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HypothalamusStudienlage & Dosis

Master-Regulator: Temperatur, Hunger, Schlaf, Hormonsteuerung.

Studienlage in Zahlen

Studien gesamt: 1.000
Mit Abstract: 48
Meta / Systematic / RCT: 0
Häufig zitiert: 30
Erscheinungsjahre: 1976–2026

Hypothalamus im Kontext von Hormone

Dieses Thema ist Teil unserer Welt „Hormone". Dort findest du Methodik, Studienlage und Hebel mit dem größten Effekt — sowie die Reihenfolge, in der sich Hebel sinnvoll aufeinander aufbauen.

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Top-Studien zu Hypothalamus

Sortiert nach einflussreichen Zitationen und Erscheinungsjahr.

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity.
Proceedings of the National Academy of Sciences of the United States of America1998200 einflussreiche Zitationen
We describe a hypothalamus-specific mRNA that encodes preprohypocretin, the putative precursor of a pair of peptides that share substantial amino acid identities with the gut hormone secretin. The hypocretin (Hcrt) protein products are…
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus.
Nature2004200 einflussreiche Zitationen
Obesity is an epidemic in Western society, and causes rapidly accelerating rates of type 2 diabetes and cardiovascular disease. The evolutionarily conserved serine/threonine kinase, AMP-activated protein kinase (AMPK), functions as a 'fuel…
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus.
Endocrinology2005200 einflussreiche Zitationen
Obesity has reached epidemic proportions in several regions of the world. General changes in lifestyle, including consumption of fat-rich food, are among the most important factors leading to an unprecedented increase in the prevalence of…
Identification of nesfatin-1 as a satiety molecule in the hypothalamus.
Nature2006200 einflussreiche Zitationen
The brain hypothalamus contains certain secreted molecules that are important in regulating feeding behaviour. Here we show that nesfatin, corresponding to NEFA/nucleobindin2 (NUCB2), a secreted protein of unknown function, is expressed in…
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.
Cell metabolism2007160 einflussreiche Zitationen
Adiponectin has been shown to stimulate fatty acid oxidation and enhance insulin sensitivity through the activation of AMP-activated protein kinase (AMPK) in the peripheral tissues. The effects of adiponectin in the central nervous system,…
HypoMap-a unified single-cell gene expression atlas of the murine hypothalamus.
Nature metabolism2022158 einflussreiche Zitationen
The hypothalamus plays a key role in coordinating fundamental body functions. Despite recent progress in single-cell technologies, a unified catalog and molecular characterization of the heterogeneous cell types and, specifically, neuronal…
Identification of targets of leptin action in rat hypothalamus.
Journal of Clinical Investigation199673 einflussreiche Zitationen
The hypothesis that leptin (OB protein) acts in the hypothalamus to reduce food intake and body weight is based primarily on evidence from leptin-deficient, ob/ob mice. To investigate whether leptin exerts similar effects in normal…
Sleep and the hypothalamus.
Science (New York, N.Y.)202372 einflussreiche Zitationen
Neural substrates of wakefulness, rapid eye movement sleep (REMS), and non-REMS (NREMS) in the mammalian hypothalamus overlap both anatomically and functionally with cellular networks that support physiological and behavioral homeostasis.…
Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat
The Journal of comparative neurology198247 einflussreiche Zitationen
A method that allows the concurrent localization of an antigen and a retrogradely transported fluorescent dye (true blue) was used to identify, immunohistochemically, cells in the paraventricular nucleus of the hypothalamus (PVH) that…
Functional identification of an aggression locus in the mouse hypothalamus
Nature201046 einflussreiche Zitationen
Electrical stimulation of certain hypothalamic regions in cats and rodents can elicit attack behaviour, but the exact location of relevant cells within these regions, their requirement for naturally occurring aggression and their…