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Vitamin C (Recovery)Evidence & Dosage

Collagen synthesis, tendon repair — the timing debate around hypertrophy.

Evidence at a glance

Total studies
343
With abstract
50
Meta / Systematic / RCT
96
Highly cited
50
Publication years
1979–2026

Vitamin C (Recovery) in the context of Recovery

This topic is part of our "Recovery" world. There you'll find methodology, evidence and the highest-impact levers — plus the order in which they sensibly build on each other.

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Top studies on Vitamin C (Recovery)

Ranked by influential-citation count and publication year.

  1. MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20,536 high-risk individuals: a randomised placebo-controlled trial.

    Lancet (London, England)2002200 influential citations

    <h4>Background</h4>It has been suggested that increased intake of various antioxidant vitamins reduces the incidence rates of vascular disease, cancer, and other adverse outcomes.<h4>Methods</h4>20,536 UK adults (aged 40-80) with coronary…

  2. Use of antioxidant vitamins for the prevention of cardiovascular disease: meta-analysis of randomised trials.

    Lancet (London, England)2003n=81,788178 influential citations

    <h4>Introduction</h4>Oxidised LDL is thought to play an important part in the pathogenesis of atherosclerosis. Observational studies have associated alpha tocopherol (vitamin E), beta carotene, or both, with reductions in cardiovascular…

  3. The SU.VI.MAX Study: a randomized, placebo-controlled trial of the health effects of antioxidant vitamins and minerals.

    Archives of internal medicine2004n=7,876177 influential citations

    <h4>Background</h4>It has been suggested that a low dietary intake of antioxidant vitamins and minerals increases the incidence rate of cardiovascular disease and cancer. To date, however, the published results of randomized,…

  4. Systematic review of herbs and dietary supplements for glycemic control in diabetes.

    Diabetes care2003n=4,565125 influential citations

    <h4>Objective</h4>To conduct a systematic review of the published literature on the efficacy and safety of herbal therapies and vitamin/mineral supplements for glucose control in patients with diabetes.<h4>Research design and…

  5. Nutritional interventions for preventing and treating pressure ulcers.

    Cochrane Database Syst Rev2024n=792Meta-Analysis115 influential citations

    <h4>Background</h4>Pressure ulcers are localized injuries to the skin or the underlying tissue, or both, and are common in older and immobile people, people with diabetes, vascular disease, or malnutrition, as well as those who require…

    Finding: Compared with a standard diet, energy, protein and micronutrient supplements may result in little to no difference in pressure ulcer incidence.

  6. Antioxidant supplements for prevention of gastrointestinal cancers: a systematic review and meta-analysis.

    Lancet (London, England)2004103 influential citations

    <h4>Background</h4>Oxidative stress can cause cancer. Our aim was to establish whether antioxidant supplements reduce the incidence of gastrointestinal cancer and mortality.<h4>Methods</h4>With the Cochrane Collaboration methodology, we…

  7. Vitamin and Mineral Supplements for the Primary Prevention of Cardiovascular Disease and Cancer: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.

    JAMA2022n=739Systematic Review101 influential citations

    <h4>Importance</h4>Cardiovascular disease and cancer are the 2 leading causes of death in the US, and vitamin and mineral supplementation has been proposed to help prevent these conditions.<h4>Objective</h4>To review the benefits and harms…

  8. Vitamins C and E and the risks of preeclampsia and perinatal complications.

    The New England journal of medicine2006n=1,87797 influential citations

    <h4>Background</h4>Supplementation with antioxidant vitamins has been proposed to reduce the risk of preeclampsia and perinatal complications, but the effects of this intervention are uncertain.<h4>Methods</h4>We conducted a multicenter,…

  9. A new recommended dietary allowance of vitamin C for healthy young women.

    Proceedings of the National Academy of Sciences of the United States of America200192 influential citations

    The recently released Recommended Dietary Allowance of vitamin C for women, 75 mg daily, was based on data for men. We now report results of a depletion-repletion study with healthy young women hospitalized for 186 +/- 28 days, using…

  10. Combination therapy of vitamin C and thiamine for septic shock: a multi-centre, double-blinded randomized, controlled study.

    Intensive Care Med2020n=111RCT86 influential citations

    <h4>Purpose</h4>To evaluate the effects of early combination therapy with intravenous vitamin C and thiamine on recovery from organ failure in patients with septic shock.<h4>Methods</h4>The ascorbic acid and thiamine effect in septic shock…

Frequently asked

Are there safety considerations for Vitamin C (Recovery)?
• Very few adverse effects were reported. • Gastrointestinal side effects were reported for protein supplements, but evidence was very uncertain. • Side effects of energy, protein and micronutrient supplements were very uncertain. • Side effects of collagen supplements were very uncertain.

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