritis (RA) is a chronic systemic inflammatory autoimmune disease whose incidence is on an upward trend. The condition leads to progressive joint destruction, manifested by symptoms such as morning…

  10. Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review.

    RMD Open2025n=14Meta-Analysis3 einflussreiche Zitationen

    <h4>Objective</h4>To identify the best evidence on the efficacy of treatment interventions for inclusion body myositis (IBM) and to describe their safety.<h4>Methods</h4>Systematic review of randomised controlled trials (RCTs) of…

Häufige Fragen

Welche Dosierung wurde in den Studien untersucht?
• Allogeneic CD19 CAR NK-cell therapy (Schedule escalation from 7 days; dose escalation commencing at 0.75 × 10^9 CAR NK cells on day 0; three infusions per treatment cycle with lymphodepleting fludarabine and cyclophosphamide) • Fermented foods containing bioactive compounds formed during fermentation • Immunomodulators and advanced therapies, including anti-TNFs, anti-integrins, IL-12/23p40 antagonists, IL-23p19 antagonists, JAK inhibitors, and combination therapies with azathioprine/6-mercaptopurine (Various dose regimens; doses were combined in analysis)
Für welche Population gilt die Evidenz?
Die meisten Studien untersuchten: unknown.
Gibt es Sicherheitshinweise zu Immune Modulation?
• Grade 1 cytokine release syndrome occurred in 1 of 18 patients. • No neurotoxicity was observed. • No dose-limiting toxicities were reported. • Patients received lymphodepleting fludarabine and cyclophosphamide before CAR NK-cell infusions.

Weitere Themen in Peptide

Verabreichung

Subkutan, intramuskulär, nasal, oral, topisch — Bioverfügbarkeit und Sicherheit.

Autoimmunitäts-Risiko

Immun-Modulation kann sowohl Toleranz fördern als auch entgleisen lassen.

BPC-157

Peptid für Geweberegeneration, Heilung und sportliche Erholung.

Cerebrolysin

Schweinehirn-Peptid-Mix, Schlaganfall-Studien, in DE unzugelassen.

CJC-1295

GHRH-Analog, Halbwertszeit-Varianten und Pulse-Patterns.

Dihexa

Angiotensin-Derivat, kognitive/Neuroplastizitäts-Hinweise im Tiermodell.

GHK-Cu

Kupfer-Peptid für Hautgesundheit, Anti-Aging und Wundheilung.

GHRP-2

GH-Releaser, älter, Appetit-Stimulation als Nebeneffekt.

GHRP-6

GH-Releaser mit starker Appetit-Komponente.

Rebound nach GLP-1

Gewichtszunahme nach Absetzen ohne Lifestyle-Anker.

GLP-1 Nebenwirkungen

Übelkeit, Magenentleerung, Muskelverlust, Pankreatitis-Risiko.

Hexarelin

GH-Releaser, Toleranz-Aufbau schnell, kardiale Hinweise.

IGF-1 LR3

Modifiziertes IGF-1 mit langer Halbwertszeit — Hypertrophie, Krebsrisiko-Debatte.

Injektionssicherheit

Sterile Technik, BAC-Wasser, Hautdesinfektion — medizinisches Thema.

Ipamorelin

Selektiver GH-Releaser, Cortisol-Sparing und Stack-Kombinationen.

KPV

Alpha-MSH-Fragment — entzündungshemmend, Darm, Haut, frühe Forschung.

Liraglutid

Erste GLP-1-Generation für Diabetes/Adipositas — täglich, niedrigere Effektgröße.

LL-37

Antimikrobielles Peptid, Wundheilung, Immun-Modulation, frühe Forschung.

MK-677

Ghrelin-Mimetikum, kein Peptid streng genommen — Schlaf, Appetit, Glukose-Risiko.

Peptide-Grundlagen

Aminosäureketten <50 Reste, Signalpeptide, Hormone — Abgrenzung zu Proteinen.

Verwandte Themen aus anderen Welten

Methoden

Nutrigenomik & Ernährung

Personalisierte Ernährung über Genvariation: SNPs, Methylierung, MTHFR und wie genetische Profile Vitamin- und Diät-Strategien beeinflussen.

Methoden

Remote Work

Isolation, Boundaries, Bewegungsdefizit, Routinen.

Methoden

Strength Training

Hypertrophie, Sarkopenie-Prävention, Volumen vs. Intensität.

Methoden

Wasserqualität

Chlor, Schwermetalle, Mikroplastik, Filter-Optionen.

Longevity

Krebsfrüherkennung

Empfehlungen, Über-Diagnose, Galleri-Tests, Ganzkörper-MRT (kritisch).

Longevity

Exosomen

Zell-Kommunikation, regenerative Anwendungen, frühes Forschungsfeld.